{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T12:53:27Z","timestamp":1788785607115,"version":"build-2803163510"},"reference-count":198,"publisher":"Korean Endocrine Society","issue":"4","license":[{"start":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Korean Thyroid Association"},{"name":"National Cancer Care Guideline Research Grant","award":["2112570"],"award-info":[{"award-number":["2112570"]}]},{"name":"Patient-Centered Clinical Research Coordinating Center","award":["RS-2024-00398702"],"award-info":[{"award-number":["RS-2024-00398702"]}]},{"DOI":"10.13039\/501100003625","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["e-enm.org"],"crossmark-restriction":true},"short-container-title":["Endocrinol Metab"],"published-print":{"date-parts":[[2026,8,31]]},"abstract":"<jats:p>In patients with differentiated thyroid cancer, initial recurrence-risk stratification based on clinical, histopathological, and perioperative findings remains central to management during the first 1\u20132 years after initial treatment. Ongoing risk stratification (ORS) complements this initial assessment by continuously integrating longitudinal clinical data and treatment response, thereby refining long-term prognostic assessment and supporting individualized risk-adapted management. Building on the 2024 Korean Thyroid Association (KTA) guidelines, the 2026 KTA guideline incorporates new evidence from large Korean multicenter cohorts and comprehensive systematic reviews. The updated recommendations reinforce the continued application of ORS and provide more specific guidance on risk-adapted thyroid-stimulating hormone (TSH) targets, surveillance strategies for recurrence detection, and long-term follow-up tailored to individual recurrence risk and treatment response. Consistent with the evolving paradigm toward risk-adapted and individualized management, this revision updates recommendations regarding target serum TSH levels, serum thyroglobulin thresholds for response assessment and long-term surveillance, and follow-up intervals based on both initial-risk category and the ORS response category. These evidence-based recommendations aim to minimize unnecessary treatment and excessive surveillance in the majority of patients who have an excellent prognosis after initial therapy while ensuring individualized long-term management for patients who require closer surveillance or additional therapeutic intervention.<\/jats:p>","DOI":"10.3803\/enm.2026.3149","type":"journal-article","created":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T08:19:21Z","timestamp":1788164361000},"page":"493-534","update-policy":"https:\/\/doi.org\/10.3803\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Korean Thyroid Association Guidelines on the Management of Differentiated Thyroid Cancers, Part II: Follow-up Surveillance after Initial Treatment 2026"],"prefix":"10.3803","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0098-0873","authenticated-orcid":true,"given":"Eun Kyung","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, National Cancer Center, Goyang, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6569-825X","authenticated-orcid":true,"given":"Seung Heon","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, Seoul St. Mary\u2019s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5928-0006","authenticated-orcid":true,"given":"Bon Seok","family":"Koo","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, Chungnam National University Hospital, Daejeon, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1538-8859","authenticated-orcid":true,"given":"Mijin","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Pusan National University Hospital, Busan, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9765-9340","authenticated-orcid":true,"given":"Min Joo","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9632-9457","authenticated-orcid":true,"given":"Bo Hyun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Pusan National University Hospital, Busan, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0882-9177","authenticated-orcid":true,"given":"Ji Won","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, Chungnam National University Sejong Hospital, Sejong, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6422-1652","authenticated-orcid":true,"given":"Dong Gyu","family":"Na","sequence":"additional","affiliation":[{"name":"Department of Radiology, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0751-0965","authenticated-orcid":true,"given":"Sohyun","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, National Cancer Center, Goyang, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2962-3642","authenticated-orcid":true,"given":"Ji-In","family":"Bang","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9160-3541","authenticated-orcid":true,"given":"Kyorim","family":"Back","sequence":"additional","affiliation":[{"name":"Department of Surgery, Chung-Ang University Gwangmyeong Hospital, Gwangmyeong, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9779-9060","authenticated-orcid":true,"given":"Youngduk","family":"Seo","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Chungnam National University Sejong Hospital, Sejong, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2114-8085","authenticated-orcid":true,"given":"Young-Ik","family":"Son","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4603-1999","authenticated-orcid":true,"given":"Young