{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T13:39:31Z","timestamp":1792589971945,"version":"4.5.0"},"reference-count":12,"publisher":"MyJove Corporation","issue":"231","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JoVE"],"DOI":"10.3791\/70379","type":"journal-article","created":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T23:02:09Z","timestamp":1779058929000},"source":"Crossref","is-referenced-by-count":0,"title":["A Surgical Method to Establish a Murine Model of Knee Osteoarthritis using a Modified Hulth Procedure"],"prefix":"10.3791","author":[{"given":"Shaokang","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minjie","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunxiao","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kwensy","family":"Djoyce Ondo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinman","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2098","published-online":{"date-parts":[[2026,5,15]]},"reference":[{"issue":"1","key":"ref1","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1056\/NEJMcp1903768","type":"journal-article","article-title":"Osteoarthritis of the Knee","volume":"384","author":"Sharma","year":"2021","unstructured":"Sharma, L. Osteoarthritis of the Knee. N Engl J Med. 384 (1), 51-59 (2021).","journal-title":"N Engl J Med"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"16044","DOI":"10.1038\/boneres.2016.44","type":"journal-article","article-title":"Osteoarthritis: toward a comprehensive understanding of pathological mechanism","volume":"5","author":"Chen","year":"2017","unstructured":"Chen, D. et al. Osteoarthritis: toward a comprehensive understanding of pathological mechanism. Bone Res. 5, 16044 (2017).","journal-title":"Bone Res"},{"issue":"9","key":"ref3","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/j.joca.2007.03.006","type":"journal-article","article-title":"The surgical destabilization of the medial meniscus (DMM) model of osteoarthritis in the 129\/SvEv mouse","volume":"15","author":"Glasson","year":"2007","unstructured":"Glasson, S. S., Blanchet, T. J., Morris, E. A. The surgical destabilization of the medial meniscus (DMM) model of osteoarthritis in the 129\/SvEv mouse. Osteoarthritis Cartilage. 15 (9), 1061-1069 (2007).","journal-title":"Osteoarthritis Cartilage"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.jare.2025.01.010","type":"journal-article","article-title":"Antioxidant taurine inhibits chondrocyte ferroptosis through upregulation of OGT\/Gpx4 signaling in osteoarthritis induced by anterior cruciate ligament transection","volume":"77","author":"Zhou","year":"2025","unstructured":"Zhou, X. et al. Antioxidant taurine inhibits chondrocyte ferroptosis through upregulation of OGT\/Gpx4 signaling in osteoarthritis induced by anterior cruciate ligament transection. J Adv Res. 77, 551-567 (2025).","journal-title":"J Adv Res"},{"issue":"8","key":"ref5","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1053\/joca.2001.0472","type":"journal-article","article-title":"Moderation of iodoacetate-induced experimental osteoarthritis in rats by matrix metalloproteinase inhibitors","volume":"9","author":"Jal Janusz","year":"2001","unstructured":"Janusz, M. J. et al. Moderation of iodoacetate-induced experimental osteoarthritis in rats by matrix metalloproteinase inhibitors. Osteoarthritis Cartilage. 9 (8), 751-760 (2001).","journal-title":"Osteoarthritis Cartilage"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.jot.2020.07.005","type":"journal-article","article-title":"An impaired healing model of osteochondral defect in papain-induced arthritis","volume":"26","author":"Meng","year":"2021","unstructured":"Meng, X. et al. An impaired healing model of osteochondral defect in papain-induced arthritis. J Orthop Translat. 26, 101-110 (2021).","journal-title":"J Orthop Translat"},{"issue":"6","key":"ref7","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1053\/joca.1999.0258","type":"journal-article","article-title":"Articular collagen degradation in the Hulth-Telhag model of osteoarthritis","volume":"7","author":"Rogart","year":"1999","unstructured":"Rogart, J. N., Barrach, H. J., Chichester, C. O. Articular collagen degradation in the Hulth-Telhag model of osteoarthritis. Osteoarthritis Cartilage. 7 (6), 539-547 (1999).","journal-title":"Osteoarthritis Cartilage"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"17012","DOI":"10.1038\/boneres.2017.12","type":"journal-article","article-title":"Utilization of longitudinal ultrasound to quantify joint soft-tissue changes in a mouse model of posttraumatic osteoarthritis","volume":"5","author":"Xu","year":"2017","unstructured":"Xu, H. et al. Utilization of longitudinal ultrasound to quantify joint soft-tissue changes in a mouse model of posttraumatic osteoarthritis. Bone Res. 5, 17012 (2017).","journal-title":"Bone Res"},{"issue":"Suppl 3","key":"ref9","doi-asserted-by":"crossref","first-page":"S17","DOI":"10.1016\/j.joca.2010.05.025","type":"journal-article","article-title":"The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the mouse","volume":"18","author":"Glasson","year":"2010","unstructured":"Glasson, S. S., Chambers, M. G., Van Den Berg, W. B., Little, C. B. The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the mouse. Osteoarthritis Cartilage. 18 Suppl 3, S17-S23 (2010).","journal-title":"Osteoarthritis Cartilage"},{"issue":"19","key":"ref10","doi-asserted-by":"crossref","first-page":"11342","DOI":"10.3390\/ijms231911342","type":"journal-article","article-title":"Motor behavioral deficits in the Cuprizone model: Validity of the rotarod test paradigm","volume":"23","author":"Lubrich","year":"2022","unstructured":"Lubrich, C., Giesler, P., Kipp, M. Motor behavioral deficits in the Cuprizone model: Validity of the rotarod test paradigm. Int J Mol Sci. 23 (19), 11342 (2022).","journal-title":"Int J Mol Sci"},{"issue":"2","key":"ref11","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.gene.2013.11.091","type":"journal-article","article-title":"Pain assessment in animal models of osteoarthritis","volume":"537","author":"Piel","year":"2014","unstructured":"Piel, M. J., Kroin, J. S., van Wijnen, A. J., Kc, R., Im, H. J. Pain assessment in animal models of osteoarthritis. Gene. 537 (2), 184-188 (2014).","journal-title":"Gene"},{"issue":"10","key":"ref12","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1016\/j.joca.2024.05.006","type":"journal-article","article-title":"A standardized approach to evaluation and reporting of synovial histopathology in two surgically induced murine models of osteoarthritis","volume":"32","author":"Obeidat","year":"2024","unstructured":"Obeidat, A. M. et al. A standardized approach to evaluation and reporting of synovial histopathology in two surgically induced murine models of osteoarthritis. Osteoarthritis Cartilage. 32 (10), 1273-1282 (2024).","journal-title":"Osteoarthritis Cartilage"}],"container-title":["Journal of Visualized Experiments"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jove.com\/t\/70379\/a-surgical-method-to-establish-murine-model-knee-osteoarthritis-using","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T12:48:31Z","timestamp":1792586911000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jove.com\/t\/70379\/a-surgical-method-to-establish-murine-model-knee-osteoarthritis-using"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,15]]},"references-count":12,"journal-issue":{"issue":"231","published-online":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.3791\/70379","relation":{},"ISSN":["1940-087X"],"issn-type":[{"value":"1940-087X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,15]]}}}