{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T00:40:11Z","timestamp":1789000811333,"version":"build-2803163510"},"reference-count":25,"publisher":"Baishideng Publishing Group Inc.","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Gastroenterol"],"abstract":"BACKGROUND<\/jats:p>\n Accurate T-staging of early gastric cancer (EGC) is critical for selecting the most appropriate treatment strategy. Although the reported diagnostic performance of endoscopic ultrasound (EUS) in determining T stage varies among studies, it continues to serve as an important tool in the pretreatment assessment of EGC.<\/jats:p>\n AIM<\/jats:p>\n To identify clinicopathological factors that affect the diagnostic accuracy of EUS in EGC, with particular emphasis on mucosal lesions (Tis\/T1a).<\/jats:p>\n METHODS<\/jats:p>\n We included EGC patients who underwent endoscopic resection or gastrectomy. The diagnostic accuracy of EUS was assessed by comparing its T-stage evaluation with the histopathological results of the resected specimens. Additionally, potential risk factors associated with the over staging of Tis\/T1a lesions by EUS were investigated.<\/jats:p>\n RESULTS<\/jats:p>\n A total of 209 patients were included in this study. The overall diagnostic accuracy of EUS for T staging was 74.64%. However, the sensitivity of EUS in identifying Tis\/T1a gastric cancers was relatively low at 41.25%. Risk factor analysis showed that younger age (P = 0.035) and the presence of ulceration (P < 0.001) were significantly associated with over staging of Tis\/T1a lesions. In multivariate analysis, ulceration remained the only independent predictor of over staging, with an odds ratio of 15.25 (95% confidence interval: 3.23-71.98; P < 0.001).<\/jats:p>\n CONCLUSION<\/jats:p>\n The accuracy of EUS for staging Tis\/T1a early gastric cancer is markedly reduced when gastric ulceration is present. Therefore, EUS-based staging should be interpreted cautiously in patients with ulcer-related lesions.<\/jats:p>","DOI":"10.3748\/wjg.v32.i7.116463","type":"journal-article","created":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T09:24:39Z","timestamp":1770283479000},"source":"Crossref","is-referenced-by-count":1,"title":["Endoscopic ultrasound in early gastric cancer: Diagnostic accuracy and Tis\/T1a lesion over staging risks"],"prefix":"10.3748","volume":"32","author":[{"given":"Xue-Yan","family":"Qiao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ze-Hua","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi-Yong","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ge","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2060","published-online":{"date-parts":[[2026,2,21]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000005332"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v29.i16.2452"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.5009\/gnl14401"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.4251\/wjgo.v16.i4.1154"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.761295"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1186\/s12957-017-1176-6"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2023.1124498"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1255617"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.4253\/wjge.v8.i16.558"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000003955"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.5009\/gnl19243"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1186\/s12876-021-01945-9"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1007\/s10120-020-01100-5"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(89)91568-0"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD009944.pub2"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2008.01923.x"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2015.01.022"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-010-1279-4"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2006.09.5224"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2007.06.012"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-010-1112-0"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.18926\/AMO\/45269"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.5946\/ce.2015.48.4.297"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1093\/gastro\/got010"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0164339"}],"container-title":["World Journal of Gastroenterology"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/1007-9327\/full\/v32\/i7\/116463.htm","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wjgnet.com\/1007-9327\/full\/v32\/i7\/116463.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T09:25:02Z","timestamp":1770283502000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/1007-9327\/full\/v32\/i7\/116463.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,21]]},"references-count":25,"journal-issue":{"issue":"7"},"alternative-id":["116463"],"URL":"https:\/\/doi.org\/10.3748\/wjg.v32.i7.116463","relation":{},"ISSN":["1007-9327"],"issn-type":[{"value":"1007-9327","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2,21]]}}}