{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T20:59:23Z","timestamp":1792616363139,"version":"4.5.0"},"reference-count":24,"publisher":"MyJove Corporation","issue":"178","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JoVE"],"DOI":"10.3791\/63184","type":"journal-article","created":{"date-parts":[[2021,12,10]],"date-time":"2021-12-10T19:00:36Z","timestamp":1639162836000},"source":"Crossref","is-referenced-by-count":0,"title":["Aggravation of Myocardial Ischemia upon Particulate Matter Exposure in Atherosclerosis Animal Model"],"prefix":"10.3791","author":[{"given":"Yuanmin","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuoqiu","family":"Deng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuiqing","family":"Qu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongyuan","family":"Zheng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujie","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2098","published-online":{"date-parts":[[2021,12,10]]},"reference":[{"issue":"10","key":"ref1","first-page":"656","type":"journal-article","article-title":"Environmental determinants of cardiovascular disease: lessons learned from air pollution","volume":"17","author":"Al-Kindi","year":"2020","unstructured":"Al-Kindi, S. G., Brook, R. D., Biswal, S., Rajagopalan, S. Environmental determinants of cardiovascular disease: lessons learned from air pollution. Nature Reviews: Cardiology. 17 (10), 656-672 (2020).","journal-title":"Nature Reviews: Cardiology"},{"key":"ref2","article-title":"Ambient (outdoor) Air Pollution","volume-title":"WHO","year":"2021","unstructured":"WHO. Ambient (outdoor) Air Pollution., <https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/ambient-(outdoor)-air-quality-and-health > (2021)."},{"key":"ref3","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.envint.2014.10.005","type":"journal-article","article-title":"A review on the human health impact of airborne particulate matter","volume":"74","author":"Kim","year":"2015","unstructured":"Kim, K. H., Kabir, E., Kabir, S. A review on the human health impact of airborne particulate matter. Environment International. 74, 136-143 (2015).","journal-title":"Environment International"},{"issue":"17","key":"ref4","doi-asserted-by":"crossref","first-page":"2054","DOI":"10.1016\/j.jacc.2018.07.099","type":"journal-article","article-title":"Air pollution and cardiovascular disease: JACC State-of-the-Art Review","volume":"72","author":"Rajagopalan","year":"2018","unstructured":"Rajagopalan, S., Al-Kindi, S. G., Brook, R. D. Air pollution and cardiovascular disease: JACC State-of-the-Art Review. Journal of the American College of Cardiology. 72 (17), 2054-2070 (2018).","journal-title":"Journal of the American College of Cardiology"},{"issue":"6","key":"ref5","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.ijheh.2015.05.002","type":"journal-article","article-title":"Associations between short-term exposure to particulate matter and ultrafine particles and myocardial infarction in Augsburg, Germany","volume":"218","author":"Wolf","year":"2015","unstructured":"Wolf, K. et al. Associations between short-term exposure to particulate matter and ultrafine particles and myocardial infarction in Augsburg, Germany. International Journal of Hygiene and Environmental Health. 218 (6), 535-542 (2015).","journal-title":"International Journal of Hygiene and Environmental Health"},{"issue":"25","key":"ref6","doi-asserted-by":"crossref","first-page":"2755","DOI":"10.1161\/CIRCULATIONAHA.109.893461","type":"journal-article","article-title":"Cardiovascular effects of ambient particulate air pollution exposure","volume":"121","author":"Sun","year":"2010","unstructured":"Sun, Q., Hong, X., Wold, L. E. Cardiovascular effects of ambient particulate air pollution exposure. Circulation. 121 (25), 2755-2765 (2010).","journal-title":"Circulation"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.ejphar.2017.05.010","type":"journal-article","article-title":"Animal models of atherosclerosis","volume":"816","author":"Emini Veseli","year":"2017","unstructured":"Emini Veseli, B. et al. Animal models of atherosclerosis. European Journal of Pharmacology. 816, 3-13 (2017).","journal-title":"European Journal of Pharmacology"},{"issue":"122","key":"ref8","first-page":"e55353","type":"journal-article","article-title":"Murine Left anterior descending (LAD) coronary artery ligation: An improved and simplified model for myocardial infarction","author":"Reichert","year":"2017","unstructured":"Reichert, K. et al. Murine Left anterior descending (LAD) coronary artery ligation: An improved and simplified model for myocardial infarction. Journal of Visualized Experiments. 