{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T05:00:08Z","timestamp":1761973208908,"version":"build-2065373602"},"reference-count":40,"publisher":"Society for Clinical Epidemiology","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Clin Epidemiol","ACE"],"published-print":{"date-parts":[[2025,10,31]]},"DOI":"10.37737\/ace.25016","type":"journal-article","created":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T18:07:18Z","timestamp":1747159638000},"page":"128-136","source":"Crossref","is-referenced-by-count":0,"title":["Japan Intensive Care Consortium: Nationwide Effort for Extracorporeal Membrane Oxygenation Care Optimization and Excellence Study: Study Protocol"],"prefix":"10.37737","volume":"7","author":[{"given":"Daisuke","family":"Kasugai","sequence":"first","affiliation":[{"name":"Department of Emergency and Critical Care Medicine, Nagoya University Graduate School of Medicine"},{"name":"Institute of Nano-Life-Systems, Institutes of Innovation for Future Society, Nagoya University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryohei","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Center for Innovative Research for Communities and Clinical Excellence (CIRC2LE), Fukushima Medical University"},{"name":"Section of Clinical Epidemiology, Department of Community Medicine, Kyoto University Graduate School of Medicine"},{"name":"Department of Intensive Care Medicine, Kameda Medical Center, Kamogawa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirotada","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Medicine, Kameda Medical Center, Kamogawa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takayuki","family":"Owaki","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine, Nagoya University Graduate School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mei","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine, Nagoya University Graduate School of Medicine"},{"name":"Nagoya University School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junta","family":"Honda","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine, Nagoya University Graduate School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taisuke","family":"Isomoto","sequence":"additional","affiliation":[{"name":"Department of Clinical Engineering, Hyogo Medical University Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiromu","family":"Okano","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, St. Luke\u2019s International Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeo","family":"Matsumoto","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University"},{"name":"Department of Emergency Medicine, Aki Ota Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taiga","family":"Sunada","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Nara Prefecture General Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Kawauchi","sequence":"additional","affiliation":[{"name":"Department of Critical Care and Emergency Medicine Japanese Red Cross Maebashi Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuo","family":"Kajino","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Nara Prefecture General Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaki","family":"Shiba","sequence":"additional","affiliation":[{"name":"Department of Clinical Engineering, Showa University Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takuma","family":"Ohi","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Ogaki Municipal Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshio","family":"Funahashi","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine, Nagoya University Graduate School of Medicine"},{"name":"Department of Nephrology, Nagoya University Graduate School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seiya","family":"Sato","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular rehabilitation, National cerebral and Cardiovascular Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinya","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation, Nagoya University Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroki","family":"Sato","sequence":"additional","affiliation":[{"name":"Faculty of Rehabilitation, Kawasaki University of Medical Welfare"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Hongo","sequence":"additional","affiliation":[{"name":"Department of Emergency, Critical Care, and Disaster Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michihito","family":"Kyo","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University"},{"name":"Department of Radiation Disaster Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenya","family":"Yarimizu","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Yamagata University School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiki","family":"Morishita","sequence":"additional","affiliation":[{"name":"Department