{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T15:58:38Z","timestamp":1793289518402,"version":"4.5.0"},"reference-count":38,"publisher":"Baishideng Publishing Group Inc.","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["WJG"],"published-print":{"date-parts":[[2002]]},"DOI":"10.3748\/wjg.v8.i5.883","type":"journal-article","created":{"date-parts":[[2015,11,22]],"date-time":"2015-11-22T21:09:49Z","timestamp":1448226589000},"page":"883","source":"Crossref","is-referenced-by-count":108,"title":["Estrogen reduces CCL4- induced liver fibrosis in rats"],"prefix":"10.3748","volume":"8","author":[{"given":"Jun-Wang","family":"Xu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2060","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6363(99)00159-5"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(01)00055-1"},{"key":"ref3","unstructured":"Yan JC, MA JY, Pan BR, MA LS. Study of hepatitis B in China. Shijie Huaren Xiaohua Zazhi 2001;9:611-616."},{"key":"ref4","doi-asserted-by":"crossref","unstructured":"Ji XL. Fine-needle aspiration cytology of liver diseases. World J Gastroenterol 1999;5:95-97.","DOI":"10.3748\/wjg.v5.i2.95"},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"Nie QH, Cheng YQ, Xie YM, Zhou YX, Cao YZ. Inhibiting effect of antisense oligonucleotides phosphorthioate on gene expression of TIMP-1 in rat liver fibrosis. World J Gastroenterol 2001;7:363-369.","DOI":"10.3748\/wjg.v7.i3.363"},{"key":"ref6","doi-asserted-by":"crossref","unstructured":"Dai WJ, Jiang HC. Advances in gene therapy of liver cirrhosis: a review. World J Gastroenterol 2001;7:1-8.","DOI":"10.3748\/wjg.v7.i1.1"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(01)00050-2"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"Du WD, Zhang YE, Zhai WR, Zhou XM. Dynamic changes of type I, III and IV collagen synthesis and distribution of collagen-producing cells in carbon tetrachloride-induced rat liver fibrosis. World J Gastroenterol 1999;5:397-403.","DOI":"10.3748\/wjg.v5.i5.397"},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"Wu CH. Fibrodynamics-elucidation of the mechanisms and sites of liver fibrogenesis. World J Gastroenterol 1999;5:388-390.","DOI":"10.3748\/wjg.v5.i5.388"},{"key":"ref10","doi-asserted-by":"crossref","unstructured":"Liu HL, Li XH, Wang DY, Yang SP. Matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 expression in fibrotic rat liver. World J Gastroenterol 2000;6:881-884.","DOI":"10.3748\/wjg.v6.i6.881"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-483X(00)00352-8"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(98)80318-8"},{"key":"ref13","doi-asserted-by":"crossref","unstructured":"Gao ZL, Li DG, Lu HM, Gu XH. The effect of retinoic acid on Ito cell proliferation and content of DNA and RNA. World J Gastroenterol 1999;5:443-444.","DOI":"10.3748\/wjg.v5.i5.443"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(01)00163-5"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(01)02655-2"},{"key":"ref16","doi-asserted-by":"crossref","unstructured":"Wei HS, Li DG, Lu HM, Zhan YT, Wang ZR, Huang X, Zhang J, Cheng JL, Xu QF. Effects of AT1 receptor antagonist, losartan, on rat hepatic fibrosis induced by CCl (4). World J Gastroenterol 2000;6:540-545.","DOI":"10.3748\/wjg.v6.i6.824"},{"key":"ref17","doi-asserted-by":"crossref","unstructured":"Huang X, Li DG, Wang ZR, Wei HS, Cheng JL, Zhan YT, Zhou X, Xu QF, Li X, Lu HM. Expression changes of activin A in the development of hepatic fibrosis. World J Gastroenterol 2001;7:37-41.","DOI":"10.3748\/wjg.v7.i1.37"},{"key":"ref18","doi-asserted-by":"crossref","unstructured":"Li X, Meng Y, Yang XS, Wu PS, Li SM, Lai WY. CYP11B2 expression in HSCs and its effect on hepatic fibrogenesis. World J Gastroenterol 2000;6:885-887.","DOI":"10.3748\/wjg.v6.i6.885"},{"key":"ref19","doi-asserted-by":"crossref","unstructured":"Huang GC, Zhang JS, Zhang YE. Effects of retinoic acid on proliferation, phenotype and expression of cyclin-dependent kinase inhibitors in TGF-beta1-stimulated rat hepatic stellate cells. World J Gastroenterol 2000;6:819-823.","DOI":"10.3748\/wjg.v6.i6.819"},{"key":"ref20","doi-asserted-by":"crossref","unstructured":"Wei HS, Lu HM, Li DG, Zhan YT, Wang ZR, Huang X, Cheng JL, Xu QF. The regulatory role of AT 1 receptor on activated HSCs in hepatic fibrogenesis: effects of RAS inhibitors on hepatic fibrosis induced by CCl (4). World J Gastroenterol 