{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T16:41:16Z","timestamp":1792600876640,"version":"4.5.0"},"reference-count":41,"publisher":"MyJove Corporation","issue":"212","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JoVE"],"DOI":"10.3791\/66504","type":"journal-article","created":{"date-parts":[[2024,10,25]],"date-time":"2024-10-25T20:00:22Z","timestamp":1729886422000},"source":"Crossref","is-referenced-by-count":0,"title":["Z-Scores for Assessing Ovarian Reserve in Young Patients Undergoing Fertility Preservation"],"prefix":"10.3791","author":[{"given":"Jasmin","family":"Hassan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pauliina","family":"Damdimopoulou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atte","family":"Lahtinen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirsi","family":"Jahnukainen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katri","family":"Knuus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ganesh","family":"Acharya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richelle D.","family":"Bj\u00f6rvang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2098","published-online":{"date-parts":[[2024,10,25]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/bs.vh.2018.01.009","type":"journal-article","article-title":"The ovarian cycle","volume":"107","author":"Richards","year":"2018","unstructured":"Richards, J. A. S. The ovarian cycle. Vitam Horm. 107, 1-25 (2018).","journal-title":"Vitam Horm"},{"issue":"1","key":"ref2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0008772","type":"journal-article","article-title":"Human ovarian reserve from conception to the menopause","volume":"5","author":"Wallace","year":"2010","unstructured":"Wallace, W. H. B., Kelsey, T. W. Human ovarian reserve from conception to the menopause. PLoS One. 5 (1), 1-9 (2010).","journal-title":"PLoS One"},{"issue":"4","key":"ref3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1095\/biolreprod.113.117077","type":"journal-article","article-title":"The ovarian reserve of primordial follicles and the dynamic reserve of antral growing follicles: What is the link","volume":"90","author":"Monniaux","year":"2014","unstructured":"Monniaux, D. et al. The ovarian reserve of primordial follicles and the dynamic reserve of antral growing follicles: What is the link? Biol Reprod. 90 (4), 1-11 (2014).","journal-title":"Biol Reprod"},{"key":"ref4","type":"book","volume-title":"The early stages of follicular growth in biology and pathology of the oocyte","author":"Gougeon","year":"2013","unstructured":"Gougeon, A. The early stages of follicular growth in biology and pathology of the oocyte. (eds. Trounson, A., Gosden, R., Eichenlaub-Ritter, U.), 50-61 Cambridge University Press, (2013)."},{"issue":"3","key":"ref5","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.ando.2010.02.021","type":"journal-article","article-title":"Human ovarian follicular development: From activation of resting follicles to preovulatory maturation","volume":"71","author":"Gougeon","year":"2010","unstructured":"Gougeon, A. Human ovarian follicular development: From activation of resting follicles to preovulatory maturation. Ann Endocrinol. 71 (3), 132-143 (2010).","journal-title":"Ann Endocrinol"},{"issue":"2","key":"ref6","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1097\/gme.0b013e31823b0b2e","type":"journal-article","article-title":"Ovarian primordial and non-growing follicle counts according to the stages of reproductive aging workshop (STRAW) staging system","volume":"19","author":"Hansen","year":"2012","unstructured":"Hansen, K. R., Craig, L. B., Zavy, M. T., Klein, N. A., Soules, M. R. Ovarian primordial and non-growing follicle counts according to the stages of reproductive aging workshop (STRAW) staging system. Menopause. 19 (2), 164-171 (2012).","journal-title":"Menopause"},{"issue":"3","key":"ref7","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.ogc.2011.05.002","type":"journal-article","article-title":"The timing of the age at which natural menopause occurs","volume":"38","author":"Gold","year":"2011","unstructured":"Gold, E. B. The timing of the age at which natural menopause occurs. Obstet Gynecol Clin North Am. 38 (3), 425-440 (2011).","journal-title":"Obstet Gynecol Clin North Am"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1093\/stmcls\/sxac015","type":"journal-article","article-title":"Workflow optimization for identification of female germline or oogonial stem cells in human ovarian cortex using single-cell RNA sequence analysis","volume":"40","author":"Alberico","year":"2022","unstructured":"Alberico, H. et al. Workflow optimization for identification of female germline or oogonial stem cells in human ovarian cortex using single-cell RNA sequence analysis. Stem Cells. 