of Clinical Engineering, Fukuoka Tokushukai Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoyuki","family":"Endo","sequence":"additional","affiliation":[{"name":"Department of Emergency and Disaster Medicine, Tohoku Medical and Pharmaceutical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoki","family":"Kanda","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Teikyo University School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Itsuro","family":"Morishima","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Ogaki Municipal Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuta","family":"Yokokawa","sequence":"additional","affiliation":[{"name":"Division of Emergency and Critical Care Medicine, Tohoku University Graduate School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taketo","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine, Yokohama City Minato Red Cross Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuya","family":"Yoshino","sequence":"additional","affiliation":[{"name":"Department of Emergency, Miyoshi Central Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshinori","family":"Maezawa","sequence":"additional","affiliation":[{"name":"Department of Emergency and Intensive Care Medicine, JA Hiroshima General Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoyuki","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Critical Care Medicine, Fujita Health University School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takanori","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine, Nagoya University Graduate School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"on behalf of the ECMO NEXT study investigators","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"24670","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Abrams D, MacLaren G, Lorusso R, Price S, Yannopoulos D, Vercaemst L, et al. Extracorporeal cardiopulmonary resuscitation in adults: evidence and implications. Intensive Care Med 2022;48:1\u201315.","DOI":"10.1007\/s00134-021-06514-y"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Rabie AA, Azzam MH, Al-Fares AA, Abdelbary A, Mufti HN, Hassan IF, et al. Implementation of new ECMO centers during the COVID-19 pandemic: experience and results from the Middle East and India. Intensive Care Med 2021;47:887\u2013895.","DOI":"10.1007\/s00134-021-06451-w"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Br\u00e9chot N, Hajage D, Kimmoun A, Demiselle J, Agerstrand C, Montero S, et al. Venoarterial extracorporeal membrane oxygenation to rescue sepsis-induced cardiogenic shock: a retrospective, multicentre, international cohort study. Lancet 2020;396:545\u2013552.","DOI":"10.1016\/S0140-6736(20)30733-9"},{"key":"4","doi-asserted-by":"publisher","unstructured":"4. Thiele H, M\u00f8ller JE, Henriques JPS, Bogerd M, Seyfarth M, Burkhoff D, et al. Temporary mechanical circulatory support in infarct-related cardiogenic shock: an individual patient data meta-analysis of randomised trials with 6-month follow-up. Lancet 2024;404:1019\u20131028.","DOI":"10.1016\/S0140-6736(24)01448-X"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Ostadal P, Rokyta R, Karasek J, Kruger A, Vondrakova D, Janotka M, et al. Extracorporeal membrane oxygenation in the therapy of cardiogenic shock: results of the ECMO-CS randomized clinical trial. Circulation 2023;147:454\u2013464.","DOI":"10.1161\/CIRCULATIONAHA.122.062949"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Friedrichson B, Mutlak H, Zacharowski K, Piekarski F. Insight into ECMO, mortality and ARDS: a nationwide analysis of 45,647 ECMO runs. Crit Care 2021;25:38.","DOI":"10.1186\/s13054-021-03463-2"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Martucci G, Giani M, Schmidt M, Tanaka K, Tabatabai A, Tuzzolino F, et al. Anticoagulation and bleeding during veno-venous extracorporeal membrane oxygenation: insights from the PROTECMO study. Am J Respir Crit Care Med 2024;209:417\u2013426.","DOI":"10.1164\/rccm.202305-0896OC"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Nunez JI, Gosling AF, O\u2019Gara B, Kennedy KF, Rycus P, Abrams D, et al. Bleeding and thrombotic events in adults supported with venovenous extracorporeal membrane oxygenation: an ELSO registry analysis. Intensive Care Med 2022;48:213\u2013224.","DOI":"10.1007\/s00134-021-06593-x"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Ait Hssain A, Vahedian-Azimi A, Ibrahim AS, Hassan IF, Azoulay E, Darmon M. Incidence, risk factors and outcomes of nosocomial infection in adult patients supported by extracorporeal membrane oxygenation: a systematic review and meta-analysis. Crit Care 2024;28:158.","DOI":"10.1186\/s13054-024-04946-8"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Thiagarajan RR, Barbaro RP, Rycus PT, McMullan DM, Conrad SA, Fortenberry JD, et