{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T18:41:12Z","timestamp":1792608072752,"version":"4.5.0"},"reference-count":18,"publisher":"MyJove Corporation","issue":"195","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JoVE"],"DOI":"10.3791\/65147","type":"journal-article","created":{"date-parts":[[2023,5,14]],"date-time":"2023-05-14T20:00:29Z","timestamp":1684094429000},"source":"Crossref","is-referenced-by-count":1,"title":["Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen"],"prefix":"10.3791","author":[{"given":"Tyler P.","family":"Graf","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kadryn","family":"Kadasia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Melhorn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliza","family":"Kessler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haisong","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsvetelina","family":"Baryakova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samantha","family":"Brady","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin J.","family":"McHugh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2098","published-online":{"date-parts":[[2023,5,12]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/S0140-6736(20)32657-X","type":"journal-article","article-title":"Estimating the health impact of vaccination against ten pathogens in 98 low-income and middle-income countries from 2000 to 2030: a modelling study","volume":"397","author":"Li","year":"2021","unstructured":"Li, X. et al. Estimating the health impact of vaccination against ten pathogens in 98 low-income and middle-income countries from 2000 to 2030: a modelling study. The Lancet. 397 (10272), 398-408 (2021).","journal-title":"The Lancet"},{"issue":"666","key":"ref2","doi-asserted-by":"crossref","first-page":"eabm1732","DOI":"10.1126\/scitranslmed.abm1732","type":"journal-article","article-title":"Translating diagnostics and drug delivery technologies to low-resource settings","volume":"14","author":"Euliano","year":"2022","unstructured":"Euliano, E. M., Sklavounos, A. A., Wheeler, A. R., McHugh, K. J. Translating diagnostics and drug delivery technologies to low-resource settings. Science Translational Medicine. 14 (666), eabm1732 (2022).","journal-title":"Science Translational Medicine"},{"issue":"5","key":"ref3","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1503\/cmaj.071709","type":"journal-article","article-title":"Rabies: old disease, new challenges","volume":"178","author":"Haider","year":"2008","unstructured":"Haider, S. Rabies: old disease, new challenges. Canadian Medical Association Journal. 178 (5), 562-563 (2008).","journal-title":"Canadian Medical Association Journal"},{"issue":"4","key":"ref4","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1038\/nrmicro.2018.11","type":"journal-article","article-title":"The spread and evolution of rabies virus: conquering new frontiers","volume":"16","author":"Fisher","year":"2018","unstructured":"Fisher, C. R., Streicker, D. G., Schnell, M. J. The spread and evolution of rabies virus: conquering new frontiers. Nature Reviews Microbiology. 16 (4), 241-255 (2018).","journal-title":"Nature Reviews Microbiology"},{"key":"ref5","type":"book","volume-title":"Rabies and Rabies Vaccines","author":"Nagarajan","year":"2020","unstructured":"Nagarajan, T., Rupprecht, C. E. Rabies and Rabies Vaccines. Springer International Publishing. (2020)."},{"issue":"4","key":"ref6","doi-asserted-by":"crossref","first-page":"918","DOI":"10.5811\/westjem.2020.3.45893","type":"journal-article","article-title":"Rabies vaccination compliance and reasons for incompletion","volume":"21","author":"Shi","year":"2020","unstructured":"Shi, T., Dunham, E. F., Nyland, J. E. Rabies vaccination compliance and reasons for incompletion. The Western Journal of Emergency Medicine. 21 (4), 918-923 (2020).","journal-title":"The Western Journal of Emergency Medicine"},{"issue":"1","key":"ref7","doi-asserted-by":"crossref","first-page":"58","DOI":"10.4103\/0019-557X.152867","type":"journal-article","article-title":"Compliance to anti-rabies vaccination in post-exposure prophylaxis","volume":"59","author":"Shankaraiah","year":"2015","unstructured":"Shankaraiah, R. H., Rajashekar, R. A., Veena, V., Hanumanthaiah, A, N, D. Compliance to anti-rabies vaccination in post-exposure prophylaxis. Indian Journal of Public Health. 59 (1), 58-60 (2015).","journal-title":"Indian Journal of Public Health"},{"issue":"1","key":"ref8","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0167-7799(98)01272-4","type":"journal-article","article-title":"Single-administration vaccines: controlled-release technology to mimic repeated immunizations","volume":"17","author":"Cleland","year":"1999","unstructured":"Cleland, J. L. Single-administration vaccines: controlled-release technology to mimic repeated immunizations. Trends in Biotechnology. 17 (1), 25-29 (1999).","journal-title":"Trends in Biotechnology"},{"issue":"3","key":"ref9","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/0168-3659(94)00123-C","type":"journal-article","article-title":"A novel emulsification-solvent extraction technique for production of protein loaded biodegradable microparticles for vaccine and drug delivery","volume":"33","author":"Yeh","year":"1995","unstructured":"Yeh, M. K., Coombes, A. G. A., Jenkins, P. G., Davis, S. S. A novel emulsification-solvent extraction technique for production of protein loaded biodegradable microparticles for vaccine and drug delivery. Journal of Controlled Release. 