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Chem."],"accepted":{"date-parts":[[2023,5,22]]},"abstract":"<jats:p>\n                    Quinoline-based sulfonyl derivatives, and especially sulfonamides, are relevant and promising structures for drug design. We have developed a new convenient protocol for the synthesis of 3-sulfonyl-substituted quinolines (sulfonamides and sulfones). The approach is based on a Knoevenagel condensation\/aza-Wittig reaction cascade involving\n                    <jats:italic>o<\/jats:italic>\n                    -azidobenzaldehydes and ketosulfonamides or ketosulfones as key building blocks. The protocol is appropriate for both ketosulfonyl reagents and \u03b1-sulfonyl-substituted alkyl acetates providing the target quinoline derivatives in good to excellent yields.\n                  <\/jats:p>","DOI":"10.3762\/bjoc.19.60","type":"journal-article","created":{"date-parts":[[2023,6,9]],"date-time":"2023-06-09T03:16:18Z","timestamp":1686280578000},"page":"800-807","source":"Crossref","is-referenced-by-count":5,"title":["Facile access to 3-sulfonylquinolines via Knoevenagel condensation\/aza-Wittig reaction cascade involving\n                    <i>ortho<\/i>\n                    -azidobenzaldehydes and \u03b2-ketosulfonamides and 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