{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T08:43:34Z","timestamp":1771231414462,"version":"3.50.1"},"reference-count":43,"publisher":"Beilstein Institut","license":[{"start":{"date-parts":[[2017,1,26]],"date-time":"2017-01-26T00:00:00Z","timestamp":1485388800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2017,1,26]],"date-time":"2017-01-26T00:00:00Z","timestamp":1485388800000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2017,1,26]],"date-time":"2017-01-26T00:00:00Z","timestamp":1485388800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Beilstein J. Org. Chem."],"accepted":{"date-parts":[[2017,1,10]]},"abstract":"<jats:p>In this paper, we introduce a novel and convenient method for the transformation of heterocyclic amides into heteocyclic thioamides. A two-step approach was applied for this transformation: Firstly, we applied a chlorination of the heterocyclic amides to afford the corresponding chloroheterocycles. Secondly, the chloroherocycles and <jats:italic>N<\/jats:italic>-cyclohexyl dithiocarbamate cyclohexylammonium salt were heated in chloroform for 12 h at 61 \u00b0C to afford heteocyclic thioamides in excellent yields.<\/jats:p>","DOI":"10.3762\/bjoc.13.20","type":"journal-article","created":{"date-parts":[[2017,1,26]],"date-time":"2017-01-26T10:15:49Z","timestamp":1485425749000},"page":"174-181","source":"Crossref","is-referenced-by-count":15,"title":["A novel method for heterocyclic amide\u2013thioamide transformations"],"prefix":"10.3762","volume":"13","author":[{"given":"Walid","family":"Fathalla","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ibrahim A I","family":"Ali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pavel","family":"Pazdera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2086","published-online":{"date-parts":[[2017,1,26]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1021\/cr040650b"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1021\/cr900243d"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1021\/jo0256742"},{"key":"ref4","first-page":"1793","author":"Libermann","year":"1959","journal-title":"Bulletin de la Soci\u00e9t\u00e9 Chimique de France"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1021\/jo01174a007"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1021\/jo01110a026"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1248\/yakushi1947.78.7_729","volume":"78","author":"Asano","year":"1958","journal-title":"Yakugaku Zasshi\/Journal of the Pharmaceutical Society of Japan"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/ardp.200600012"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3390\/51201210"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.3390\/60600557"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1002\/jhet.5570390605"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1080\/17415990701759685"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"245","DOI":"10.3998\/ark.5550190.0009.c26","volume":"xii","author":"Fathalla","year":"2008","journal-title":"ARKIVOC"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1002\/hc.20203"},{"key":"ref16","first-page":"179","volume":"xiii","author":"Fathalla","year":"2008","journal-title":"ARKIVOC"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1007\/s10593-015-1661-1"},{"key":"ref18","series-title":"Science of Synthesis: Houben-Weyl","first-page":"726","volume-title":"Methods of molecular hetarenes and related ring systems","volume":"16","author":"Yamamoto","year":"2003"},{"key":"ref19","first-page":"905","volume":"38","author":"Sundaram","year":"1999","journal-title":"Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1515\/HC.2004.10.4-5.325"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1246\/cl.1979.131"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1007\/s10847-014-0432-4"},{"key":"ref23","first-page":"779","volume":"33","author":"Derbala","year":"1994","journal-title":"Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry"},{"key":"ref24","first-page":"251","volume":"128","author":"Ismail","year":"1991","journal-title":"Acta Chimica Hungarica"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1007\/s10593-010-0435-z"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2011.03.015"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.cclet.2010.11.002"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1055\/s-0031-1296214"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2014.07.008"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2011.01.055"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1002\/jccs.200700061"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1021\/jm9705418"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.3184\/030823410X12658886079090"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2010.11.022"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2008.02.097"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1080\/00397911.2012.674168"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2008.06.006"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1007\/BF00470545"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1246\/nikkashi1948.92.1005"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.3762\/bjoc.8.6"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1080\/00397919708003379"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2013.01.067"},{"key":"ref45","first-page":"620","author":"Legrand","year":"1961","journal-title":"Bulletin de la Soci\u00e9t\u00e9 Chimique de France"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.3390\/60400323"}],"container-title":["Beilstein Journal of Organic Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.beilstein-journals.org\/bjoc\/articles\/13\/20","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.beilstein-journals.org\/bjoc\/content\/pdf\/1860-5397-13-20.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.beilstein-journals.org\/bjoc\/content\/13\/1\/20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/www.beilstein-journals.org\/bjoc\/articles\/13\/20","content-type":"text\/html","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,23]],"date-time":"2021-06-23T17:10:25Z","timestamp":1624468225000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.beilstein-journals.org\/bjoc\/articles\/13\/20"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,26]]},"references-count":43,"URL":"https:\/\/doi.org\/10.3762\/bjoc.13.20","archive":["Portico"],"relation":{},"ISSN":["1860-5397"],"issn-type":[{"value":"1860-5397","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1,26]]}}}