{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,19]],"date-time":"2025-01-19T05:16:23Z","timestamp":1737263783667,"version":"3.33.0"},"reference-count":11,"publisher":"Baishideng Publishing Group Inc.","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Gastroenterol"],"abstract":"<jats:p>This letter comments on the recently published manuscript by Yu et al , in which the authors revealed a novel mechanism by which the m6A-modified long noncoding RNA kinesin family member 9-antisense RNA 1 promotes stemness and sorafenib resistance of hepatocellular carcinoma (HCC) through ubiquitin-specific peptidase 1-mediated deubiquitination of oncogene short stature homeobox 2. Given the high mortality rate and poor prognosis of HCC, the findings by Yu et al  open a new avenue for overcoming HCC burden by focusing on kinesin family member 9-antisense RNA 1 and short stature homeobox 2 as prognostic markers and therapeutic targets.<\/jats:p>","DOI":"10.3748\/wjg.v31.i7.103400","type":"journal-article","created":{"date-parts":[[2025,1,18]],"date-time":"2025-01-18T06:55:36Z","timestamp":1737183336000},"source":"Crossref","is-referenced-by-count":0,"title":["Mechanistic link between long noncoding RNA and stability of oncogene reveals stemness and chemoresistance of hepatocellular carcinoma"],"prefix":"10.3748","volume":"31","author":[{"given":"Yu-Bo","family":"Liang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xing-Ming","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wan-Ling","family":"Luo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Ke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","published-online":{"date-parts":[[2025,2,21]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jncc.2023.02.001"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.2147\/JHC.S462168"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.32604\/biocell.2024.050396"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2023.1204513"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.20892\/j.issn.2095-3941.2022.0449"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.cytogfr.2024.08.007"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.32604\/biocell.2021.017289"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v30.i48.5174"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.2174\/0118761429273223231124072223"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.2174\/0118761429310703240823045808"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.2174\/0109298673298862240510073543"}],"container-title":["World Journal of Gastroenterology"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/1007-9327\/full\/v31\/i7\/103400.htm","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wjgnet.com\/1007-9327\/full\/v31\/i7\/103400.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,18]],"date-time":"2025-01-18T06:56:12Z","timestamp":1737183372000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/1007-9327\/full\/v31\/i7\/103400.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,21]]},"references-count":11,"journal-issue":{"issue":"7"},"alternative-id":["103400"],"URL":"https:\/\/doi.org\/10.3748\/wjg.v31.i7.103400","relation":{},"ISSN":["1007-9327"],"issn-type":[{"value":"1007-9327","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2,21]]}}}