122, e55353 (2017).","journal-title":"Journal of Visualized Experiments"},{"issue":"8","key":"ref9","doi-asserted-by":"crossref","first-page":"4136","DOI":"10.3390\/ijerph18084136","type":"journal-article","article-title":"The acute effect of diesel exhaust particles and different fractions exposure on blood coagulation function in mice","volume":"18","author":"Lei","year":"2021","unstructured":"Lei, J. et al. The acute effect of diesel exhaust particles and different fractions exposure on blood coagulation function in mice. International Journal of Environmental Research and Public Health. 18 (8), 4136 (2021).","journal-title":"International Journal of Environmental Research and Public Health"},{"issue":"12","key":"ref10","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1161\/CIRCRESAHA.110.223925","type":"journal-article","article-title":"A novel and efficient model of coronary artery ligation and myocardial infarction in the mouse","volume":"107","author":"Gao","year":"2010","unstructured":"Gao, E. et al. A novel and efficient model of coronary artery ligation and myocardial infarction in the mouse. Circulation Research. 107 (12), 1445-1453 (2010).","journal-title":"Circulation Research"},{"issue":"5","key":"ref11","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1080\/17435390.2020.1731857","type":"journal-article","article-title":"LncRNA PEAMIR inhibits apoptosis and inflammatory response in PM2.5 exposure aggravated myocardial ischemia\/reperfusion injury as a competing endogenous RNA of miR-29b-3p","volume":"14","author":"Pei","year":"2020","unstructured":"Pei, Y. H. et al. LncRNA PEAMIR inhibits apoptosis and inflammatory response in PM2.5 exposure aggravated myocardial ischemia\/reperfusion injury as a competing endogenous RNA of miR-29b-3p. Nanotoxicology. 14 (5), 638-653 (2020).","journal-title":"Nanotoxicology"},{"issue":"3","key":"ref12","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1002\/tox.23035","type":"journal-article","article-title":"PM2.5-induced pulmonary inflammation via activating of the NLRP3\/caspase-1 signaling pathway","volume":"36","author":"Jia","year":"2021","unstructured":"Jia, H. et al. PM2.5-induced pulmonary inflammation via activating of the NLRP3\/caspase-1 signaling pathway. Environmental Toxicology. 36 (3), 298-307 (2021).","journal-title":"Environmental Toxicology"},{"issue":"1","key":"ref13","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1038\/s41572-019-0090-3","type":"journal-article","article-title":"ST-segment elevation myocardial infarction","volume":"5","author":"Vogel","year":"2019","unstructured":"Vogel, B. et al. ST-segment elevation myocardial infarction. Nature Reviews Disease Primers. 5 (1), 39 (2019).","journal-title":"Nature Reviews Disease Primers"},{"issue":"7855","key":"ref14","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1038\/s41586-021-03392-8","type":"journal-article","article-title":"The changing landscape of atherosclerosis","volume":"592","author":"Libby","year":"2021","unstructured":"Libby, P. The changing landscape of atherosclerosis. Nature. 592 (7855), 524-533 (2021).","journal-title":"Nature"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"1209307","DOI":"10.1155\/2019\/1209307","type":"journal-article","article-title":"Excessive neutrophil extracellular trap formation aggravates acute myocardial infarction injury in Apolipoprotein E deficiency mice via the ROS-dependent pathway","volume":"2019","author":"Zhou","year":"2019","unstructured":"Zhou, Z. et al. Excessive neutrophil extracellular trap formation aggravates acute myocardial infarction injury in Apolipoprotein E deficiency mice via the ROS-dependent pathway. Oxidative Medicine and Cellular Longevity. 2019, 1209307 (2019).","journal-title":"Oxidative Medicine and Cellular Longevity"},{"issue":"1","key":"ref16","doi-asserted-by":"crossref","first-page":"16601","DOI":"10.1038\/s41598-020-73608-w","type":"journal-article","article-title":"Effects on cardiac function, remodeling and inflammation following myocardial ischemia-reperfusion injury or unreperfused myocardial infarction in hypercholesterolemic APOE*3-Leiden mice","volume":"10","author":"Pluijmert","year":"2020","unstructured":"Pluijmert, N. J., Bart, C. I., Bax, W. H., Quax, P. H. A., Atsma, D. E. Effects on cardiac function, remodeling and inflammation following myocardial ischemia-reperfusion injury or unreperfused myocardial infarction in hypercholesterolemic APOE*3-Leiden mice. Scientific Reports. 