Shin","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1048-7978","authenticated-orcid":true,"given":"Dong Yeob","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0187-9777","authenticated-orcid":true,"given":"Jong-hyuk","family":"Ahn","sequence":"additional","affiliation":[{"name":"Department of Surgery, Chung-Ang University Hospital, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2737-6759","authenticated-orcid":true,"given":"Hwa Young","family":"Ahn","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Chung-Ang University Hospital, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8967-8923","authenticated-orcid":true,"given":"So Won","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5135-2474","authenticated-orcid":true,"given":"Ho-Ryun","family":"Won","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, Chungnam National University Sejong Hospital, Sejong, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2314-4184","authenticated-orcid":true,"given":"Won Sang","family":"Yoo","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Dankook University Hospital, Cheonan, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3172-3159","authenticated-orcid":true,"given":"Min Kyoung","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Radiology, Yeouido St. Mary\u2019s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7196-5366","authenticated-orcid":true,"given":"Sang-Woo","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Kyungpook National University Chilgok Hospital, Daegu, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9074-8087","authenticated-orcid":true,"given":"Jeongmin","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Eunpyeong St. Mary\u2019s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3929-6254","authenticated-orcid":true,"given":"Ji Ye","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Radiology, Seoul National University Hospital, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0995-6482","authenticated-orcid":true,"given":"Dong-Jun","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Seoul St. Mary\u2019s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4418-1857","authenticated-orcid":true,"given":"Ki-Wook","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9327-9810","authenticated-orcid":true,"given":"Ari","family":"Chong","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Chosun University Hospital, Gwangju, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2607-1686","authenticated-orcid":true,"given":"Jin Hyang","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Surgery, Kyungpook National University Chilgok Hospital, Daegu, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7394-3830","authenticated-orcid":true,"given":"Sun Wook","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4599-2889","authenticated-orcid":true,"given":"Yoon Young","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5519-6982","authenticated-orcid":true,"given":"Chae Moon","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Kyungpook National University Hospital, Daegu, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3671-6364","authenticated-orcid":true,"given":"Young Joo","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Korean Thyroid Association Guideline Committee on the Management of Thyroid Nodule and Cancer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2119","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.11106\/ijt.2024.17.1.115","type":"journal-article"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.11106\/ijt.2026.19.1.1","type":"journal-article"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.139.4.390","type":"journal-article"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1677\/erc.1.00892","type":"journal-article"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097\/med.0000000000000826","type":"journal-article"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.11106\/ijt.2024.17.1.68","type":"journal-article"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2009.1601","type":"journal-article"},{"key":"ref8","first-page":"1","type":"journal-article","volume-title":"2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the American Thyroid Association guidelines task force on thyroid nodules and differentiated thyroid cancer","author":"Haugen","year":"2016"},{"key":"ref9","first-page":"59","type":"journal-article","volume-title":"2016 Revised Korean Thyroid Association management guidelines for patients with thyroid nodules and thyroid cancer","author":"Yi","year":"2016"},{"key":"ref10","first-page":"841","type":"journal-article","volume-title":"2025 American Thyroid Association management guidelines for adult patients with differentiated thyroid