40, 523-536 (2022).","journal-title":"Stem Cells"},{"issue":"3","key":"ref9","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1038\/nm.2669","type":"journal-article","article-title":"Oocyte formation by mitotically active germ cells purified from ovaries of reproductive-age women","volume":"18","author":"White","year":"2012","unstructured":"White, Y. A. R. et al. Oocyte formation by mitotically active germ cells purified from ovaries of reproductive-age women. Nat Med. 18 (3), 413-422 (2012).","journal-title":"Nat Med"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1038\/s41467-020-14936-3","type":"journal-article","article-title":"Single-cell analysis of human ovarian cortex identifies distinct cell populations but no oogonial stem cells","volume":"11","author":"Wagner","year":"2020","unstructured":"Wagner, M. et al. Single-cell analysis of human ovarian cortex identifies distinct cell populations but no oogonial stem cells. Nat Commun. 11, 1147 (2020).","journal-title":"Nat Commun"},{"issue":"2","key":"ref11","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1093\/stmcls\/sxac084","type":"journal-article","article-title":"In reply: Revisiting claims of the continued absence of functional germline stem cells in adult ovaries","volume":"41","author":"Yoshihara","year":"2023","unstructured":"Yoshihara, M. et al. In reply: Revisiting claims of the continued absence of functional germline stem cells in adult ovaries. Stem Cells. 41 (2), 205-206 (2023).","journal-title":"Stem Cells"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1093\/stmcls\/sxac070","type":"journal-article","article-title":"The continued absence of functional germline stem cells in adult ovaries","volume":"41","author":"Yoshihara","year":"2023","unstructured":"Yoshihara, M. et al. The continued absence of functional germline stem cells in adult ovaries. Stem Cells. 41, 105-110 (2023).","journal-title":"Stem Cells"},{"issue":"5","key":"ref13","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1093\/humupd\/5.5.483","type":"journal-article","article-title":"Premature ovarian failure: A systematic review on therapeutic interventions to restore ovarian function and achieve pregnancy","volume":"5","author":"Van Kasteren","year":"1999","unstructured":"Van Kasteren, Y. M., Schoemaker, J. Premature ovarian failure: A systematic review on therapeutic interventions to restore ovarian function and achieve pregnancy. Hum Reprod Update. 5 (5), 483-492 (1999).","journal-title":"Hum Reprod Update"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.bpobgyn.2021.09.011","type":"journal-article","article-title":"Premature ovarian insufficiency","volume":"81","author":"McGlacken-Byrne","year":"2022","unstructured":"McGlacken-Byrne, S. M., Conway, G. S. Premature ovarian insufficiency. Best Pract Res Clin Obstet Gynaecol. 81, 98-110 (2022).","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"issue":"4","key":"ref15","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.ando.2022.06.001","type":"journal-article","article-title":"Turner syndrome and fertility","volume":"83","author":"Viuff","year":"2022","unstructured":"Viuff, M., Gravholt, C. H. Turner syndrome and fertility. Ann Endocrinol. 83 (4), 244-249 (2022).","journal-title":"Ann Endocrinol"},{"issue":"5","key":"ref16","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1111\/aogs.13616","type":"journal-article","article-title":"Ovarian tissue cryopreservation for fertility preservation in 418 girls and adolescents up to 15 years of age facing highly gonadotoxic treatment: Twenty years of experience at a single center","volume":"98","author":"Poirot","year":"2019","unstructured":"Poirot, C. et al. Ovarian tissue cryopreservation for fertility preservation in 418 girls and adolescents up to 15 years of age facing highly gonadotoxic treatment: Twenty years of experience at a single center. Acta Obstet Gynecol Scand. 