{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T06:12:35Z","timestamp":1779257555117,"version":"3.51.4"},"reference-count":30,"publisher":"XMLink","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP24ck0106918"],"award-info":[{"award-number":["JP24ck0106918"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ejgo.org"],"crossmark-restriction":false},"short-container-title":["J Gynecol Oncol"],"DOI":"10.3802\/jgo.2026.37.e126","type":"journal-article","created":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T05:49:13Z","timestamp":1779256153000},"update-policy":"https:\/\/doi.org\/10.3802\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hokkaido phase II study of photo-immunotherapy combination with ASP-1929 for recurrent or persistent EGFR-positive vulvar, vaginal, and cervical cancers not amenable to further radiotherapy (HICARi study)"],"prefix":"10.3802","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1033-3920","authenticated-orcid":false,"given":"Hiroshi","family":"Asano","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, Sapporo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8759-9607","authenticated-orcid":false,"given":"Hiroyuki","family":"Yamazaki","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, Sapporo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1496-214X","authenticated-orcid":false,"given":"Hiroko","family":"Matsumiya","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, Sapporo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6254-2225","authenticated-orcid":false,"given":"Isao","family":"Yokota","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Hokkaido University Graduate School of Medicine, Sapporo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6537-376X","authenticated-orcid":false,"given":"Kazufumi","family":"Okada","sequence":"additional","affiliation":[{"name":"Data Science Center, Promotion Unit, Institute of Health Science Innovation for Medical Care, Hokkaido University Hospital, Sapporo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-8408-3370","authenticated-orcid":false,"given":"Ryutaro","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, Sapporo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-9596-9661","authenticated-orcid":false,"given":"Kanako C.","family":"Hatanaka","sequence":"additional","affiliation":[{"name":"Center for Development of Advanced Diagnostics (C-DAD), Promotion Unit, Institute of Health Science Innovation for Medical Care, Hokkaido University Hospital, Sapporo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6972-3843","authenticated-orcid":false,"given":"Yuko","family":"Sasajima","sequence":"additional","affiliation":[{"name":"Department of Pathology, Teikyo University School of Medicine, Tokyo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6765-6117","authenticated-orcid":false,"given":"Michiko","family":"Nagamine","sequence":"additional","affiliation":[{"name":"Department of Pathology and Clinical Laboratories, National Cancer Center Hospital East, Kashiwa, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3128-1477","authenticated-orcid":false,"given":"Yutaka","family":"Hatanaka","sequence":"additional","affiliation":[{"name":"Center for Development of Advanced Diagnostics (C-DAD), Promotion Unit, Institute of Health Science Innovation for Medical Care, Hokkaido University Hospital, Sapporo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0782-6118","authenticated-orcid":false,"given":"Fumi","family":"Kato","sequence":"additional","affiliation":[{"name":"Department of Radiology, Jichi Medical University Saitama Medical Center, Saitama, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8855-7054","authenticated-orcid":false,"given":"Junko","family":"Takahama","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Nara Prefecture General Medical Center, Nara, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7243-1454","authenticated-orcid":false,"given":"Takahiro","family":"Tsuboyama","sequence":"additional","affiliation":[{"name":"Department of Radiology, Kobe University Graduate School of