cancer","author":"Ringel","year":"2025"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2010.0178","type":"journal-article"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecl.2008.02.008","type":"journal-article"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecl.2014.02.010","type":"journal-article"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-009-1315-6","type":"journal-article"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2016.0479","type":"journal-article"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2012.04342.x","type":"journal-article"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2017.0578","type":"journal-article"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2010.0355","type":"journal-article"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2021.0666","type":"journal-article"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdz400","type":"journal-article"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1177\/10507256251409134","type":"journal-article"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1530\/eje-11-0466","type":"journal-article"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2011.0232","type":"journal-article"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/591285","type":"journal-article"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1530\/eje-13-0524","type":"journal-article"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1016\/s2213-8587(18)30113-x","type":"journal-article"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2011.0322","type":"journal-article"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2011.0214","type":"journal-article"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2015-4290","type":"journal-article"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2016.0477","type":"journal-article"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2021.764258","type":"journal-article"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2012-1123","type":"journal-article"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1530\/erc-15-0458","type":"journal-article"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1530\/eje-13-0386","type":"journal-article"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgaa297","type":"journal-article"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1159\/000442048","type":"journal-article"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-020-02414-1","type":"journal-article"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2010-0762","type":"journal-article"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2011.04002.x","type":"journal-article"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/398194","type":"journal-article"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1111\/cen.13721","type":"journal-article"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2018.0046","type":"journal-article"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgaa152","type":"journal-article"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2021.0209","type":"journal-article"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.21873\/anticanres.16070","type":"journal-article"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800770329","type":"journal-article"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.1530\/erc-19-0213","type":"journal-article"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2017.0199","type":"journal-article"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.3803\/enm.2020.943","type":"journal-article"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.1097\/mlg.0b013e318162cae9","type":"journal-article"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2010-0063","type":"journal-article"},{"key":"ref52","first-page":"2049","type":"journal-article","volume-title":"The outcomes of first reoperation for locoregionally recurrent\/persistent papillary thyroid carcinoma in patients who initially underwent total thyroidectomy and remnant ablation","author":"Yim","year":"2011"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.1007\/s11154-023-09857-7","type":"journal-article"},{"key":"ref54","doi-asserted-by":"publisher","DOI":"10.1172\/jci85271","type":"journal-article"},{"key":"ref55","first-page":"652","type":"journal-article","volume-title":"Frequency of TERT promoter mutations in real-world analysis of 2,092 thyroid carcinoma patients","author":"Yang","year":"2022"},{"key":"ref56","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14194928","type":"journal-article"},{"key":"ref57","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2011.04272.x","type":"journal-article"},{"key":"ref58","doi-asserted-by":"publisher","DOI":"10.1080\/078538902321117760","type":"journal-article"},{"key":"ref59","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2007-2215","type":"journal-article"},{"key":"ref60","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2007-2228","type":"journal-article"},{"key":"ref61","doi-asserted-by":"publisher","DOI":"10.1056\/nejmcp010145","type":"journal-article"},{"key":"ref62","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2009.0311","type":"journal-article"},{"key":"ref63","doi-asserted-by":"publisher","DOI":"10.1210\/jc.81.12.4224","type":"journal-article"},{"key":"ref64","doi-asserted-by":"publisher","DOI":"10.1111\/cen.13519","type":"journal-article"},{"key":"ref65","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgab576","type":"journal-article"},{"key":"ref66","doi-asserted-by":"publisher","DOI":"10.1089\/105072502760043503","type":"journal-article"},{"key":"ref67","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecl.2018.10.008","type":"journal-article"},{"key":"ref68","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2006.16.583","