33 (3), 437-445 (1995).","journal-title":"Journal of Controlled Release"},{"issue":"5","key":"ref10","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1002\/jps.10361","type":"journal-article","article-title":"An experimental divalent vaccine based on biodegradable microspheres induces protective immunity against tetanus and diphtheria","volume":"92","author":"Peyre","year":"2003","unstructured":"Peyre, M., Sesardic, D., Merkle, H. P., Gander, B., Johansen, P. An experimental divalent vaccine based on biodegradable microspheres induces protective immunity against tetanus and diphtheria. Journal of Pharmaceutical Sciences. 92 (5), 957-966 (2003).","journal-title":"Journal of Pharmaceutical Sciences"},{"issue":"10","key":"ref11","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1023\/A:1026498209874","type":"journal-article","article-title":"Protein instability in poly(lactic-co-glycolic acid) microparticles","volume":"17","author":"Mvan de Weert","year":"2000","unstructured":"van de Weert, M., Hennink, W. E., Jiskoot, W. Protein instability in poly(lactic-co-glycolic acid) microparticles. Pharmaceutical Research. 17 (10), 1159-1167 (2000).","journal-title":"Pharmaceutical Research"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"e2300228","DOI":"10.1002\/adma.202300228","type":"journal-article","article-title":"A scalable platform for fabricating biodegradable microparticles with pulsatile drug release","author":"Graf","year":"2023","unstructured":"Graf, T. P. A scalable platform for fabricating biodegradable microparticles with pulsatile drug release. Advanced Materials. e2300228 (2023).","journal-title":"Advanced Materials"},{"issue":"4","key":"ref13","first-page":"92","type":"journal-article","article-title":"FDA's poly (lactic-co-glycolic acid) research program and regulatory outcomes","volume":"23","author":"Wang","year":"2021","unstructured":"Wang, Y., Qin, B., Xia, G., Choi, S. H. FDA's poly (lactic-co-glycolic acid) research program and regulatory outcomes. The American Association of Pharmaceutical Scientists Journal. 23 (4), 92 (2021).","journal-title":"The American Association of Pharmaceutical Scientists Journal"},{"issue":"6","key":"ref14","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1016\/j.xphs.2018.01.027","type":"journal-article","article-title":"Development of stabilizing formulations of a trivalent inactivated poliovirus vaccine in a dried state for delivery in the NanopatchTM microprojection array","volume":"107","author":"Wan","year":"2018","unstructured":"Wan, Y. et al. Development of stabilizing formulations of a trivalent inactivated poliovirus vaccine in a dried state for delivery in the NanopatchTM microprojection array. Journal of Pharmaceutical Sciences. 107 (6), 1540-1551 (2018).","journal-title":"Journal of Pharmaceutical Sciences"},{"issue":"19","key":"ref15","doi-asserted-by":"crossref","first-page":"2203","DOI":"10.1016\/j.vaccine.2015.03.025","type":"journal-article","article-title":"Rabies vaccine preserved by vaporization is thermostable and immunogenic","volume":"33","author":"Smith","year":"2015","unstructured":"Smith, T. G., Siirin, M., Wu, X., Hanlon, C. A., Bronshtein, V. Rabies vaccine preserved by vaporization is thermostable and immunogenic. Vaccine. 33 (19), 2203-2206 (2015).","journal-title":"Vaccine"},{"issue":"6356","key":"ref16","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1126\/science.aaf7447","type":"journal-article","article-title":"Fabrication of fillable microparticles and other complex 3D microstructures","volume":"357","author":"McHugh","year":"2017","unstructured":"McHugh, K. J. et al. Fabrication of fillable microparticles and other complex 3D microstructures. Science. 357 (6356), 1138-1142 (2017).","journal-title":"Science"},{"issue":"1","key":"ref17","doi-asserted-by":"crossref","first-page":"8149","DOI":"10.1038\/s41598-020-64572-6","type":"journal-article","article-title":"Rabies vaccine characterization by nanoparticle tracking analysis","volume":"10","author":"Sanchez","year":"2020","unstructured":"Sanchez, M. E. N. et al. Rabies vaccine characterization by nanoparticle tracking analysis. Scientific Reports. 10 (1), 8149 (2020).","journal-title":"Scientific Reports"},{"issue":"1","key":"ref18","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1023\/A:1007582911958","type":"journal-article","article-title":"Visual evidence of acidic environment within degrading poly(lactic-co-glycolic acid) (PLGA) microspheres","volume":"17","author":"Fu","year":"2000","unstructured":"Fu, K., Pack, D. W., Klibanov, A. M., Langer, R. Visual evidence of acidic environment within degrading poly(lactic-co-glycolic acid) (PLGA) microspheres. Pharmaceutical Research. 17 (1), 100-106 (2000).","journal-title":"Pharmaceutical Research"}],"container-title":["Journal of Visualized Experiments"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jove.com\/t\/65147\/fabrication-pulsatile-polymeric-microparticles-encapsulating-rabies","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T18:14:22Z","timestamp":1792606462000},"score":1,"resource":{"primary":{"URL":"https:\/\/app.jove.com\/t\/65147"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,12]]},"references-count":18,"journal-issue":{"issue":"195","published-online":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.3791\/65147","relation":{},"ISSN":["1940-087X"],"issn-type":[{"value":"1940-087X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,12]]}}}