{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T20:41:26Z","timestamp":1792615286287,"version":"4.5.0"},"reference-count":21,"publisher":"MyJove Corporation","issue":"183","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JoVE"],"DOI":"10.3791\/63926","type":"journal-article","created":{"date-parts":[[2022,5,19]],"date-time":"2022-05-19T20:00:36Z","timestamp":1652990436000},"source":"Crossref","is-referenced-by-count":4,"title":["Time-Resolved &lt;em&gt;In Vivo&lt;\/em&gt; Measurement of Neuropeptide Dynamics by Capacitive Immunoprobe in Porcine Heart"],"prefix":"10.3791","author":[{"given":"Nicholas","family":"Kluge","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shyue-An","family":"Chan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey L.","family":"Ardell","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corey","family":"Smith","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2098","published-online":{"date-parts":[[2022,5,19]]},"reference":[{"issue":"22","key":"ref1","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1161\/CIR.0000000000000490","type":"journal-article","article-title":"Role of Biomarkers for the prevention, assessment, and management of heart failure: A scientific statement from the American Heart Association","volume":"135","author":"Chow","year":"2017","unstructured":"Chow, S. L. et al. Role of Biomarkers for the prevention, assessment, and management of heart failure: A scientific statement from the American Heart Association. Circulation. 135 (22), e1054-e1091 (2017).","journal-title":"Circulation"},{"issue":"8","key":"ref2","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1007\/s10571-010-9606-9","type":"journal-article","article-title":"Adrenal responses to stress","volume":"30","author":"Goldstein","year":"2010","unstructured":"Goldstein, D. S. Adrenal responses to stress. Cellular and Molecular Neurobiology. 30 (8), 1433-1440 (2010).","journal-title":"Cellular and Molecular Neurobiology"},{"issue":"4","key":"ref3","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1093\/oxfordjournals.eurheartj.a060526","type":"journal-article","article-title":"Prognostic value of plasma neuropeptide-Y in coronary care unit patients with and without acute myocardial infarction","volume":"15","author":"Ullman","year":"1994","unstructured":"Ullman, B., Hulting, J., Lundberg, J. M. Prognostic value of plasma neuropeptide-Y in coronary care unit patients with and without acute myocardial infarction. European Heart Journal. 15 (4), 454-461 (1994).","journal-title":"European Heart Journal"},{"issue":"2","key":"ref4","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1152\/ajpheart.2001.281.2.H813","type":"journal-article","article-title":"Angiotensin II modulates catecholamine release into interstitial fluid of canine myocardium in vivo","volume":"281","author":"Farrell","year":"2001","unstructured":"Farrell, D. M. et al. Angiotensin II modulates catecholamine release into interstitial fluid of canine myocardium in vivo. American Journal of Physiology-Heart and Circulatory Physiology. 281 (2), H813-822 (2001).","journal-title":"American Journal of Physiology-Heart and Circulatory Physiology"},{"issue":"23","key":"ref5","doi-asserted-by":"crossref","first-page":"131648","DOI":"10.1172\/jci.insight.131648","type":"journal-article","article-title":"Cardiac sympathectomy and spinal cord stimulation attenuate reflex-mediated norepinephrine release during ischemia preventing ventricular fibrillation","volume":"4","author":"Ardell","year":"2019","unstructured":"Ardell, J. L., Foreman, R. D., Armour, J. A., Shivkumar, K. Cardiac sympathectomy and spinal cord stimulation attenuate reflex-mediated norepinephrine release during ischemia preventing ventricular fibrillation. JCI Insight. 4 (23), e131648 (2019).","journal-title":"JCI Insight"},{"issue":"3","key":"ref6","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/j.1748-1716.1985.tb07671.x","type":"journal-article","article-title":"Neuropeptide Y and sympathetic control of heart contractility and coronary vascular tone","volume":"124","author":"Franco-Cereceda","year":"1985","unstructured":"Franco-Cereceda, A., Lundberg, J. M., Dahlof, C. Neuropeptide Y and sympathetic control of heart contractility and coronary vascular tone. Acta Physiologica Scandinavica. 