{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T22:43:01Z","timestamp":1792622581738,"version":"4.5.0"},"reference-count":14,"publisher":"MyJove Corporation","issue":"163","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JoVE"],"DOI":"10.3791\/61546","type":"journal-article","created":{"date-parts":[[2020,9,3]],"date-time":"2020-09-03T20:00:24Z","timestamp":1599163224000},"source":"Crossref","is-referenced-by-count":0,"title":["Delayed Intramyocardial Delivery of Stem Cells after Ischemia Reperfusion Injury in a Murine Model"],"prefix":"10.3791","author":[{"given":"Michaela","family":"Olthoff","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Franchi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen  M.","family":"Peterson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramasamy","family":"Paulmurugan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Rodriguez-Porcel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2098","published-online":{"date-parts":[[2020,9,3]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","DOI":"10.1007\/s11307-019-01470-y","type":"journal-article","article-title":"The Myocardial Microenvironment Modulates the Biology of Transplanted Mesenchymal Stem Cells","author":"Franchi","year":"2020","unstructured":"Franchi, F. et al. The Myocardial Microenvironment Modulates the Biology of Transplanted Mesenchymal Stem Cells. Molecular Imaging Biology. 10.1007\/s11307-019-01470-y (2020).","journal-title":"Molecular Imaging Biology"},{"issue":"5923","key":"ref2","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1126\/science.1164680","type":"journal-article","article-title":"Evidence for cardiomyocyte renewal in humans","volume":"324","author":"Bergmann","year":"2009","unstructured":"Bergmann, O. et al. Evidence for cardiomyocyte renewal in humans. Science. 324 (5923), 98-102 (2009).","journal-title":"Science"},{"issue":"4","key":"ref3","first-page":"38","type":"journal-article","article-title":"Heart Disease and Stroke Statistics-2016 Update: A Report From the American Heart Association","volume":"133","year":"2016","unstructured":"Writing Group, M. et al. Heart Disease and Stroke Statistics-2016 Update: A Report From the American Heart Association. Circulation. 133 (4), e38-360 (2016).","journal-title":"Circulation"},{"issue":"10","key":"ref4","doi-asserted-by":"crossref","first-page":"876","DOI":"10.4065\/84.10.876","type":"journal-article","article-title":"Cardiac cell repair therapy: a clinical perspective","volume":"84","author":"Gersh","year":"2009","unstructured":"Gersh, B. J., Simari, R. D., Behfar, A., Terzic, C. M., Terzic, A. Cardiac cell repair therapy: a clinical perspective. Mayo Clinic Protocol. 84 (10), 876-892 (2009).","journal-title":"Mayo Clinic Protocol"},{"issue":"19","key":"ref5","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1093\/eurheartj\/ehu117","type":"journal-article","article-title":"Regenerative heart failure therapy headed for optimization","volume":"35","author":"Terzic","year":"2014","unstructured":"Terzic, A., Behfar, A. Regenerative heart failure therapy headed for optimization. European Heart Journal. 35 (19), 1231-1234 (2014).","journal-title":"European Heart Journal"},{"issue":"6","key":"ref6","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1002\/stem.1976","type":"journal-article","article-title":"Hypoxic preconditioning of mesenchymal stromal cells induces metabolic changes, enhances survival, and promotes cell retention in vivo","volume":"33","author":"Beegle","year":"2015","unstructured":"Beegle, J. et al. Hypoxic preconditioning of mesenchymal stromal cells induces metabolic changes, enhances survival, and promotes cell retention in vivo. Stem Cells. 33 (6), 1818-1828 (2015).","journal-title":"Stem Cells"},{"issue":"9","key":"ref7","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1161\/CIRCRESAHA.112.265819","type":"journal-article","article-title":"Mitochondria and mitophagy: the yin and yang of cell death control","volume":"111","author":"Kubli","year":"2012","unstructured":"Kubli, D. A., Gustafsson, A. B. Mitochondria and mitophagy: the yin and yang of cell death control. Circulation Research. 