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Chem."],"accepted":{"date-parts":[[2021,11,24]]},"abstract":"<jats:p>HPLC\/DAD-based chemical investigation of a coral-associated gliding bacterium of the genus <jats:italic>Tenacibaculum<\/jats:italic> yielded three desferrioxamine-class siderophores, designated tenacibactins K (<jats:bold>1<\/jats:bold>), L (<jats:bold>2<\/jats:bold>), and M (<jats:bold>3<\/jats:bold>). Their chemical structures, comprising repeated cadaverine\u2013succinic acid motifs terminated by a hydroxamic acid functionality, were elucidated by NMR and negative MS\/MS experiments. Compounds <jats:bold>1<\/jats:bold>\u2013<jats:bold>3<\/jats:bold> were inactive against bacteria and a yeast but displayed cytotoxicity against 3Y1 rat embryonic fibroblasts and P388 murine leukemia cells at GI<jats:sub>50<\/jats:sub> in submicromolar to micromolar ranges. 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