98 (5), 630-637 (2019).","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"1","key":"ref17","first-page":"154","type":"journal-article","article-title":"Cryopreservation of ovarian tissue for fertility preservation in a large cohort of young girls: Focus on pubertal development","volume":"32","author":"Jensen","year":"2017","unstructured":"Jensen, A. K. et al. Cryopreservation of ovarian tissue for fertility preservation in a large cohort of young girls: Focus on pubertal development. Hum Reprod. 32 (1), 154-164 (2017).","journal-title":"Hum Reprod"},{"issue":"6","key":"ref18","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1016\/j.fertnstert.2019.09.013","type":"journal-article","article-title":"Fertility preservation in patients undergoing gonadotoxic therapy or gonadectomy: A committee opinion","volume":"112","year":"2019","unstructured":"The Practice Committee of the American Society for Reproductive Medicine. Fertility preservation in patients undergoing gonadotoxic therapy or gonadectomy: A committee opinion. Fertil Steril. 112 (6), 1022-1033 (2019).","journal-title":"Fertil Steril"},{"key":"ref19","volume-title":"ART Fact Sheet","year":"2020","unstructured":"European Society of Human Reproduction and Embryology. ART Fact Sheet. https:\/\/www.eshre.eu\/Press-Room\/Resources (2020)."},{"key":"ref20","doi-asserted-by":"crossref","first-page":"1151254","DOI":"10.3389\/fvets.2023.1151254","type":"journal-article","article-title":"A comprehensive review and update on human fertility cryopreservation methods and tools","volume":"10","author":"Antonouli","year":"2023","unstructured":"Antonouli, S. et al. A comprehensive review and update on human fertility cryopreservation methods and tools. Front Vet Sci. 10, 1151254 (2023).","journal-title":"Front Vet Sci"},{"key":"ref21","volume-title":"Nordic Society of Pediatric Hematology and Oncology (NOPHO)","year":"2013","unstructured":"Nordic Society of Pediatric Hematology and Oncology (NOPHO). http:\/\/www.nopho.net (2013)."},{"issue":"2","key":"ref22","doi-asserted-by":"crossref","first-page":"102290","DOI":"10.1016\/j.jogoh.2021.102290","type":"journal-article","article-title":"Review of ovarian tissue cryopreservation techniques for fertility preservation","volume":"51","author":"Bahroudi","year":"2022","unstructured":"Bahroudi, Z. et al. Review of ovarian tissue cryopreservation techniques for fertility preservation. J Gynecol Obstet Hum Reprod. 51 (2), 102290 (2022).","journal-title":"J Gynecol Obstet Hum Reprod"},{"issue":"3","key":"ref23","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1007\/s10815-016-0843-9","type":"journal-article","article-title":"86 successful births and 9 ongoing pregnancies worldwide in women transplanted with frozen-thawed ovarian tissue: Focus on birth and perinatal outcome in 40 of these children","volume":"34","author":"Jensen","year":"2017","unstructured":"Jensen, A. K. et al. 86 successful births and 9 ongoing pregnancies worldwide in women transplanted with frozen-thawed ovarian tissue: Focus on birth and perinatal outcome in 40 of these children. J Assist Reprod Genet. 34 (3), 325-336 (2017).","journal-title":"J Assist Reprod Genet"},{"issue":"17","key":"ref24","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1056\/NEJMra1614676","type":"journal-article","article-title":"Fertility preservation in women","volume":"377","author":"Donnez","year":"2017","unstructured":"Donnez, J., Dolmans, M.-M. Fertility preservation in women. N Engl J Med. 377 (17), 1657-1665 (2017).","journal-title":"N Engl J Med"},{"issue":"2","key":"ref25","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.fertnstert.2020.04.050","type":"journal-article","article-title":"Importance of patient selection to analyze in vitro fertilization outcome with transplanted cryopreserved ovarian tissue","volume":"114","author":"Dolmans","year":"2020","unstructured":"Dolmans, M. M., Falcone, T., Patrizio, P. Importance of patient selection to analyze in vitro fertilization outcome with transplanted cryopreserved ovarian tissue. Fertil Steril. 114 (2), 279-280 (2020).","journal-title":"Fertil Steril"},{"issue":"9","key":"ref26","doi-asserted-by":"crossref","first-page":"2107","DOI":"10.1093\/humrep\/dev128","type":"journal-article","article-title":"Live birth after autograft of ovarian tissue cryopreserved during childhood","volume":"30","author":"Demeestere","year":"2015","unstructured":"Demeestere, I. et al. Live birth after autograft of ovarian tissue cryopreserved during childhood. Hum Reprod. 