10 (1), 16601 (2020).","journal-title":"Scientific Reports"},{"issue":"148","key":"ref17","first-page":"e59828","type":"journal-article","article-title":"Quantification of atherosclerosis in mice","author":"Centa","year":"2019","unstructured":"Centa, M., Ketelhuth, D. F. J., Malin, S., Gistera, A. Quantification of atherosclerosis in mice. Journal of Visualized Experiments. 148, e59828 (2019).","journal-title":"Journal of Visualized Experiments"},{"issue":"1","key":"ref18","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.brainres.2006.07.123","type":"journal-article","article-title":"Use of TTC staining for the evaluation of tissue injury in the early phases of reperfusion after focal cerebral ischemia in rats","volume":"1116","author":"Benedek","year":"2006","unstructured":"Benedek, A. et al. Use of TTC staining for the evaluation of tissue injury in the early phases of reperfusion after focal cerebral ischemia in rats. Brain Research. 1116 (1), 159-165 (2006).","journal-title":"Brain Research"},{"issue":"6","key":"ref19","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1038\/nprot.2013.055","type":"journal-article","article-title":"Imaging of neutral lipids by oil red O for analyzing the metabolic status in health and disease","volume":"8","author":"Mehlem","year":"2013","unstructured":"Mehlem, A., Hagberg, C. E., Muhl, L., Eriksson, U., Falkevall, A. Imaging of neutral lipids by oil red O for analyzing the metabolic status in health and disease. Nature Protocols. 8 (6), 1149-1154 (2013).","journal-title":"Nature Protocols"},{"issue":"157","key":"ref20","first-page":"e60844","type":"journal-article","article-title":"Repeated orotracheal intubation in mice","author":"Nelson","year":"2020","unstructured":"Nelson, A. M., Nolan, K. E., Davis, I. C. Repeated orotracheal intubation in mice. Journal of Visualized Experiments. 157, e60844 (2020).","journal-title":"Journal of Visualized Experiments"},{"issue":"6","key":"ref21","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1016\/j.jhep.2015.07.020","type":"journal-article","article-title":"Exposure to fine airborne particulate matters induces hepatic fibrosis in murine models","volume":"63","author":"Zheng","year":"2015","unstructured":"Zheng, Z. et al. Exposure to fine airborne particulate matters induces hepatic fibrosis in murine models. Journal of Hepatology. 63 (6), 1397-1404 (2015).","journal-title":"Journal of Hepatology"},{"issue":"13","key":"ref22","doi-asserted-by":"crossref","first-page":"725","DOI":"10.3109\/08958378.2013.844749","type":"journal-article","article-title":"Systemic and vascular effects of circulating diesel exhaust particulate matter","volume":"25","author":"Bai","year":"2013","unstructured":"Bai, N., van Eeden, S. F. Systemic and vascular effects of circulating diesel exhaust particulate matter. Inhalation Toxicology. 25 (13), 725-734 (2013).","journal-title":"Inhalation Toxicology"},{"issue":"5","key":"ref23","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1007\/s00204-008-0371-1","type":"journal-article","article-title":"Extrapulmonary translocation of intratracheally instilled fine and ultrafine particles via direct and alveolar macrophage-associated routes","volume":"83","author":"Furuyama","year":"2009","unstructured":"Furuyama, A., Kanno, S., Kobayashi, T., Hirano, S. Extrapulmonary translocation of intratracheally instilled fine and ultrafine particles via direct and alveolar macrophage-associated routes. Archives of Toxicology. 83 (5), 429-437 (2009).","journal-title":"Archives of Toxicology"},{"issue":"9341","key":"ref24","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1016\/S0140-6736(02)11274-8","type":"journal-article","article-title":"Air pollution and health","volume":"360","author":"Brunekreef","year":"2002","unstructured":"Brunekreef, B., Holgate, S. T. Air pollution and health. Lancet. 360 (9341), 1233-1242 (2002).","journal-title":"Lancet"}],"container-title":["Journal of Visualized Experiments"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jove.com\/t\/63184\/aggravation-myocardial-ischemia-upon-particulate-matter-exposure","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T20:36:41Z","timestamp":1792615001000},"score":1,"resource":{"primary":{"URL":"https:\/\/app.jove.com\/t\/63184"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,10]]},"references-count":24,"journal-issue":{"issue":"178","published-online":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.3791\/63184","relation":{},"ISSN":["1940-087X"],"issn-type":[{"value":"1940-087X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,10]]}}}