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Chem."],"accepted":{"date-parts":[[2025,6,18]]},"abstract":"<jats:p>\n                    The C2-amination of benzoxazole offers wide-ranging potential for substrate expansion and the functionalisation of bioactive compounds. This study presents a green and efficient C\u2013H amination, catalysed by CuCl and CuCl\n                    <jats:sub>2<\/jats:sub>\n                    , in acetonitrile without acidic, basic or oxidant additives that is accelerated by microwave (MW) irradiation and is completed in 1.5\u20132 h. A solid Cu(I) catalyst supported on aminated silica made the process cost-effective and heterogeneous, thus simplifying work-up and minimising free copper in solution. The catalyst was found to be regeneratable and reusable for up to eight cycles. The optimised method facilitated the synthesis of various benzoxazole derivatives, demonstrating its versatility and practical applicability.\n                  <\/jats:p>","DOI":"10.3762\/bjoc.21.108","type":"journal-article","created":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T11:34:18Z","timestamp":1752579258000},"page":"1462-1476","source":"Crossref","is-referenced-by-count":4,"title":["Microwave-enhanced additive-free C\u2013H amination of benzoxazoles catalysed by supported 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