{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T12:00:24Z","timestamp":1784894424307,"version":"3.55.0"},"reference-count":55,"publisher":"Korean Endocrine Society","issue":"3","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002467","name":"Dankook University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002467","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["synapse.koreamed.org"],"crossmark-restriction":false},"short-container-title":["Endocrinol Metab"],"published-print":{"date-parts":[[2016]]},"DOI":"10.3803\/enm.2016.31.3.379","type":"journal-article","created":{"date-parts":[[2016,10,4]],"date-time":"2016-10-04T02:56:28Z","timestamp":1475549788000},"page":"379","update-policy":"https:\/\/doi.org\/10.3803\/crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Recent Advances in Autoimmune Thyroid Diseases"],"prefix":"10.3803","volume":"31","author":[{"given":"Won Sang","family":"Yoo","sequence":"first","affiliation":[{"name":"Division of Endocrinology and Metabolism, Department of Internal Medicine, Dankook University College of Medicine, Cheonan, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun Kyung","family":"Chung","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism, Department of Internal Medicine, Dankook University College of Medicine, Cheonan, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2119","reference":[{"key":"10.3803\/EnM.2016.31.3.379_ref1","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.autrev.2014.10.016","volume":"14","author":"Antonelli","year":"2015","journal-title":"Autoimmun Rev"},{"key":"10.3803\/EnM.2016.31.3.379_ref2","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1093\/hmg\/ddp087","volume":"18","author":"Brand","year":"2009","journal-title":"Hum Mol Genet"},{"key":"10.3803\/EnM.2016.31.3.379_ref3","doi-asserted-by":"crossref","first-page":"3415","DOI":"10.1093\/hmg\/ddr247","volume":"20","author":"Colobran","year":"2011","journal-title":"Hum Mol Genet"},{"key":"10.3803\/EnM.2016.31.3.379_ref4","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1038\/ng1297-393","volume":"17","author":"Nagamine","year":"1997","journal-title":"Nat Genet"},{"key":"10.3803\/EnM.2016.31.3.379_ref5","doi-asserted-by":"crossref","first-page":"4747","DOI":"10.1210\/jcem.86.10.7884","volume":"86","author":"Cetani","year":"2001","journal-title":"J Clin Endocrinol Metab"},{"key":"10.3803\/EnM.2016.31.3.379_ref6","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1007\/s12026-012-8302-x","volume":"54","author":"Hasham","year":"2012","journal-title":"Immunol Res"},{"key":"10.3803\/EnM.2016.31.3.379_ref7","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.4238\/2013.April.26.4","volume":"12","author":"Ji","year":"2013","journal-title":"Genet Mol Res"},{"key":"10.3803\/EnM.2016.31.3.379_ref8","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1507\/endocrj.EJ11-0381","volume":"59","author":"Luo","year":"2012","journal-title":"Endocr J"},{"key":"10.3803\/EnM.2016.31.3.379_ref9","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1507\/endocrj.EJ12-0126","volume":"59","author":"Li","year":"2012","journal-title":"Endocr J"},{"key":"10.3803\/EnM.2016.31.3.379_ref10","doi-asserted-by":"crossref","first-page":"113","DOI":"10.3109\/08916934.2013.866101","volume":"47","author":"Zaaber","year":"2014","journal-title":"Autoimmunity"},{"key":"10.3803\/EnM.2016.31.3.379_ref11","doi-asserted-by":"crossref","first-page":"533","DOI":"10.3109\/08916934.2012.702814","volume":"45","author":"Yan","year":"2012","journal-title":"Autoimmunity"},{"key":"10.3803\/EnM.2016.31.3.379_ref12","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1007\/s10142-013-0337-0","volume":"13","author":"Xiao","year":"2013","journal-title":"Funct Integr Genomics"},{"key":"10.3803\/EnM.2016.31.3.379_ref13","doi-asserted-by":"crossref","first-page":"E719","DOI":"10.1210\/jc.2013-3539","volume":"99","author":"Santos","year":"2014","journal-title":"J Clin Endocrinol Metab"},{"key":"10.3803\/EnM.2016.31.3.379_ref14","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1089\/thy.2009.0351","volume":"20","author":"Toulis","year":"2010","journal-title":"Thyroid"},{"key":"10.3803\/EnM.2016.31.3.379_ref15","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1186\/1745-6215-15-115","volume":"15","author":"Winther","year":"2014","journal-title":"Trials"},{"key":"10.3803\/EnM.2016.31.3.379_ref16","doi-asserted-by":"crossref","first-page":"3813","DOI":"10.3390\/nu7053813","volume":"7","author":"Xu","year":"2015","journal-title":"Nutrients"},{"key":"10.3803\/EnM.2016.31.3.379_ref17","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.autrev.2014.10.008","volume":"14","author":"D'Aurizio","year":"2015","journal-title":"Autoimmun