{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T00:34:19Z","timestamp":1793406859097,"version":"4.5.0"},"reference-count":27,"publisher":"Korean Endocrine Society","issue":"4","license":[{"start":{"date-parts":[[2023,8,16]],"date-time":"2023-08-16T00:00:00Z","timestamp":1692144000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003710","name":"Korea Health Industry Development Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003710","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003625","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["HI21C0032"],"award-info":[{"award-number":["HI21C0032"]}],"id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003625","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["HI22C0049"],"award-info":[{"award-number":["HI22C0049"]}],"id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["e-enm.org"],"crossmark-restriction":true},"short-container-title":["Endocrinol Metab"],"published-print":{"date-parts":[[2023,8,31]]},"abstract":"<jats:p>Adrenal incidentalomas represent an increasingly common clinical conundrum with significant implications for patients. The revised 2023 European Society of Endocrinology (ESE) guideline incorporates cutting-edge evidence for managing adrenal incidentalomas. This paper provides a concise review of the updated contents of the revised guideline. In the 2023 guideline, in patients without signs and symptoms of overt Cushing\u2019s syndrome, a post-dexamethasone cortisol level above 50 nmol\/L (&gt;1.8 \u03bcg\/dL) should be considered as mild autonomous cortisol secretion. Regarding the criteria of benign adrenal adenomas, a homogeneous adrenal mass with \u226410 Hounsfield units on non-contrast computed tomography requires no further follow-up, irrespective of its size. The updated guideline also discusses steroid metabolomics using tandem mass spectrometry to discriminate malignancy. It underscores the importance of high-volume surgeons performing adrenalectomy and emphasizes the pivotal role of a multidisciplinary team approach in deciding the treatment plan for indeterminate adrenal masses. The guideline advocates for more proactive surgical treatment for indeterminate adrenal masses in young patients (&lt;40 years) and pregnant women. This review of the 2023 ESE guideline underscores the ongoing evolution of the adrenal incidentaloma management landscape, emphasizing the need for further research and adaptation of diagnostic and therapeutic strategies.<\/jats:p>","DOI":"10.3803\/enm.2023.1779","type":"journal-article","created":{"date-parts":[[2023,8,16]],"date-time":"2023-08-16T04:37:55Z","timestamp":1692160675000},"page":"373-380","update-policy":"https:\/\/doi.org\/10.3803\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Recent Updates on the Management of Adrenal Incidentalomas"],"prefix":"10.3803","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5719-1539","authenticated-orcid":true,"given":"Seung Shin","family":"Park","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1932-0234","authenticated-orcid":true,"given":"Jung 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steroid metabolomics for the differential diagnosis of adrenal incidentalomas in the EURINEACT study: a prospective test validation study","author":"Bancos","year":"2020"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1530\/eje-17-1056"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines8090314"},{"key":"ref23","first-page":"200","volume-title":"Diagnosis of a malignant adrenal mass: the role of urinary steroid metabolite profiling","author":"Bancos","year":"2017"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1007\/s12672-015-0224-3"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1530\/eje-18-0782"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.3803\/enm.2021.1149"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2011-1565"}],"container-title":["Endocrinology and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.e-enm.org\/upload\/pdf\/enm-2023-1779.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.e-enm.org\/journal\/view.php?doi=10.3803\/EnM.2023.1779","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.e-enm.org\/upload\/pdf\/enm-2023-1779.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T07:28:19Z","timestamp":1693466899000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.e-enm.org\/journal\/view.php?doi=10.3803\/EnM.2023.1779"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,31]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,8]]}},"URL":"https:\/\/doi.org\/10.3803\/enm.2023.1779","relation":{},"ISSN":["2093-596X","2093-5978"],"issn-type":[{"value":"2093-596X","type":"print"},{"value":"2093-5978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,31]]},"assertion":[{"value":"2023-07-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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