2000;6:824-828.","DOI":"10.3748\/wjg.v6.i6.824"},{"key":"ref21","doi-asserted-by":"crossref","unstructured":"Chen PS, Zhai WR, Zhou XM, Zhang JS, Zhang YE, Ling YQ, Gu YH. Effects of hypoxia, hyperoxia on the regulation of expression and activity of matrix metalloproteinase-2 in hepatic stellate cells. World J Gastroenterol 2001;7:647-651.","DOI":"10.3748\/wjg.v7.i5.647"},{"key":"ref22","doi-asserted-by":"crossref","unstructured":"Wang JY, Zhang QS, Guo JS, Hu MY. Effects of glycyrrhetinic acid on collagen metabolism of hepatic stellate cells at different stages of liver fibrosis in rats. World J Gastroenterol 2001;7:115-119.","DOI":"10.3748\/wjg.v7.i1.115"},{"key":"ref23","unstructured":"Xie YM, Nie QH, Chou YX, Cheng YQ, Kang WZ. Detection of TIMP-1 and TIMP-2 RNA expressions in cirrhotic liver tissue using digoxigenin labelled probe by <italic>in situ<\/italic> hybridization. Shijie Huaren Xiaohua Zazhi 2001;9:251-254."},{"key":"ref24","unstructured":"Lu X, Liu CH, Xu GF, Chen WH, Liu P. Successive observation of laminin and collagen IV on hepatic sinusoid during the formation of the liver fibrosis in rats. Shijie Huaren Xiaohua Zazhi 2001;9:260-262."},{"key":"ref25","unstructured":"Yao XX, Tang YW, Yao DM, Xiu HM. Effect of Yigan Decoction on the expression of type I, III collagen proteins in experimental hepatic fibrosis in rats. Shijie Huaren Xiaohua Zazhi 2001;9:263-267."},{"key":"ref26","unstructured":"Huang GC, Zhang JS. Intercellular signal transduction of activated hepatic stellate cells. Shijie Huaren Xiaohua Zazhi 2001;9:1056-1060."},{"key":"ref27","unstructured":"Liu T, Hu JH, Cai Q, Ji YP. Signal conducting molecule in hepatic stellate cells. Shijie Huaren Xiaohua Zazhi 2001;9:805-807."},{"key":"ref28","doi-asserted-by":"crossref","unstructured":"Lei DX, Peng CH, Peng SY, Jiang XC, Wu YL, Shen HW. Safe upper limit of intermittent hepatic inflow occlusion for liver resection in cirrhotic rats. World J Gastroenterol 2001;7:713-717.","DOI":"10.3748\/wjg.v7.i5.713"},{"key":"ref29","unstructured":"Li D, Zhang LJ, Chen ZX, Huang YH, Whang XZ. Effects of TNF&alpha; IL-6 and IL-10 on the development of experimental rat liver fibrosis. Shijie Huaren Xiaohua Zazhi 2001;9:1242-1245."},{"key":"ref30","doi-asserted-by":"crossref","unstructured":"Wang LT, Zhang B, Chen JJ. Effect of anti-fibrosis compound on collagen expression of hepatic cells in experimental liver fibrosis of rats. World J Gastroenterol 2000;6:877-880.","DOI":"10.3748\/wjg.v6.i6.877"},{"key":"ref31","unstructured":"Zhang YT, Chang XM, Li X, LiHL . Effects of spironolactone on expression of type I\/III collagen proteins in rat hepatic fibrosis. Shijie Huaren Xiaohua Zazhi 2001;9:1120-1124."},{"key":"ref32","unstructured":"Yang Q, Yan YC, Gao YX. Inhibitory effect of Quxianruangan capsulae on liver fibrosis in rats and chronic hepatitis atients. Shijie Huaren Xiaohua Zazhi 2001;9:1246-1249."},{"key":"ref33","doi-asserted-by":"crossref","unstructured":"Yao XX, Tang YW, Yao DM, Xiu HM. Effects of Yigan Decoction on proliferation and apoptosis of hepatic stellate cells. World J Gastroenterol 2002;8:511-514.","DOI":"10.3748\/wjg.v8.i3.511"},{"key":"ref34","doi-asserted-by":"crossref","unstructured":"Parola M, Robino G. Oxidative stress-related molecules and liver fibrosis. J Hepatol 2001;35:297-306.","DOI":"10.1016\/S0168-8278(01)00142-8"},{"key":"ref35","unstructured":"Chen WH, Liu P, Xu GF, Lu X, Xiong WG, Li FH, Liu CH. Role of lipid peroxidation in liver fibrogenesis induced by dimethylnitrosamine in rats. Shijie Huaren Xiaohua Zazhi 2001;9:645-648."},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(99)80102-0"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-2999(00)00683-X"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(99)80103-2"}],"container-title":["World Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.wjgnet.com\/1007-9327\/full\/v8\/i5\/883.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T16:00:12Z","timestamp":1567353612000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.wjgnet.com\/1007-9327\/full\/v8\/i5\/883.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002]]},"references-count":38,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2002]]}},"URL":"https:\/\/doi.org\/10.3748\/wjg.v8.i5.883","relation":{},"ISSN":["1007-9327"],"issn-type":[{"value":"1007-9327","type":"print"}],"subject":[],"published":{"date-parts":[[2002]]}}}