{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T23:35:37Z","timestamp":1772753737561,"version":"3.50.1"},"reference-count":0,"publisher":"American Academy of Audiology","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["j am acad audiol"],"published-print":{"date-parts":[[2006,1,1]]},"abstract":"<jats:p>M\u00e9ni\u00e8re's disease (MD) is a complex, multifactorial disorder of the inner ear that is the most common cause of the syndrome of episodic vertigo combined with fluctuating hearing loss. In spite of a century of investigation, the etiology and pathophysiology of MD remain\n controversial and incompletely understood. Among the factors that have contributed to these controversies are the absence of (1) a validated clinical test, (2) an appropriate animal model, and (3) a specific treatment. Nonetheless, physicians are able to assist MD patients with a variety of\n tailored, symptom-specific medications and therapies. Given that the vertigo induced by MD, in general, is self-limited, the long-term outlook for balance function is good. The same cannot be said for the hearing dysfunction of MD. La enfermedad de M\u00e9ni\u00e8re (MD) es un trastorno\n complejo y multifactorial del o\u00eddo interno, que resulta en la causa m\u00e1s com\u00fan del s\u00edndrome de v\u00e9rtigo epis\u00f3dico combinado con hipoacusia fluctuante. A pesar de un siglo de investigaciones, la etiolog\u00eda y la fisiopatolog\u00eda de la MD contin\u00faa\n siendo controversial e incompletamente entendida. Entre los factores que han contribuido a esta controversia encontramos la ausencia de (1) una prueba cl\u00ednica validada, (2) un modelo animal apropiado, y (3) un tratamiento espec\u00edfico. Sin embargo, los m\u00e9dicos pueden ayudar\n a los pacientes con MD usando una variedad de medicamentos y terapias para atacar s\u00edntomas espec\u00edficos. Dado que en general el v\u00e9rtigo de la MD es autolimitado, el resultado a largo plazo para la funci\u00f3n del balance es bueno. No se puede decir lo mismo para la disfunci\u00f3n\n auditiva de la MD.<\/jats:p>","DOI":"10.3766\/jaaa.17.1.3","type":"journal-article","created":{"date-parts":[[2008,4,22]],"date-time":"2008-04-22T23:54:28Z","timestamp":1208908468000},"page":"16-26","source":"Crossref","is-referenced-by-count":32,"title":["M\u00e9ni\u00e8re's Disease Review 2005"],"prefix":"10.3766","volume":"17","author":[{"given":"George A.","family":"Gates","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2087","container-title":["Journal of the American Academy of Audiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ingentaconnect.com\/content\/aaa\/jaaa\/2006\/00000017\/00000001\/art00003","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T23:15:11Z","timestamp":1738797311000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ingentaconnect.com\/content\/10.3766\/jaaa.17.1.3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,1,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2006,1,1]]}},"alternative-id":["1050-0545(20060101)17:1L.16;1-"],"URL":"https:\/\/doi.org\/10.3766\/jaaa.17.1.3","relation":{},"ISSN":["1050-0545"],"issn-type":[{"value":"1050-0545","type":"print"}],"subject":[],"published":{"date-parts":[[2006,1,1]]}}}