{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T21:26:01Z","timestamp":1748294761392,"version":"3.37.0"},"reference-count":0,"publisher":"American Academy of Audiology","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["j am acad audiol"],"published-print":{"date-parts":[[2005,2,1]]},"abstract":"<jats:p>The present study investigates the effect of small amounts of outer hair cell (OHC) loss on distortion product otoacoustic emission (DPOAE) levels and evoked potential permanent threshold shifts (PTS) in a population of 12 noise-exposed chinchillas. The group mean DPOAE level, which\n decreased by up to ~15 dB in the presence of less than 8 dB PTS and 15% OHC loss, indicates that DPOAEs can detect an underlying cochlear pathology (i.e., OHC damage\/loss) despite the presence of normal to near normal thresholds. The sensitivity of DPOAEs in detecting OHC loss makes this test\n measure suited for diagnosing sensorineural hearing impairment, particularly when abnormal auditory symptoms (i.e., speech discrimination problems) are associated with a normal audiogram in the clinical setting and as part of a hearing conservation program. El presente estudio investiga el\n efecto sobre los niveles de las emisiones otoac\u00fasticas por productos de distorsi\u00f3n (DPOAE) y sobre los cambios permanentes de umbral (PTS) de los potenciales evocados, de la p\u00e9rdida de peque\u00f1as cantidades de c\u00e9lulas ciliadas externas (OHC) en una poblaci\u00f3n\n de 12 chichillas expuestas a ruido. El nivel promedio grupal de las DPOAE, que disminuye hasta en ~15 dB en presencia de 8 dB de PTS y de un 15% de p\u00e9rdida de OHC, indica que las DPOAE pueden detectar una patolog\u00eda coclear subyacente (p.e., da\u00f1o\/p\u00e9rdida de OHC)\n a pesar de la presencia de umbrales auditivos normales o cercanos a la normalidad. La sensibilidad de las DPOAE para detectar la p\u00e9rdida de OHC convierte a esta medici\u00f3n en algo apropiado para diagnosticar p\u00e9rdidas auditivas sensorineurales, particularmente cuando los\n s\u00edntomas auditivos anormales (p.e., problemas de discriminaci\u00f3n del lenguaje) est\u00e1n asociados con un audiograma normal en el contexto cl\u00ednico y como parte de un programa de conservaci\u00f3n auditiva.<\/jats:p>","DOI":"10.3766\/jaaa.16.2.2","type":"journal-article","created":{"date-parts":[[2008,4,22]],"date-time":"2008-04-22T23:54:28Z","timestamp":1208908468000},"page":"69-78","source":"Crossref","is-referenced-by-count":16,"title":["Sensitivity of Distortion Product Otoacoustic Emissions in Noise-Exposed Chinchillas"],"prefix":"10.3766","volume":"16","author":[{"given":"Bob","family":"Davis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roger P.","family":"Hamernik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2087","container-title":["Journal of the American Academy of Audiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ingentaconnect.com\/content\/aaa\/jaaa\/2005\/00000016\/00000002\/art00002","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T23:12:04Z","timestamp":1738797124000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ingentaconnect.com\/content\/10.3766\/jaaa.16.2.2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,2,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2005,2,1]]}},"alternative-id":["1050-0545(20050201)16:2L.69;1-"],"URL":"https:\/\/doi.org\/10.3766\/jaaa.16.2.2","relation":{},"ISSN":["1050-0545"],"issn-type":[{"type":"print","value":"1050-0545"}],"subject":[],"published":{"date-parts":[[2005,2,1]]}}}