Medicine, Kobe, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7082-0803","authenticated-orcid":false,"given":"Yudai","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Promotion Unit, Clinical Research and Medical Innovation Center, Institute of Health Science Innovation for Medical Care, Hokkaido University Hospital, Sapporo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-8978-7139","authenticated-orcid":false,"given":"Naoko","family":"Okita","sequence":"additional","affiliation":[{"name":"Promotion Unit, Clinical Research and Medical Innovation Center, Institute of Health Science Innovation for Medical Care, Hokkaido University Hospital, Sapporo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4189-6187","authenticated-orcid":false,"given":"Hidemichi","family":"Watari","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, Sapporo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"18617","published-online":{"date-parts":[[2026]]},"reference":[{"key":"10.3802\/jgo.2026.37.e126_ref1","doi-asserted-by":"crossref","first-page":"2332","DOI":"10.1021\/acs.accounts.9b00273","volume":"52","author":"Kobayashi","year":"2019","journal-title":"Acc Chem Res"},{"key":"10.3802\/jgo.2026.37.e126_ref2","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1038\/nm.2554","volume":"17","author":"Mitsunaga","year":"2011","journal-title":"Nat Med"},{"key":"10.3802\/jgo.2026.37.e126_ref3","doi-asserted-by":"crossref","first-page":"1812","DOI":"10.1007\/s10147-021-01960-6","volume":"26","author":"Tahara","year":"2021","journal-title":"Int J Clin Oncol"},{"key":"10.3802\/jgo.2026.37.e126_ref4","doi-asserted-by":"crossref","first-page":"3875","DOI":"10.1002\/hed.26885","volume":"43","author":"Cognetti","year":"2021","journal-title":"Head Neck"},{"key":"10.3802\/jgo.2026.37.e126_ref5","first-page":"7","volume":"72","author":"Siegel","year":"2022","journal-title":"CA Cancer J Clin"},{"key":"10.3802\/jgo.2026.37.e126_ref6","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1006\/gyno.2001.6171","volume":"81","author":"Tjalma","year":"2001","journal-title":"Gynecol Oncol"},{"key":"10.3802\/jgo.2026.37.e126_ref7","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1136\/ijgc-00009577-200307000-00019","volume":"13","author":"Gaarenstroom","year":"2003","journal-title":"Int J Gynecol Cancer"},{"key":"10.3802\/jgo.2026.37.e126_ref8","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/s10147-017-1193-z","volume":"23","author":"Saito","year":"2018","journal-title":"Int J Clin Oncol"},{"key":"10.3802\/jgo.2026.37.e126_ref9","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1002\/ijgo.12749","volume":"145","author":"Bhatla","year":"2019","journal-title":"Int J Gynaecol Obstet"},{"key":"10.3802\/jgo.2026.37.e126_ref10","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1097\/IGC.0b013e318291e5ef","volume":"23","author":"Spoozak","year":"2013","journal-title":"Int J Gynecol Cancer"},{"key":"10.3802\/jgo.2026.37.e126_ref11","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1200\/GO.21.00025","volume":"7","author":"Krakauer","year":"2021","journal-title":"JCO Glob Oncol"},{"key":"10.3802\/jgo.2026.37.e126_ref12","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1097\/IGC.0b013e31824b4058","volume":"22","author":"Han","year":"2012","journal-title":"Int J Gynecol Cancer"},{"key":"10.3802\/jgo.2026.37.e126_ref13","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1093\/annonc\/mdp043","volume":"20","author":"Witteveen","year":"2009","journal-title":"Ann Oncol"},{"key":"10.3802\/jgo.2026.37.e126_ref14","doi-asserted-by":"crossref","first-page":"3667","DOI":"10.1038\/s41598-021-83317-7","volume":"11","author":"How","year":"2021","journal-title":"Sci Rep"},{"key":"10.3802\/jgo.2026.37.e126_ref15","doi-asserted-by":"crossref","first-page":"2825","DOI":"10.1200\/JCO.19.00739","volume":"37","author":"Naumann","year":"2019","journal-title":"J Clin Oncol"},{"key":"10.3802\/jgo.2026.37.e126_ref16","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.ygyno.2007.08.008","volume":"107","author":"du Bois","year":"2007","journal-title":"Gynecol