30 (9), 2107-2109 (2015).","journal-title":"Hum Reprod"},{"issue":"4","key":"ref27","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1016\/j.ejca.2012.09.028","type":"journal-article","article-title":"Case report: Stimulation of puberty in a girl with chemo- and radiation therapy-induced ovarian failure by transplantation of a small part of her frozen\/thawed ovarian tissue","volume":"49","author":"Ernst","year":"2013","unstructured":"Ernst, E., Kj\u00e6rsgaard, M., Birkeb\u00e6k, N. H., Clausen, N., Andersen, C. Y. Case report: Stimulation of puberty in a girl with chemo- and radiation therapy-induced ovarian failure by transplantation of a small part of her frozen\/thawed ovarian tissue. Eur J Cancer. 49 (4), 911-914 (2013).","journal-title":"Eur J Cancer"},{"issue":"10","key":"ref28","doi-asserted-by":"crossref","first-page":"2783","DOI":"10.3324\/haematol.2021.278828","type":"journal-article","article-title":"Successful pregnancies after transplantation of ovarian tissue retrieved and cryopreserved at time of childhood acute lymphoblastic leukemia - a case report","volume":"106","author":"Rodriguez-Wallberg","year":"2021","unstructured":"Rodriguez-Wallberg, K. A. et al. Successful pregnancies after transplantation of ovarian tissue retrieved and cryopreserved at time of childhood acute lymphoblastic leukemia - a case report. Haematologica. 106 (10), 2783-2787 (2021).","journal-title":"Haematologica"},{"issue":"4","key":"ref29","first-page":"432","type":"journal-article","article-title":"Successful pregnancy in a woman previously suffering from \u03b2-thalassemia following transplantation of ovarian tissue cryopreserved before puberty","volume":"70","author":"Matthews","year":"2018","unstructured":"Matthews, S. J., Picton, H., Ernst, E., Andersen, C. Y. Successful pregnancy in a woman previously suffering from \u03b2-thalassemia following transplantation of ovarian tissue cryopreserved before puberty. Minerva Ginecol. 70 (4), 432-435 (2018).","journal-title":"Minerva Ginecol"},{"issue":"4","key":"ref30","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1016\/j.fertnstert.2021.05.096","type":"journal-article","article-title":"Use of cryopreserved ovarian tissue in the Danish fertility preservation cohort","volume":"116","author":"Kristensen","year":"2021","unstructured":"Kristensen, S. G. et al. Use of cryopreserved ovarian tissue in the Danish fertility preservation cohort. Fertil Steril. 116 (4), 1098-1106 (2021).","journal-title":"Fertil Steril"},{"issue":"4","key":"ref31","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1017\/S0967199417000338","type":"journal-article","article-title":"Expectations and limitations of ovarian tissue transplantation","volume":"25","author":"Donfack","year":"2017","unstructured":"Donfack, N. J. et al. Expectations and limitations of ovarian tissue transplantation. Zygote. 25 (4), 391-403 (2017).","journal-title":"Zygote"},{"issue":"6","key":"ref32","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1093\/humrep\/deg246","type":"journal-article","article-title":"Density and distribution of primordial follicles in single pieces of cortex from 21 patients and in individual pieces of cortex from three entire human ovaries","volume":"18","author":"Schmidt","year":"2003","unstructured":"Schmidt, K. L. T., Byskov, A. G., Andersen, A. N., M\u00fcller, J., Andersen, C. Y. Density and distribution of primordial follicles in single pieces of cortex from 21 patients and in individual pieces of cortex from three entire human ovaries. Hum Reprod. 18 (6), 1158-1164 (2003).","journal-title":"Hum Reprod"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"103287","DOI":"10.1016\/j.rbmo.2023.103287","type":"journal-article","article-title":"Reference standards for follicular density in ovarian cortex from birth to sexual maturity","volume":"47","author":"Hassan","year":"2023","unstructured":"Hassan, J. et al. Reference standards for follicular density in ovarian cortex from birth to sexual maturity. Reprod Biomed Online. 