111 (9), 1208-1221 (2012).","journal-title":"Circulation Research"},{"issue":"7","key":"ref8","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/j.jcmg.2012.11.018","type":"journal-article","article-title":"Noninvasive monitoring of oxidative stress in transplanted mesenchymal stromal cells","volume":"6","author":"Psaltis","year":"2013","unstructured":"Psaltis, P. J. et al. Noninvasive monitoring of oxidative stress in transplanted mesenchymal stromal cells. JACC Cardiovascular Imaging. 6 (7), 795-802 (2013).","journal-title":"JACC Cardiovascular Imaging"},{"issue":"6","key":"ref9","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1093\/cvr\/cvz336","type":"journal-article","article-title":"Cardiac monocytes and macrophages after myocardial infarction","volume":"16","author":"Peet","year":"2020","unstructured":"Peet, C., Ivetic, A., Bromage, D. I., Shah, A. M. Cardiac monocytes and macrophages after myocardial infarction. Cardiovasc Research. 16 (6), 1101-1112 (2020).","journal-title":"Cardiovasc Research"},{"issue":"12","key":"ref10","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1038\/s41577-018-0065-8","type":"journal-article","article-title":"Cardioimmunology: the immune system in cardiac homeostasis and disease","volume":"18","author":"Swirski","year":"2018","unstructured":"Swirski, F. K., Nahrendorf, M. Cardioimmunology: the immune system in cardiac homeostasis and disease. Nature Reviews Immunology. 18 (12), 733-744 (2018).","journal-title":"Nature Reviews Immunology"},{"issue":"5","key":"ref11","doi-asserted-by":"crossref","first-page":"014397","DOI":"10.1161\/JAHA.119.014397","type":"journal-article","article-title":"Mesenchymal Stem Cells Promote the Resolution of Cardiac Inflammation After Ischemia Reperfusion Via Enhancing Efferocytosis of Neutrophils","volume":"9","author":"Zhang","year":"2020","unstructured":"Zhang, Z. et al. Mesenchymal Stem Cells Promote the Resolution of Cardiac Inflammation After Ischemia Reperfusion Via Enhancing Efferocytosis of Neutrophils. Journal of the American Heart Association. 9 (5), e014397 (2020).","journal-title":"Journal of the American Heart Association"},{"issue":"1","key":"ref12","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.trsl.2015.07.002","type":"journal-article","article-title":"Inflammation as a therapeutic target in myocardial infarction: learning from past failures to meet future challenges","volume":"167","author":"Saxena","year":"2016","unstructured":"Saxena, A., Russo, I., Frangogiannis, N. G. Inflammation as a therapeutic target in myocardial infarction: learning from past failures to meet future challenges. Translational Research. 167 (1), 152-166 (2016).","journal-title":"Translational Research"},{"issue":"1","key":"ref13","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1161\/CIRCRESAHA.116.303577","type":"journal-article","article-title":"The Biological Basis for Cardiac Repair After Myocardial Infarction: From Inflammation to Fibrosis","volume":"119","author":"Prabhu","year":"2016","unstructured":"Prabhu, S. D., Frangogiannis, N. G. The Biological Basis for Cardiac Repair After Myocardial Infarction: From Inflammation to Fibrosis. Circulation Research. 119 (1), 91-112 (2016).","journal-title":"Circulation Research"},{"issue":"4","key":"ref14","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1080\/14653240600855905","type":"journal-article","article-title":"Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement","volume":"8","author":"Dominici","year":"2006","unstructured":"Dominici, M. et al. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy. 8 (4), 315-317 (2006).","journal-title":"Cytotherapy"}],"container-title":["Journal of Visualized Experiments"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jove.com\/t\/61546\/delayed-intramyocardial-delivery-stem-cells-after-ischemia","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T22:35:36Z","timestamp":1792622136000},"score":1,"resource":{"primary":{"URL":"https:\/\/app.jove.com\/t\/61546"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,3]]},"references-count":14,"journal-issue":{"issue":"163","published-online":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.3791\/61546","relation":{},"ISSN":["1940-087X"],"issn-type":[{"value":"1940-087X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,3]]}}}