{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T22:43:00Z","timestamp":1792622580040,"version":"4.5.0"},"reference-count":15,"publisher":"MyJove Corporation","issue":"163","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JoVE"],"DOI":"10.3791\/61508","type":"journal-article","created":{"date-parts":[[2020,9,10]],"date-time":"2020-09-10T20:01:01Z","timestamp":1599768061000},"source":"Crossref","is-referenced-by-count":2,"title":["Exosome Isolation after in vitro Shock Wave Therapy"],"prefix":"10.3791","author":[{"given":"Leo","family":"P\u00f6lzl","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"N\u00e4gele","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakob","family":"Hirsch","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Graber","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Grimm","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Can","family":"Gollmann-Tepek\u00f6yl\u00fc","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Holfeld","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2098","published-online":{"date-parts":[[2020,9,10]]},"reference":[{"issue":"1","key":"ref1","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1056\/NEJMct1103074","type":"journal-article","article-title":"Shock-wave lithotripsy for renal calculi","volume":"367","author":"Pearle","year":"2012","unstructured":"Pearle, M.S. et al. Shock-wave lithotripsy for renal calculi. The New England Journal of Medicine. 367 (1), 50-7 (2012).","journal-title":"The New England Journal of Medicine"},{"issue":"8207","key":"ref2","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1016\/S0140-6736(80)92335-1","type":"journal-article","article-title":"Extracorporeally Induced Destruction of Kidney Stones By Shock Waves","volume":"316","author":"Chaussy","year":"1980","unstructured":"Chaussy, C., Brendel, W., Schmiedt, E. Extracorporeally Induced Destruction of Kidney Stones By Shock Waves. Lancet. 316 (8207), 1265-8 (1980).","journal-title":"Lancet"},{"issue":"3","key":"ref3","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/BF00192289","type":"journal-article","article-title":"High energy shock waves in the treatment of delayed and nonunion of fractures","volume":"15","author":"Valchanou","year":"1991","unstructured":"Valchanou, V.D., Michailov, P. High energy shock waves in the treatment of delayed and nonunion of fractures. International Orthopedics. 15 (3), 181-4 (1991).","journal-title":"International Orthopedics"},{"issue":"6","key":"ref4","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/0090-4295(92)90009-L","type":"journal-article","article-title":"Influence of shock waves on fracture healing","volume":"39","author":"Haupt","year":"1992","unstructured":"Haupt, G., Haupt, A., Ekkernkamp, A., Gerety, B., Chvapil, M. Influence of shock waves on fracture healing. Urology. 39 (6), 529-32 (1992).","journal-title":"Urology"},{"issue":"2","key":"ref5","first-page":"155","type":"journal-article","article-title":"Bone healing induced by ESWT","volume":"6","author":"Moretti","year":"2009","unstructured":"Moretti, B. et al. Bone healing induced by ESWT. Clinical Cases in Mineral and Bone Metabolism. 6 (2), 155-8 (2009).","journal-title":"Clinical Cases in Mineral and Bone Metabolism"},{"issue":"1","key":"ref6","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1159\/000355472","type":"journal-article","article-title":"Extracorporeal shock wave therapy in musculoskeletal disorders: A review","volume":"23","author":"Romeo","year":"2014","unstructured":"Romeo, P., Lavanga, V., Pagani, D., Sansone, V. Extracorporeal shock wave therapy in musculoskeletal disorders: A review. Medical Principles and Practice. 23 (1), 7-13 (2014).","journal-title":"Medical Principles and Practice"},{"issue":"1","key":"ref7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jss.2007.01.009","type":"journal-article","article-title":"Shock Wave Therapy for Acute and Chronic Soft Tissue Wounds: A Feasibility Study","volume":"143","author":"Schaden","year":"2007","unstructured":"Schaden, W. et al. Shock Wave Therapy for Acute and Chronic Soft Tissue Wounds: A Feasibility Study. Journal of Surgical Research. 