47, 103287 (2023).","journal-title":"Reprod Biomed Online"},{"issue":"2","key":"ref34","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.rbmo.2020.11.001","type":"journal-article","article-title":"Ovarian tissue transportation: A systematic review","volume":"42","author":"Vilela","year":"2021","unstructured":"Vilela, J. de M. V., Dolmans, M. M., Amorim, C. A. Ovarian tissue transportation: A systematic review. Reprod Biomed Online. 42 (2), 351-365 (2021).","journal-title":"Reprod Biomed Online"},{"key":"ref35","type":"book","volume-title":"Anatomy, abdomen and pelvis, ovary","author":"Gibson","year":"2023","unstructured":"Gibson, E., Mahdy, H. Anatomy, abdomen and pelvis, ovary. StatPearls Publishing. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK545187\/ (2023)."},{"issue":"141","key":"ref36","first-page":"e58569","type":"journal-article","article-title":"Establishment and analysis of tumor slice explants as a prerequisite for diagnostic testing","author":"Nagaraj","year":"2018","unstructured":"Nagaraj, A. S. et al. Establishment and analysis of tumor slice explants as a prerequisite for diagnostic testing. J Vis Exp. 141, e58569 (2018).","journal-title":"J Vis Exp"},{"issue":"7","key":"ref37","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1093\/humrep\/deab075","type":"journal-article","article-title":"Improved preservation of ovarian tissue morphology that is compatible with antigen detection using a fixative mixture of formalin and acetic acid","volume":"36","author":"Adeniran","year":"2021","unstructured":"Adeniran, B. V., Bjarkadottir, B. D., Appeltant, R., Lane, S., Williams, S. A. Improved preservation of ovarian tissue morphology that is compatible with antigen detection using a fixative mixture of formalin and acetic acid. Hum Reprod. 36 (7), 1871-1890 (2021).","journal-title":"Hum Reprod"},{"issue":"1","key":"ref38","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-017-17204-5","type":"journal-article","article-title":"QuPath: Open-source software for digital pathology image analysis","volume":"7","author":"Bankhead","year":"2017","unstructured":"Bankhead, P. et al. QuPath: Open-source software for digital pathology image analysis. Sci Rep. 7 (1), 1-7 (2017).","journal-title":"Sci Rep"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"106589","DOI":"10.1016\/j.envint.2021.106589","type":"journal-article","article-title":"Persistent organic pollutants and the size of ovarian reserve in reproductive-aged women","volume":"155","author":"Bj\u00f6rvang","year":"2021","unstructured":"Bj\u00f6rvang, R. D. et al. Persistent organic pollutants and the size of ovarian reserve in reproductive-aged women. Environ Int. 155, 106589 (2021).","journal-title":"Environ Int"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.rbmo.2012.01.020","type":"journal-article","article-title":"Ovarian biopsy has no role as a routine diagnostic test of ovarian reserve: A systematic review","volume":"24","author":"Kwok","year":"2012","unstructured":"Kwok, R., Johnson, N. P. Ovarian biopsy has no role as a routine diagnostic test of ovarian reserve: A systematic review. Reprod Biomed Online. 24, 492-495 (2012).","journal-title":"Reprod Biomed Online"},{"issue":"1","key":"ref41","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-021-94915-w","type":"journal-article","article-title":"High-throughput spatial sensitive, quantitative phase microscopy using low spatial and high temporal coherent illumination","volume":"11","author":"Ahmad","year":"2021","unstructured":"Ahmad, A. et al. High-throughput spatial sensitive, quantitative phase microscopy using low spatial and high temporal coherent illumination. Sci Rep. 11 (1), 1-13 (2021).","journal-title":"Sci Rep"}],"container-title":["Journal of Visualized Experiments"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/app.jove.com\/t\/66504\/z-scores-for-assessing-ovarian-reserve-young-patients-undergoing","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T15:57:47Z","timestamp":1792598267000},"score":1,"resource":{"primary":{"URL":"https:\/\/app.jove.com\/t\/66504\/z-scores-for-assessing-ovarian-reserve-young-patients-undergoing"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,25]]},"references-count":41,"journal-issue":{"issue":"212","published-online":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.3791\/66504","relation":{},"ISSN":["1940-087X"],"issn-type":[{"value":"1940-087X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,25]]}}}