Rev"},{"key":"10.3803\/EnM.2016.31.3.379_ref18","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1530\/EJE-12-0356","volume":"167","author":"Carle","year":"2012","journal-title":"Eur J Endocrinol"},{"key":"10.3803\/EnM.2016.31.3.379_ref19","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1530\/EJE-14-0864","volume":"172","author":"Arena","year":"2015","journal-title":"Eur J Endocrinol"},{"key":"10.3803\/EnM.2016.31.3.379_ref20","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1002\/ajhb.21200","volume":"23","author":"Cepon","year":"2011","journal-title":"Am J Hum Biol"},{"key":"10.3803\/EnM.2016.31.3.379_ref21","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1089\/thy.2012.0514","volume":"23","author":"Glick","year":"2013","journal-title":"Thyroid"},{"key":"10.3803\/EnM.2016.31.3.379_ref22","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1210\/jc.2011-2003","volume":"7","author":"Zhu","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"key":"10.3803\/EnM.2016.31.3.379_ref23","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1210\/jc.2009-1719","volume":"95","author":"Figueroa-Vega","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"key":"10.3803\/EnM.2016.31.3.379_ref24","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1507\/endocrj.EJ14-0265","volume":"61","author":"Bai","year":"2014","journal-title":"Endocr J"},{"key":"10.3803\/EnM.2016.31.3.379_ref25","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1007\/BF03401282","volume":"12","author":"Hiromatsu","year":"2013","journal-title":"Hormones (Athens)"},{"key":"10.3803\/EnM.2016.31.3.379_ref26","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1507\/endocrj.EJ15-0175","volume":"62","author":"Takeshima","year":"2015","journal-title":"Endocr J"},{"key":"10.3803\/EnM.2016.31.3.379_ref27","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1159\/000356507","volume":"2","author":"Pearce","year":"2013","journal-title":"Eur Thyroid J"},{"key":"10.3803\/EnM.2016.31.3.379_ref28","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1159\/000438909","volume":"4","author":"Wiersinga","year":"2015","journal-title":"Eur Thyroid J"},{"key":"10.3803\/EnM.2016.31.3.379_ref29","doi-asserted-by":"crossref","first-page":"3353","DOI":"10.1210\/jc.2014-1250","volume":"99","author":"Collet","year":"2014","journal-title":"J Clin Endocrinol Metab"},{"key":"10.3803\/EnM.2016.31.3.379_ref30","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1210\/jcem.87.3.8165","volume":"87","author":"Andersen","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"10.3803\/EnM.2016.31.3.379_ref31","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1001\/jamainternmed.2015.0930","volume":"175","author":"Asvold","year":"2015","journal-title":"JAMA Intern Med"},{"key":"10.3803\/EnM.2016.31.3.379_ref32","unstructured":"TRUST project. Thyroid hormone replacement for subclinical hypothyroidism trial (TRUST) [Internet]. TRUST project. 2012. cited 2016 Jul 24. Available from: http:\/\/www.trustthyroidtrial.com"},{"key":"10.3803\/EnM.2016.31.3.379_ref33","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1001\/archinte.160.4.526","volume":"160","author":"Canaris","year":"2000","journal-title":"Arch Intern Med"},{"key":"10.3803\/EnM.2016.31.3.379_ref34","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1159\/000339444","volume":"1","author":"Wiersinga","year":"2012","journal-title":"Eur Thyroid J"},{"key":"10.3803\/EnM.2016.31.3.379_ref35","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1210\/er.2009-0040","volume":"32","author":"Piehl","year":"2011","journal-title":"Endocr Rev"},{"key":"10.3803\/EnM.2016.31.3.379_ref36","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1089\/thy.2010.0417","volume":"21","author":"Bahn Chair","year":"2011","journal-title":"Thyroid"},{"key":"10.3803\/EnM.2016.31.3.379_ref37","doi-asserted-by":"crossref","first-page":"275","DOI":"10.3803\/EnM.2013.28.4.275","volume":"28","author":"Moon","year":"2013","journal-title":"Endocrinol Metab (Seoul)"},{"key":"10.3803\/EnM.2016.31.3.379_ref38","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1111\/cen.12688","volume":"84","author":"Bartalena","year":"2016","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.3803\/EnM.2016.31.3.379_ref39","doi-asserted-by":"crossref","first-page":"620","DOI":"10.3803\/EnM.2015.30.4.620","volume":"30","author":"Yang","year":"2015","journal-title":"Endocrinol Metab (Seoul)"},{"key":"10.3803\/EnM.2016.31.3.379_ref40","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.3346\/jkms.2015.30.10.1531","volume":"30","author":"Min","year":"2015","journal-title":"J Korean Med