al. Extracorporeal life support organization registry international report 2016. ASAIO J 2017;63:60\u201367.","DOI":"10.1097\/MAT.0000000000000475"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Inoue A, Hifumi T, Sakamoto T, Okamoto H, Kunikata J, Yokoi H, et al. Extracorporeal cardiopulmonary resuscitation in adult patients with out-of-hospital cardiac arrest: a retrospective large cohort multicenter study in Japan. Crit Care 2022;26:129.","DOI":"10.1186\/s13054-022-03998-y"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Nishikimi M, Ohshimo S, Fukumoto W, Hamaguchi J, Matsumura K, Fujizuka K, et al. Chest CT findings in severe acute respiratory distress syndrome requiring V-V ECMO: J-CARVE registry. J Intensive Care 2024;12:5.","DOI":"10.1186\/s40560-023-00715-x"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Sun K, Yao C, Xu G, Wang J, Shou S, Jin H. Research progress on the pathogenesis of AKI complicated by ECMO. Clin Exp Nephrol 2025;29:10\u201320.","DOI":"10.1007\/s10157-024-02559-7"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Polastri M, Eden A, Swol J. Rehabilitation for adult patients undergoing extracorporeal membrane oxygenation. Perfusion 2024;39(suppl 1):115S\u2013126S.","DOI":"10.1177\/02676591231226289"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Thangappan K, Cavarocchi NC, Baram M, Thoma B, Hirose H. Systemic inflammatory response syndrome (SIRS) after extracorporeal membrane oxygenation (ECMO): incidence, risks and survivals. Heart Lung 2016;45:449\u2013453.","DOI":"10.1016\/j.hrtlng.2016.06.004"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Squiccimarro E, Labriola C, Malvindi PG, Margari V, Guida P, Visicchio G, et al. Prevalence and clinical impact of systemic inflammatory reaction after cardiac surgery. J Cardiothorac Vasc Anesth 2019;33:1682\u20131690.","DOI":"10.1053\/j.jvca.2019.01.043"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Busch M, Seeliger B, Fuge J, Hoeper MM, Stahl K, Post-ECMO-Fever Research Group. Fever or hypothermia following ECMO decannulation: the association of body temperature with survival. Crit Care 2024;28:13.","DOI":"10.1186\/s13054-023-04790-2"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Mahajan R, Burza S, Bouter LM, Sijtsma K, Knottnerus A, Kleijnen J, et al. Standardized Protocol Items Recommendations for Observational Studies (SPIROS) observational study protocol reporting guidelines: protocol for a Delphi Study. JMIR Res Protoc 2020;9:e17864.","DOI":"10.2196\/17864"},{"key":"19","unstructured":"19. Japanese Society of Intensive Care Medicine U35 project. Available from: https:\/\/www.jsicm.org\/commitee\/U35\/, Accessed 2025 Jan 27."},{"key":"20","unstructured":"20. Japanese Society of Education for Physicians and Trainees. Japanese Society of Education for Physicians and Trainees in intensive care clinical trial group. Available from: https:\/\/www.jseptic.com\/en\/aboutctg.html, Accessed 2025 Jan 27."},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Hern\u00e1n MA. Causal analyses of existing databases: no power calculations required. J Clin Epidemiol 2022;144:203\u2013205.","DOI":"10.1016\/j.jclinepi.2021.08.028"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Harris PA, Taylor R, Thielke R, Payne J, Gonzalez N, Conde JG. Research Electronic Data Capture (REDCap)\u2014a metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform 2009;42:377\u2013381.","DOI":"10.1016\/j.jbi.2008.08.010"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Schmidt M, Burrell A, Roberts L, Bailey M, Sheldrake J, Rycus PT, et al. Predicting survival after ECMO for refractory cardiogenic shock: the survival after veno-arterial-ECMO (SAVE)-score. Eur Heart J 2015;36:2246\u20132256.","DOI":"10.1093\/eurheartj\/ehv194"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Schmidt M, Bailey M, Sheldrake J, Hodgson C, Aubron C, Rycus PT, et al. Predicting survival after extracorporeal membrane oxygenation for severe acute respiratory failure. The Respiratory Extracorporeal Membrane Oxygenation Survival Prediction (RESP) score. Am J Respir Crit Care Med 2014;189:1374\u20131382.","DOI":"10.1164\/rccm.201311-2023OC"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Buetti N, Zahar JR, Adda M, Ruckly S, Bruel C, Schwebel C, et al. Treatment of positive catheter tip culture without bloodstream infections in critically ill patients. A case-cohort study from the OUTCOMEREA network. Intensive Care Med 2024;50:1108\u20131118.","DOI":"10.1007\/s00134-024-07498-1"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Martin-Loeches I, Povoa P, Rodr\u00edguez A, Curcio D, Suarez D, Mira JP, et al. Incidence and prognosis of ventilator-associated tracheobronchitis (TAVeM): a multicentre, prospective, observational study. Lancet Respir Med 2015;3:859\u2013868.","DOI":"10.1016\/S2213-2600(15)00326-4"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Chastre