type":"journal-article"},{"key":"ref69","doi-asserted-by":"publisher","DOI":"10.11005\/jbm.2019.26.1.51","type":"journal-article"},{"key":"ref70","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2014.0287","type":"journal-article"},{"key":"ref71","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgab539","type":"journal-article"},{"key":"ref72","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2020-043007","type":"journal-article"},{"key":"ref73","doi-asserted-by":"publisher","DOI":"10.1177\/10507256261431793","type":"journal-article"},{"key":"ref74","doi-asserted-by":"publisher","DOI":"10.4174\/astr.2024.106.1.19","type":"journal-article"},{"key":"ref75","doi-asserted-by":"publisher","DOI":"10.3803\/enm.2025.2465","type":"journal-article"},{"key":"ref76","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2015-1346","type":"journal-article"},{"key":"ref77","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2010-0161","type":"journal-article"},{"key":"ref78","doi-asserted-by":"publisher","DOI":"10.1515\/fco-2015-0010","type":"journal-article"},{"key":"ref79","doi-asserted-by":"publisher","DOI":"10.4158\/ep-2018-0393","type":"journal-article"},{"key":"ref80","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2018.7754","type":"journal-article"},{"key":"ref81","doi-asserted-by":"publisher","DOI":"10.1200\/jco.2013.49.1043","type":"journal-article"},{"key":"ref82","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2024.0330","type":"journal-article"},{"key":"ref83","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2023.0711","type":"journal-article"},{"key":"ref84","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2024.0346","type":"journal-article"},{"key":"ref85","volume-title":"","author":"Feldt-Rasmussen","type":"web-resource"},{"key":"ref86","doi-asserted-by":"publisher","DOI":"10.3803\/enm.2024.1934","type":"journal-article"},{"key":"ref87","doi-asserted-by":"publisher","DOI":"10.11106\/ijt.2023.16.2.166","type":"journal-article"},{"key":"ref88","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14061470","type":"journal-article"},{"key":"ref89","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2021.0404","type":"journal-article"},{"key":"ref90","doi-asserted-by":"publisher","DOI":"10.1002\/hed.26075","type":"journal-article"},{"key":"ref91","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgaf463","type":"journal-article"},{"key":"ref92","doi-asserted-by":"publisher","DOI":"10.1159\/000511708","type":"journal-article"},{"key":"ref93","volume-title":"Thyroid cancer: assessment and management [NICE Guideline No. 230] [Internet]","year":"2022","type":"web-resource"},{"key":"ref94","doi-asserted-by":"publisher","DOI":"10.3803\/enm.2019.34.2.150","type":"journal-article"},{"key":"ref95","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2017.04.039","type":"journal-article"},{"key":"ref96","doi-asserted-by":"publisher","DOI":"10.4158\/ep12334.or","type":"journal-article"},{"key":"ref97","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2020.00520","type":"journal-article"},{"key":"ref98","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgad517","type":"journal-article"},{"key":"ref99","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-023-03548-8","type":"journal-article"},{"key":"ref100","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2022.852347","type":"journal-article"},{"key":"ref101","doi-asserted-by":"publisher","DOI":"10.1111\/cen.14698","type":"journal-article"},{"key":"ref102","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2021.0033","type":"journal-article"},{"key":"ref103","doi-asserted-by":"publisher","DOI":"10.1055\/a-2084-3408","type":"journal-article"},{"key":"ref104","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2011.09.013","type":"journal-article"},{"key":"ref105","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-015-3564-2","type":"journal-article"},{"key":"ref106","doi-asserted-by":"publisher","DOI":"10.3803\/enm.2023.1701","type":"journal-article"},{"key":"ref107","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2308652121","type":"journal-article"},{"key":"ref108","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2013.258","type":"journal-article"},{"key":"ref109","first-page":"746","type":"journal-article","volume-title":"Predicting optimal combination LT4 + LT3 therapy for hypothyroidism based on residual thyroid function","author":"DiStefano J","year":"2019"},{"key":"ref110","doi-asserted-by":"publisher","DOI":"10.1016\/s2213-8587(22)00004-3","type":"journal-article"},{"key":"ref111","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2002-021365","type":"journal-article"},{"key":"ref112","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2265.2002.01574.x","type":"journal-article"},{"key":"ref113","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2011.2107.ed1","type":"journal-article"},{"key":"ref114","doi-asserted-by":"publisher","DOI":"10.1515\/cclm-2021-1046","type":"journal-article"},{"key":"ref115","first-page":"3615","type":"journal-article","volume-title":"Clinical review: clinical utility of thyroglobulin antibody (TgAb) measurements for patients with differentiated thyroid cancers (DTC)","author":"Spencer","year":"2011"},{"key":"ref116","doi-asserted-by":"publisher","DOI":"10.1530\/eje.1.01940","type":"journal-article"},{"key":"ref117","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2011-2812","type":"journal-article"},{"key":"ref118","doi-asserted-by":"publisher","DOI":"10.1016\/j.beem.2013.07.003","type":"journal-article"},{"key":"ref119","first-page":"4683","type":"journal-article","volume-title":"Change of serum antithyroglobulin antibody levels is useful for prediction of clinical recurrence in thyroglobulin-negative patients with differentiated thyroid carcinoma","author":"Kim","year":"2008"},{"key":"ref120","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2012.0606","type":"journal-article"},{"key":"ref121","doi-asserted-by":"publisher","DOI":"10.1210\/jc.83.4.1121","type":"journal-article"},{"key":"ref122","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-139-5_part_1-200309020-00010","type":"journal-article"},{"key":"ref123","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2019.0368","type":"journal-article"},{"key":"ref124","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2012-1533","type":"journal-article"},{"key":"ref125","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2005.02228.x","type":"journal-article"},{"key":"ref126","doi-asserted-by":"publisher","DOI":"10.1097\/rlu.0b013e318203bb84","type":"journal-article"},{"key":"ref127","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2004.02060.x","type":"journal-article"},{"key":"ref128","doi-asserted-by":"publisher","DOI":"10.3803\/enm.2025.2302","type":"journal-article"},{"key":"ref129","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2007-1404","type":"journal-article"},{"key":"ref130","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2005-0492","type":"journal-article"},{"key":"ref131","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2010.03898.x","type":"journal-article"},{"key":"ref132","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1269881","type":"journal-article"},{"key":"ref133","first-page":"e219","type":"journal-article","volume-title":"The use of ultrasensitive thyroglobulin assays reduces but does not abolish the need for TSH stimulation in patients with differentiated thyroid carcinoma","author":"Castagna","year":"2011"},{"key":"ref134","doi-asserted-by":"publisher","DOI":"10.1677\/erc-10-0292","type":"journal-article"},{"key":"ref135","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2011.0522","type":"journal-article"},{"key":"ref136","doi-asserted-by":"publisher","DOI":"10.1530\/erc-21-0012","type":"journal-article"},{"key":"ref137","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgac646","type":"journal-article"},{"key":"ref138","first-page":"1126","volume-title":"AIUM Practice Guideline for the performance of thyroid and parathyroid ultrasound examination","year":"2003","type":"journal-article"},{"key":"ref139","doi-asserted-by":"publisher","DOI":"10.3348\/kjr.2020.0578","type":"journal-article"},{"key":"ref140","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2014.0096","type":"journal-article"},{"key":"ref141","doi-asserted-by":"publisher","DOI":"10.1530\/eje-13-0888","type":"journal-article"},{"key":"ref142","doi-asserted-by":"publisher","DOI":"10.1111\/coa.13103","type":"journal-article"},{"key":"ref143","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacr.2019.02.004","type":"journal-article"},{"key":"ref144","doi-asserted-by":"publisher","DOI":"10.1159\/000354537","type":"journal-article"},{"key":"ref145","doi-asserted-by":"publisher","DOI":"10.3348\/kjr.2019.0755","type":"journal-article"},{"key":"ref146","doi-asserted-by":"publisher","DOI":"10.3348\/kjr.2022.0358","type":"journal-article"},{"key":"ref147","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14092106","type":"journal-article"},{"key":"ref148","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2021201596","type":"journal-article"},{"key":"ref149","doi-asserted-by":"publisher","DOI":"10.3348\/kjr.2021.0713","type":"journal-article"},{"key":"ref150","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2016.0252","type":"journal-article"},{"key":"ref151","doi-asserted-by":"publisher","DOI":"10.1007\/s40618-018-0884-2","type":"journal-article"},{"key":"ref152","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2011.0011","type":"journal-article"},{"key":"ref153","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2012-1553","type":"journal-article"},{"key":"ref154","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13061338","type":"journal-article"},{"key":"ref155","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2008.03297.x","type":"journal-article"},{"key":"ref156","first-page":"e17859","type":"journal-article","volume-title":"Diagnostic value of cytology, thyroglobulin, and combination of them in fine-needle aspiration of metastatic lymph nodes in patients with differentiated thyroid cancer: a systematic review and network meta-analysis","author":"Xu","year":"2019"},{"key":"ref157","first-page":"274","type":"journal-article","volume-title":"The influence of thyroid status, serum Tg, TSH, and TgAb on FNA-Tg in cervical metastatic lymph nodes of papillary thyroid