Sci"},{"key":"10.3803\/EnM.2016.31.3.379_ref41","doi-asserted-by":"crossref","first-page":"3995","DOI":"10.1210\/jc.2013-4466","volume":"99","author":"Okamura","year":"2014","journal-title":"J Clin Endocrinol Metab"},{"key":"10.3803\/EnM.2016.31.3.379_ref42","doi-asserted-by":"crossref","first-page":"694023","DOI":"10.1155\/2015\/694023","volume":"2015","author":"Zheng","year":"2015","journal-title":"Int J Endocrinol"},{"key":"10.3803\/EnM.2016.31.3.379_ref43","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1159\/000438750","volume":"4","author":"Biondi","year":"2015","journal-title":"Eur Thyroid J"},{"key":"10.3803\/EnM.2016.31.3.379_ref44","doi-asserted-by":"crossref","first-page":"e7895","DOI":"10.1136\/bmj.e7895","volume":"345","author":"Selmer","year":"2012","journal-title":"BMJ"},{"key":"10.3803\/EnM.2016.31.3.379_ref45","doi-asserted-by":"crossref","first-page":"2055","DOI":"10.1001\/jama.2015.5161","volume":"313","author":"Blum","year":"2015","journal-title":"JAMA"},{"key":"10.3803\/EnM.2016.31.3.379_ref46","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1507\/endocrj.K10E-262","volume":"58","author":"Konishi","year":"2011","journal-title":"Endocr J"},{"key":"10.3803\/EnM.2016.31.3.379_ref47","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1097\/MED.0000000000000088","volume":"21","author":"Laurberg","year":"2014","journal-title":"Curr Opin Endocrinol Diabetes Obes"},{"key":"10.3803\/EnM.2016.31.3.379_ref48","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1530\/EJE-14-0704","volume":"172","author":"Liu","year":"2015","journal-title":"Eur J Endocrinol"},{"key":"10.3803\/EnM.2016.31.3.379_ref49","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.ando.2015.08.004","volume":"76","author":"Liu","year":"2015","journal-title":"Ann Endocrinol (Paris)"},{"key":"10.3803\/EnM.2016.31.3.379_ref50","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1210\/jc.2015-3644","volume":"101","author":"Vos","year":"2016","journal-title":"J Clin Endocrinol Metab"},{"key":"10.3803\/EnM.2016.31.3.379_ref51","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1210\/jc.2015-3695","volume":"101","author":"Ladenson","year":"2016","journal-title":"J Clin Endocrinol Metab"},{"key":"10.3803\/EnM.2016.31.3.379_ref52","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/B978-0-12-381296-4.00022-1","volume":"485","author":"Sanders","year":"2010","journal-title":"Methods Enzymol"},{"key":"10.3803\/EnM.2016.31.3.379_ref53","doi-asserted-by":"crossref","first-page":"4287","DOI":"10.1210\/jc.2012-3080","volume":"97","author":"Gershengorn","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"key":"10.3803\/EnM.2016.31.3.379_ref54","doi-asserted-by":"crossref","first-page":"2314","DOI":"10.1111\/j.1476-5381.2011.01709.x","volume":"165","author":"van Koppen","year":"2012","journal-title":"Br J Pharmacol"},{"key":"10.3803\/EnM.2016.31.3.379_ref55","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1210\/en.2013-1835","volume":"155","author":"Neumann","year":"2014","journal-title":"Endocrinology"}],"container-title":["Endocrinology and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/synapse.koreamed.org\/pdf\/10.3803\/EnM.2016.31.3.379","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/synapse.koreamed.org\/DOIx.php?id=10.3803\/EnM.2016.31.3.379","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/synapse.koreamed.org\/DOIx.php?id=10.3803\/EnM.2016.31.3.379","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,30]],"date-time":"2020-06-30T08:49:55Z","timestamp":1593506995000},"score":1,"resource":{"primary":{"URL":"http:\/\/e-enm.org\/journal\/view.php?doi=10.3803\/EnM.2016.31.3.379"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":55,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.3803\/enm.2016.31.3.379","relation":{},"ISSN":["2093-596X","2093-5978"],"issn-type":[{"value":"2093-596X","type":"print"},{"value":"2093-5978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]},"assertion":[{"value":"https:\/\/synapse.koreamed.orgDOIx.php?id=10.3803\/EnM.2016.31.3.379","URL":"https:\/\/synapse.koreamed.orgDOIx.php?id=10.3803\/EnM.2016.31.3.379","name":"synapse","label":"Synapse","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"http:\/\/e-enm.org\/DOIx.php?id=10.3803\/EnM.2016.31.3.379","URL":"http:\/\/e-enm.org\/DOIx.php?id=10.3803\/EnM.2016.31.3.379","name":"the_journal","label":"the Journal","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"2016-07-01","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-07-06","name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-07-13","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-08-26","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"Copyright \u00a9 2016 Korean Endocrine Society","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}