124 (3), 361-369 (1985).","journal-title":"Acta Physiologica Scandinavica"},{"issue":"14","key":"ref7","doi-asserted-by":"crossref","first-page":"3853","DOI":"10.1113\/JP271840","type":"journal-article","article-title":"Molecular and cellular neurocardiology: development, and cellular and molecular adaptations to heart disease","volume":"594","author":"Habecker","year":"2016","unstructured":"Habecker, B. A. et al. Molecular and cellular neurocardiology: development, and cellular and molecular adaptations to heart disease. The Journal of Physiology. 594 (14), 3853-3875 (2016).","journal-title":"The Journal of Physiology"},{"issue":"11","key":"ref8","doi-asserted-by":"crossref","first-page":"135519","DOI":"10.1172\/jci.insight.135519","type":"journal-article","article-title":"Cardiac sympathetic activation circumvents high-dose beta blocker therapy in part through release of neuropeptide Y","volume":"5","author":"Hoang","year":"2020","unstructured":"Hoang, J. D., Salavatian, S., Yamaguchi, N., Swid, M. A., Vaseghi, M. Cardiac sympathetic activation circumvents high-dose beta blocker therapy in part through release of neuropeptide Y. JCI Insight. 5 (11), e135519 (2020).","journal-title":"JCI Insight"},{"key":"ref9","first-page":"311","type":"journal-article","article-title":"Effects of neuropeptides on heart rate in dogs: comparison of VIP, PHI, NPY, CGRP, and NT","volume":"255","author":"Rigel","year":"1988","unstructured":"Rigel, D. F. Effects of neuropeptides on heart rate in dogs: comparison of VIP, PHI, NPY, CGRP, and NT. American Journal of Physiology. 255 (2 Pt 2), H311-317 (1988).","journal-title":"American Journal of Physiology"},{"issue":"1","key":"ref10","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1152\/ajpheart.00674.2020","type":"journal-article","article-title":"Rapid measurement of cardiac neuropeptide dynamics by capacitive immunoprobe in the porcine heart","volume":"320","author":"Kluge","year":"2021","unstructured":"Kluge, N. et al. Rapid measurement of cardiac neuropeptide dynamics by capacitive immunoprobe in the porcine heart. American Journal of Physiology-Heart and Circulatory Physiology. 320 (1), H66-H76 (2021).","journal-title":"American Journal of Physiology-Heart and Circulatory Physiology"},{"issue":"3","key":"ref11","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1002\/1521-4109(200103)13:3<173::AID-ELAN173>3.0.CO;2-B","type":"journal-article","article-title":"Capacitive biosensors","volume":"13","author":"Berggren","year":"2001","unstructured":"Berggren, C., Bjarnason, B., Johansson, G. Capacitive biosensors. Electroanalysis. 13 (3), 173-180 (2001).","journal-title":"Electroanalysis"},{"issue":"14","key":"ref12","doi-asserted-by":"crossref","first-page":"4227","DOI":"10.1016\/j.electacta.2009.01.081","type":"journal-article","article-title":"Impedimetric immunosensors-A review","volume":"55","author":"Prodromidis","year":"2010","unstructured":"Prodromidis, M. I. Impedimetric immunosensors-A review. Electrochimica Acta. 55 (14), 4227-4233 (2010).","journal-title":"Electrochimica Acta"},{"issue":"5849","key":"ref13","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1126\/science.1147241","type":"journal-article","article-title":"Mussel-inspired surface chemistry for multifunctional coatings","volume":"318","author":"Lee","year":"2007","unstructured":"Lee, H., Dellatore, S. M., Miller, W. M., Messersmith, P. B. Mussel-inspired surface chemistry for multifunctional coatings. Science. 318 (5849), 426-430 (2007).","journal-title":"Science"},{"issue":"6","key":"ref14","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1111\/j.1471-4159.1991.tb03441.x","type":"journal-article","article-title":"Secretion of catecholamines from individual adrenal medullary chromaffin cells","volume":"56","author":"Leszczyszyn","year":"1991","unstructured":"Leszczyszyn, D. J. et al. Secretion of catecholamines from individual adrenal medullary chromaffin cells. Journal of Neurochemistry. 