143 (1), 1-12 (2007).","journal-title":"Journal of Surgical Research"},{"issue":"8","key":"ref8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0103982","type":"journal-article","article-title":"Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation","volume":"9","author":"Holfeld","year":"2014","unstructured":"Holfeld, J. et al. Low energy shock wave therapy induces angiogenesis in acute hind-limb ischemia via VEGF receptor 2 phosphorylation. PLoS One. 9 (8), 1-7 (2014).","journal-title":"PLoS One"},{"issue":"4","key":"ref9","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1016\/j.jtcvs.2008.11.006","type":"journal-article","article-title":"Direct epicardial shock wave therapy improves ventricular function and induces angiogenesis in ischemic heart failure","volume":"137","author":"Zimpfer","year":"2009","unstructured":"Zimpfer, D. et al. Direct epicardial shock wave therapy improves ventricular function and induces angiogenesis in ischemic heart failure. Journal of Thoracic and Cardiovascular Surgery. 137 (4), 963-70 (2009).","journal-title":"Journal of Thoracic and Cardiovascular Surgery"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1002\/term.1890","type":"journal-article","article-title":"Epicardial shock-wave therapy improves ventricular function in a porcine model of ischemic heart disease","volume":"10","author":"Holfeld","year":"2016","unstructured":"Holfeld, J. et al. Epicardial shock-wave therapy improves ventricular function in a porcine model of ischemic heart disease. Journal of Tissue Engineering and Regenerative Medicine. 10, 1057-1064 (2016).","journal-title":"Journal of Tissue Engineering and Regenerative Medicine"},{"issue":"2","key":"ref11","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1093\/cvr\/cvv272","type":"journal-article","article-title":"Toll-like receptor 3 signaling mediates angiogenic response upon shock wave treatment of ischemic muscle","volume":"109","author":"Holfeld","year":"2016","unstructured":"Holfeld, J. et al. Toll-like receptor 3 signaling mediates angiogenic response upon shock wave treatment of ischemic muscle. Cardiovascular Research. 109 (2), 331-43 (2016).","journal-title":"Cardiovascular Research"},{"issue":"4","key":"ref12","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1111\/jcmm.13021","type":"journal-article","article-title":"Shockwaves prevent from heart failure after acute myocardial ischemia via RNA\/protein complexes","volume":"21","author":"Tepek\u00f6yl\u00fc","year":"2017","unstructured":"Tepek\u00f6yl\u00fc, C. et al. Shockwaves prevent from heart failure after acute myocardial ischemia via RNA\/protein complexes. Journal of Cellular and Molecular Medicine. 21 (4), 791-801 (2017).","journal-title":"Journal of Cellular and Molecular Medicine"},{"key":"ref13","type":"journal-article","article-title":"miR-19a-3p containing exosomes improve function of ischemic myocardium upon shock wave therapy","author":"Gollmann-Tepek\u00f6yl\u00fc","year":"2019","unstructured":"Gollmann-Tepek\u00f6yl\u00fc, C. et al. miR-19a-3p containing exosomes improve function of ischemic myocardium upon shock wave therapy. Cardiovascular Research. (2019).","journal-title":"Cardiovascular Research"},{"issue":"1","key":"ref14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13063-020-04369-0","type":"journal-article","article-title":"Safety and efficacy of direct Cardiac Shockwave Therapy in patients with ischemic cardiomyopathy undergoing coronary artery bypass grafting (the CAST-HF trial), Study protocol for a randomized controlled trial","volume":"21","author":"P\u00f6lzl","year":"2020","unstructured":"P\u00f6lzl, L. et al. Safety and efficacy of direct Cardiac Shockwave Therapy in patients with ischemic cardiomyopathy undergoing coronary artery bypass grafting (the CAST-HF trial), Study protocol for a randomized controlled trial. Trials. 21 (1), 1-10 (2020).","journal-title":"Trials"},{"issue":"86","key":"ref15","first-page":"e51076","type":"journal-article","article-title":"Shock wave application to cell cultures","author":"Holfeld","year":"2014","unstructured":"Holfeld, J. et al. Shock wave application to cell cultures. Journal of Visualized Experiments. (86), e51076 (2014).","journal-title":"Journal of Visualized Experiments"}],"container-title":["Journal of Visualized Experiments"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jove.com\/t\/61508\/exosome-isolation-after-in-vitro-shock-wave-therapy","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T22:34:47Z","timestamp":1792622087000},"score":1,"resource":{"primary":{"URL":"https:\/\/app.jove.com\/t\/61508"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,10]]},"references-count":15,"journal-issue":{"issue":"163","published-online":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.3791\/61508","relation":{},"ISSN":["1940-087X"],"issn-type":[{"value":"1940-087X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,10]]}}}