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In target tissues, such as the retina, heart, and skeletal muscle, it functions as an essential antioxidant, osmolyte, and antiapoptotic agent. Taurine is also involved in energy metabolism and calcium homeostasis. Taurine plays a considerable role in bone growth and development, and high-profile reports have demonstrated the importance of its metabolism for bone health. However, these reports have not been collated for more than 10 years. Therefore, this review focuses on taurine\u2013bone interactions and covers recently discovered aspects of taurine\u2019s effects on osteoblastogenesis, osteoclastogenesis, bone structure, and bone pathologies (e.g., osteoporosis and fracture healing), with due attention to the taurine\u2013cartilage relationship.<\/jats:p>","DOI":"10.3803\/enm.2022.1443","type":"journal-article","created":{"date-parts":[[2022,8,8]],"date-time":"2022-08-08T08:01:32Z","timestamp":1659945692000},"page":"559-574","update-policy":"https:\/\/doi.org\/10.3803\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["A Key Metabolic Regulator of Bone and Cartilage Health"],"prefix":"10.3803","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5834-3960","authenticated-orcid":true,"given":"Elizabeth","family":"P\u00e9rez-Hern\u00e1ndez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jes\u00fas 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