J, Fagon JY. Ventilator-associated pneumonia. Am J Respir Crit Care Med 2002;165:867\u2013903.","DOI":"10.1164\/ajrccm.165.7.2105078"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. Qin X, Zhao H, Qin W, Qin X, Shen S, Wang H. Efficacy of expanded periurethral cleansing in reducing catheter-associated urinary tract infection in comatose patients: a randomized controlled clinical trial. Crit Care 2024;28:162.","DOI":"10.1186\/s13054-024-04947-7"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29. Chenoweth CE, Gould CV, Saint S. Diagnosis, management, and prevention of catheter-associated urinary tract infections. Infect Dis Clin North Am 2014;28:105\u2013119.","DOI":"10.1016\/j.idc.2013.09.002"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30. Hedberg P, Ternhag A, Giske CG, Str\u00e5lin K, \u00d6zenci V, Johansson N, et al. Ventilator-associated lower respiratory tract bacterial infections in COVID-19 compared with non-COVID-19 patients. Crit Care Med 2022;50:825\u2013836.","DOI":"10.1097\/CCM.0000000000005462"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31. Ostermann M, Bellomo R, Burdmann EA, Doi K, Endre ZH, Goldstein SL, et al. Controversies in acute kidney injury: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference. Kidney Int 2020;98:294\u2013309.","DOI":"10.1016\/j.kint.2020.04.020"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32. Kumble S, McLaughlin KH, Funk K, Dekany S, Ludwig D, Farley H, et al. Development of a new tool to combine the promotion of patient mobility with safe patient handling equipment: the Johns Hopkins Safe patient handling mobility (JH-SPHM) guide. Workplace Health Saf 2024;72:503\u2013513.","DOI":"10.1177\/21650799241268745"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33. Nakanishi N, Liu K, Kawauchi A, Okamura M, Tanaka K, Katayama S, et al. Instruments to assess post-intensive care syndrome assessment: a scoping review and modified Delphi method study. Crit Care 2023;27:430.","DOI":"10.1186\/s13054-023-04681-6"},{"key":"34","doi-asserted-by":"crossref","unstructured":"34. Tipping CJ, Bailey MJ, Bellomo R, Berney S, Buhr H, Denehy L, et al. The ICU mobility scale has construct and predictive validity and is responsive. A multicenter observational study. Ann Am Thorac Soc 2016;13:887\u2013893.","DOI":"10.1513\/AnnalsATS.201510-717OC"},{"key":"35","doi-asserted-by":"crossref","unstructured":"35. Church S, Rogers E, Rockwood K, Theou O. A scoping review of the Clinical Frailty Scale. BMC Geriatr 2020;20:393.","DOI":"10.1186\/s12877-020-01801-7"},{"key":"36","doi-asserted-by":"crossref","unstructured":"36. White KC, Serpa-Neto A, Hurford R, Clement P, Laupland KB, See E, et al. Sepsis-associated acute kidney injury in the intensive care unit: incidence, patient characteristics, timing, trajectory, treatment, and associated outcomes. A multicenter, observational study. Intensive Care Med 2023;49:1079\u20131089.","DOI":"10.1007\/s00134-023-07138-0"},{"key":"37","doi-asserted-by":"crossref","unstructured":"37. Wakefield CJ, Jochum SB, Hejna EE, Peterson SB, Vines DL, Shah PN, et al. Respiratory musculature evaluated by computed tomography in the setting of prolonged mechanical ventilation. Respir Care 2023;68:1106\u20131111.","DOI":"10.4187\/respcare.09491"},{"key":"38","doi-asserted-by":"crossref","unstructured":"38. Tolonen A, Pakarinen T, Sassi A, Kytt\u00e4 J, Cancino W, Rinta-Kiikka I, et al. Methodology, clinical applications, and future directions of body composition analysis using computed tomography (CT) images: a review. Eur J Radiol 2021;145:109943.","DOI":"10.1016\/j.ejrad.2021.109943"},{"key":"39","doi-asserted-by":"crossref","unstructured":"39. Antonucci E, Garcia B, Chen D, Matthay MA, Liu KD, Legrand M. Incidence of acute kidney injury and attributive mortality in acute respiratory distress syndrome randomized trials. Intensive Care Med 2024;50:1240\u20131250.","DOI":"10.1007\/s00134-024-07485-6"},{"key":"40","doi-asserted-by":"crossref","unstructured":"40. Chesnaye NC, Stel VS, Tripepi G, Dekker FW, Fu EL, Zoccali C, et al. An introduction to inverse probability of treatment weighting in observational research. Clin Kidney J 2021;15:14\u201320.","DOI":"10.1093\/ckj\/sfab158"}],"container-title":["Annals of Clinical Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/ace\/7\/4\/7_25016\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T04:27:20Z","timestamp":1761971240000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/ace\/7\/4\/7_25016\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,31]]},"references-count":40,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.37737\/ace.25016","relation":{},"ISSN":["2434-4338"],"issn-type":[{"type":"electronic","value":"2434-4338"}],"subject":[],"published":{"date-parts":[[2025,10,31]]},"article-number":"25016"}}