Oncol"},{"key":"10.3802\/jgo.2026.37.e126_ref17","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1056\/NEJMoa1309748","volume":"370","author":"Tewari","year":"2014","journal-title":"N Engl J Med"},{"key":"10.3802\/jgo.2026.37.e126_ref18","doi-asserted-by":"crossref","first-page":"1654","DOI":"10.1016\/S0140-6736(17)31607-0","volume":"390","author":"Tewari","year":"2017","journal-title":"Lancet"},{"key":"10.3802\/jgo.2026.37.e126_ref19","doi-asserted-by":"crossref","first-page":"1856","DOI":"10.1056\/NEJMoa2112435","volume":"385","author":"Colombo","year":"2021","journal-title":"N Engl J Med"},{"key":"10.3802\/jgo.2026.37.e126_ref20","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1056\/NEJMoa2112187","volume":"386","author":"Tewari","year":"2022","journal-title":"N Engl J Med"},{"key":"10.3802\/jgo.2026.37.e126_ref21","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.ygyno.2012.06.028","volume":"127","author":"Horowitz","year":"2012","journal-title":"Gynecol Oncol"},{"key":"10.3802\/jgo.2026.37.e126_ref22","doi-asserted-by":"crossref","first-page":"7581","DOI":"10.1038\/s41467-022-35133-4","volume":"13","author":"Xia","year":"2022","journal-title":"Nat Commun"},{"key":"10.3802\/jgo.2026.37.e126_ref23","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0140-6736(18)32470-X","volume":"393","author":"Cohen","year":"2019","journal-title":"Lancet"},{"key":"10.3802\/jgo.2026.37.e126_ref24","unstructured":"Human Protein Atlas. EGFR, cervical cancer, Human pathology [Internet]. Uppsala. Human Protein Atlas. 2025. cited 2025 Oct 29. Available from: https:\/\/www.proteinatlas.org\/ENSG00000146648-EGFR\/pathology\/cervical+cancer#ihc"},{"key":"10.3802\/jgo.2026.37.e126_ref25","doi-asserted-by":"crossref","first-page":"171.e1","DOI":"10.1016\/j.ajog.2010.09.031","volume":"204","author":"Brunner","year":"2011","journal-title":"Am J Obstet Gynecol"},{"key":"10.3802\/jgo.2026.37.e126_ref26","doi-asserted-by":"crossref","first-page":"6373","DOI":"10.3390\/cancers13246373","volume":"13","author":"Garganese","year":"2021","journal-title":"Cancers (Basel)"},{"key":"10.3802\/jgo.2026.37.e126_ref27","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.ygyno.2011.01.030","volume":"121","author":"Farley","year":"2011","journal-title":"Gynecol Oncol"},{"key":"10.3802\/jgo.2026.37.e126_ref28","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/j.ygyno.2011.05.040","volume":"122","author":"Santin","year":"2011","journal-title":"Gynecol Oncol"},{"key":"10.3802\/jgo.2026.37.e126_ref29","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.ygyno.2012.08.030","volume":"127","author":"Moore","year":"2012","journal-title":"Gynecol Oncol"},{"key":"10.3802\/jgo.2026.37.e126_ref30","doi-asserted-by":"crossref","first-page":"2530","DOI":"10.1158\/1078-0432.CCR-14-2368","volume":"21","author":"de la Rochefordiere","year":"2015","journal-title":"Clin Cancer Res"}],"container-title":["Journal of Gynecologic Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/ejgo.org\/pdf\/10.3802\/jgo.2026.37.e126","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ejgo.org\/DOIx.php?id=10.3802\/jgo.2026.37.e126","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ejgo.org\/DOIx.php?id=10.3802\/jgo.2026.37.e126","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T05:49:26Z","timestamp":1779256166000},"score":1,"resource":{"primary":{"URL":"https:\/\/ejgo.org\/DOIx.php?id=10.3802\/jgo.2026.37.e126"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":30,"URL":"https:\/\/doi.org\/10.3802\/jgo.2026.37.e126","relation":{},"ISSN":["2005-0380","2005-0399"],"issn-type":[{"value":"2005-0380","type":"print"},{"value":"2005-0399","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"assertion":[{"value":"2025-11-06","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-11","name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-04","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-18","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"\u00a9 2026. Asian Society of Gynecologic Oncology, Korean Society of Gynecologic Oncology, and Japan Society of Gynecologic Oncology","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}],"article-number":"e126"}}