{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T16:38:00Z","timestamp":1792687080751,"version":"4.5.0"},"reference-count":11,"publisher":"MyJove Corporation","issue":"104","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JoVE"],"DOI":"10.3791\/52750","type":"journal-article","created":{"date-parts":[[2015,10,19]],"date-time":"2015-10-19T20:00:10Z","timestamp":1445284810000},"source":"Crossref","is-referenced-by-count":6,"title":["Culturing Mouse Cardiac Valves in the Miniature Tissue Culture System"],"prefix":"10.3791","author":[{"given":"Boudewijn P.T.","family":"Kruithof","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel C.","family":"Lieber","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianna","family":"Kruithof-de Julio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincian","family":"Gaussin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie Jos\u00e9","family":"Goumans","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2098","published-online":{"date-parts":[[2015,10,19]]},"reference":[{"key":"ref1","first-page":"e28","type":"journal-article","article-title":"Heart Disease and Stroke Statistics--2014 Update: A Report From the American Heart Association","volume":"129","author":"Go","year":"2013","unstructured":"Go, A. S. et al. Heart Disease and Stroke Statistics--2014 Update: A Report From the American Heart Association. Circulation. 129, e28\u2013292, doi:10.1161\/01.cir.0000441139.02102.80 (2013).","journal-title":"Circulation"},{"issue":"2","key":"ref2","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1161\/CIRCRESAHA.112.300154","type":"journal-article","article-title":"Hemodynamic and Cellular Response Feedback in Calcific Aortic Valve Disease","volume":"113","author":"Gould","year":"2013","unstructured":"Gould, S. T., Srigunapalan, S., Simmons, C. a., & Anseth, K. S. Hemodynamic and Cellular Response Feedback in Calcific Aortic Valve Disease. Circulation Research. 113 (2), 186\u2013197, doi:10.1161\/CIRCRESAHA.112.300154 (2013).","journal-title":"Circulation Research"},{"issue":"1","key":"ref3","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.ydbio.2006.09.024","type":"journal-article","article-title":"Atrioventricular valve development during late embryonic and postnatal stages involves condensation and extracellular matrix remodeling","volume":"302","author":"Kruithof","year":"2007","unstructured":"Kruithof, B. P. T., Krawitz, S. a & Gaussin, V. Atrioventricular valve development during late embryonic and postnatal stages involves condensation and extracellular matrix remodeling. Developmental biology. 302 (1), 208\u201317, doi:10.1016\/j.ydbio.2006.09.024 (2007).","journal-title":"Developmental biology"},{"issue":"4","key":"ref4","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.carpath.2005.03.005","type":"journal-article","article-title":"Cardiac valves and valvular pathology: update on function, disease, repair, and replacement","volume":"14","author":"Schoen","year":"2005","unstructured":"Schoen, F. J. Cardiac valves and valvular pathology: update on function, disease, repair, and replacement. Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology. 14 (4), 189\u201394, doi:10.1016\/j.carpath.2005.03.005 (2005).","journal-title":"Cardiovascular pathology: the official journal of the Society for Cardiovascular Pathology"},{"key":"ref5","first-page":"263870","type":"journal-article","article-title":"Hemodynamics and mechanobiology of aortic valve inflammation and calcification","author":"Balachandran","year":"2011","unstructured":"Balachandran, K., Sucosky, P., & Yoganathan, A. P. Hemodynamics and mechanobiology of aortic valve inflammation and calcification. International journal of inflammation., 263870, doi:10.4061\/2011\/263870 (2011).","journal-title":"International journal of inflammation"},{"issue":"1","key":"ref6","first-page":"62","type":"journal-article","article-title":"Mechanobiology of the Aortic Heart Valve","volume":"17","author":"Butcher","year":"2008","unstructured":"Butcher, J. T., Simmons, C. A., & Warnock, J. N. Mechanobiology of the Aortic Heart Valve. The Journal of heart valve disease. 17 (1), 62-73 (2008).","journal-title":"The Journal of heart valve disease"},{"issue":"11","key":"ref7","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1007\/s10439-006-9167-8","type":"journal-article","article-title":"An ex vivo study of the biological properties of porcine aortic valves in response to circumferential cyclic stretch","volume":"34","author":"Balachandran","year":"2006","unstructured":"Balachandran, K., Konduri, S., Sucosky, P., Jo, H., & Yoganathan, A. P. An ex vivo study of the biological properties of porcine aortic valves in response to circumferential cyclic stretch. Annals of biomedical engineering. 34 (11), 1655\u201365, doi:10.1007\/s10439-006-9167-8 (2006).","journal-title":"Annals of biomedical engineering"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1016\/j.jbiomech.2011.03.017","type":"journal-article","article-title":"Regional analysis of dynamic deformation characteristics of native aortic valve leaflets","volume":"44","author":"Weiler","year":"2011","unstructured":"Weiler, M., Hwai Yap, C., Balachandran, K., Padala, M., & Yoganathan, A. P. Regional analysis of dynamic deformation characteristics of native aortic valve leaflets. Journal of Biomechanics. 44, 1459\u20131465, doi:10.1016\/j.jbiomech.2011.03.017 (2011).","journal-title":"Journal of Biomechanics"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1161\/CIRCRESAHA.109.201566","type":"journal-article","article-title":"Heart valve development: Regulatory networks in development and disease","volume":"105","author":"Combs","year":"2009","unstructured":"Combs, M. D., & Yutzey, K. E. Heart valve development: Regulatory networks in development and disease. Circulation Research. 105, 408\u2013421, doi:10.1161\/CIRCRESAHA.109.201566 (2009).","journal-title":"Circulation Research"},{"issue":"1","key":"ref10","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.diff.2012.04.003","type":"journal-article","article-title":"TGF\u03b2 and BMP signaling in cardiac cushion formation: lessons from mice and chicken","volume":"84","author":"Kruithof","year":"2012","unstructured":"Kruithof, B. P. T., Duim, S. N., Moerkamp, A. T., & Goumans, M.-J. TGF\u03b2 and BMP signaling in cardiac cushion formation: lessons from mice and chicken. Differentiation; research in biological diversity. 84 (1), 89\u2013102, doi:10.1016\/j.diff.2012.04.003 (2012).","journal-title":"Differentiation; research in biological diversity"},{"issue":"3","key":"ref11","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1007\/s10439-010-9922-8","type":"journal-article","article-title":"Design of a miniature tissue culture system to culture mouse heart valves","volume":"38","author":"Lieber","year":"2010","unstructured":"Lieber, S. C., Kruithof, B. P. T., Aubry, N., Vatner, S. F., & Gaussin, V. Design of a miniature tissue culture system to culture mouse heart valves. Annals of biomedical engineering. 38 (3), 674\u201382, doi:10.1007\/s10439-010-9922-8 (2010).","journal-title":"Annals of biomedical engineering"}],"container-title":["Journal of Visualized Experiments"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.jove.com\/video\/52750\/culturing-mouse-cardiac-valves-in-the-miniature-tissue-culture-system","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T15:45:24Z","timestamp":1792683924000},"score":1,"resource":{"primary":{"URL":"https:\/\/app.jove.com\/t\/52750"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10,19]]},"references-count":11,"journal-issue":{"issue":"104","published-online":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.3791\/52750","relation":{},"ISSN":["1940-087X"],"issn-type":[{"value":"1940-087X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,10,19]]}}}