56 (6), 1855-1863 (1991).","journal-title":"Journal of Neurochemistry"},{"issue":"24","key":"ref15","doi-asserted-by":"crossref","first-page":"4532","DOI":"10.1021\/ac00096a021","type":"journal-article","article-title":"Rapid and selective cyclic voltammetric measurements of epinephrine and norepinephrine as a method to measure secretion from single bovine adrenal medullary cells","volume":"66","author":"Pihel","year":"1994","unstructured":"Pihel, K., Schroeder, T. J., Wightman, R. M. Rapid and selective cyclic voltammetric measurements of epinephrine and norepinephrine as a method to measure secretion from single bovine adrenal medullary cells. Analytical Chemistry. 66 (24), 4532-4537 (1994).","journal-title":"Analytical Chemistry"},{"issue":"10","key":"ref16","doi-asserted-by":"crossref","first-page":"3548","DOI":"10.1523\/JNEUROSCI.18-10-03548.1998","type":"journal-article","article-title":"Extrasynaptic vesicular transmitter release from the somata of substantia nigra neurons in rat midbrain slices","volume":"18","author":"Jaffe","year":"1998","unstructured":"Jaffe, E. H., Marty, A., Schulte, A., Chow, R. H. Extrasynaptic vesicular transmitter release from the somata of substantia nigra neurons in rat midbrain slices. The Journal of Neuroscience. 18 (10), 3548-3553 (1998).","journal-title":"The Journal of Neuroscience"},{"issue":"1","key":"ref17","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1152\/ajpcell.00332.2010","type":"journal-article","article-title":"Distinguishing splanchnic nerve and chromaffin cell stimulation in mouse adrenal slices with fast-scan cyclic voltammetry","volume":"300","author":"Walsh","year":"2011","unstructured":"Walsh, P. L., Petrovic, J., Wightman, R. M. Distinguishing splanchnic nerve and chromaffin cell stimulation in mouse adrenal slices with fast-scan cyclic voltammetry. American Journal of Physiology-Cell Physiology. 300 (1), C49-57 (2011).","journal-title":"American Journal of Physiology-Cell Physiology"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1113\/jphysiol.2001.012839","type":"journal-article","article-title":"Stimulation of recombinant Ca(v)3.2, T-type, Ca(2+) channel currents by CaMKIIgamma(C)","volume":"538","author":"Wolfe","year":"2002","unstructured":"Wolfe, J. T., Wang, H., Perez-Reyes, E., Barrett, P. Q. Stimulation of recombinant Ca(v)3.2, T-type, Ca(2+) channel currents by CaMKIIgamma(C). The Journal of Physiology. 538 (Pt 2), 343-355 (2002).","journal-title":"The Journal of Physiology"},{"issue":"5","key":"ref19","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1152\/ajpheart.00574.2019","type":"journal-article","article-title":"Fast in vivo detection of myocardial norepinephrine levels in the beating porcine heart","volume":"318","author":"Chan","year":"2020","unstructured":"Chan, S. A. et al. Fast in vivo detection of myocardial norepinephrine levels in the beating porcine heart. American Journal of Physiology-Heart and Circulatory Physiology. 318 (5), H1091-H1099 (2020).","journal-title":"American Journal of Physiology-Heart and Circulatory Physiology"},{"key":"ref20","type":"book","volume-title":"Single-Channel Recording, Second Edition","author":"Chow","year":"1995","unstructured":"Chow, R. H., von R\u00fcden, L. in Single-Channel Recording, Second Edition. (eds. B. Sakmann & E. Neher). 245-275. Plenum Press (1995)."},{"key":"ref21","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1186\/1472-6750-11-63","type":"journal-article","article-title":"Facile, high efficiency immobilization of lipase enzyme on magnetic iron oxide nanoparticles via a biomimetic coating","volume":"11","author":"Ren","year":"2011","unstructured":"Ren, Y. et al. Facile, high efficiency immobilization of lipase enzyme on magnetic iron oxide nanoparticles via a biomimetic coating. BMC Biotechnology. 11, 63 (2011).","journal-title":"BMC Biotechnology"}],"container-title":["Journal of Visualized Experiments"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jove.com\/t\/63926\/time-resolved-vivo-measurement-neuropeptide-dynamics-capacitive","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T19:53:34Z","timestamp":1792612414000},"score":1,"resource":{"primary":{"URL":"https:\/\/app.jove.com\/t\/63926"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,19]]},"references-count":21,"journal-issue":{"issue":"183","published-online":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.3791\/63926","relation":{},"ISSN":["1940-087X"],"issn-type":[{"value":"1940-087X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,19]]}}}