carcinoma","author":"Sun","year":"2021"},{"key":"ref158","doi-asserted-by":"publisher","DOI":"10.1159\/000479682","type":"journal-article"},{"key":"ref159","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2012-3291","type":"journal-article"},{"key":"ref160","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2014-1098","type":"journal-article"},{"key":"ref161","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2013.0244","type":"journal-article"},{"key":"ref162","doi-asserted-by":"publisher","DOI":"10.1186\/1742-6413-5-1","type":"journal-article"},{"key":"ref163","doi-asserted-by":"publisher","DOI":"10.1530\/eje-07-0749","type":"journal-article"},{"key":"ref164","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6890-13-7","type":"journal-article"},{"key":"ref165","doi-asserted-by":"publisher","DOI":"10.3803\/enm.2023.1669","type":"journal-article"},{"key":"ref166","doi-asserted-by":"publisher","DOI":"10.3233\/ch-221680","type":"journal-article"},{"key":"ref167","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2021.799956","type":"journal-article"},{"key":"ref168","doi-asserted-by":"publisher","DOI":"10.3348\/kjr.2021.0772","type":"journal-article"},{"key":"ref169","doi-asserted-by":"publisher","DOI":"10.14366\/usg.21221","type":"journal-article"},{"key":"ref170","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-021-08321-x","type":"journal-article"},{"key":"ref171","first-page":"929","type":"journal-article","volume-title":"Tracheal invasion by thyroid carcinoma: prediction using MR imaging","author":"Wang","year":"2001"},{"key":"ref172","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.87.4.8274","type":"journal-article"},{"key":"ref173","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-012-2310-x","type":"journal-article"},{"key":"ref174","doi-asserted-by":"publisher","DOI":"10.1097\/rlu.0000000000004953","type":"journal-article"},{"key":"ref175","doi-asserted-by":"publisher","DOI":"10.4183\/aeb.2021.337","type":"journal-article"},{"key":"ref176","first-page":"107","type":"journal-article","volume-title":"Sensitivity of preparation with rhTSH or thyroid hormone withdrawal using \u00b9\u00b3\u00b9I-whole body scans to identify metastases of differentiated thyroid cancer","author":"Liepe","year":"2015"},{"key":"ref177","doi-asserted-by":"publisher","DOI":"10.1530\/eje-19-0261","type":"journal-article"},{"key":"ref178","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2023.0264","type":"journal-article"},{"key":"ref179","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/856189","type":"journal-article"},{"key":"ref180","doi-asserted-by":"publisher","DOI":"10.1016\/j.diii.2021.04.004","type":"journal-article"},{"key":"ref181","first-page":"45","type":"journal-article","volume-title":"No longer well-differentiated: diagnostic criteria and clinical importance of poorly differentiated\/high-grade thyroid carcinoma","author":"Cracolici","year":"2023"},{"key":"ref182","doi-asserted-by":"publisher","DOI":"10.1530\/eje-10-0256","type":"journal-article"},{"key":"ref183","doi-asserted-by":"publisher","DOI":"10.1007\/s12149-011-0545-4","type":"journal-article"},{"key":"ref184","doi-asserted-by":"publisher","DOI":"10.1007\/s13139-015-0378-5","type":"journal-article"},{"key":"ref185","doi-asserted-by":"publisher","DOI":"10.1007\/s12149-013-0801-x","type":"journal-article"},{"key":"ref186","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics11071264","type":"journal-article"},{"key":"ref187","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinimag.2007.07.010","type":"journal-article"},{"key":"ref188","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0218416","type":"journal-article"},{"key":"ref189","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2021.648658","type":"journal-article"},{"key":"ref190","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2012.0081","type":"journal-article"},{"key":"ref191","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgab278","type":"journal-article"},{"key":"ref192","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2019-00962","type":"journal-article"},{"key":"ref193","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2003-031521","type":"journal-article"},{"key":"ref194","first-page":"893","type":"journal-article","volume-title":"Postoperative thyroglobulin and neck ultrasound in the risk restratification and decision to perform 131I ablation","author":"Matrone","year":"2017"},{"key":"ref195","doi-asserted-by":"publisher","DOI":"10.1007\/s40618-019-01044-3","type":"journal-article"},{"key":"ref196","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-021-02647-8","type":"journal-article"},{"key":"ref197","doi-asserted-by":"publisher","DOI":"10.1007\/s12149-022-01799-5","type":"journal-article"},{"key":"ref198","doi-asserted-by":"publisher","DOI":"10.11106\/ijt.2024.17.1.182","type":"journal-article"}],"container-title":["Endocrinology and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/e-enm.org\/upload\/pdf\/enm-2026-3149.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/e-enm.org\/journal\/view.php?doi=10.3803\/EnM.2026.3149","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/e-enm.org\/upload\/pdf\/enm-2026-3149.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T04:07:15Z","timestamp":1788754035000},"score":1,"resource":{"primary":{"URL":"http:\/\/e-enm.org\/journal\/view.php?doi=10.3803\/EnM.2026.3149"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,31]]},"references-count":198,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,8]]}},"URL":"https:\/\/doi.org\/10.3803\/enm.2026.3149","relation":{},"ISSN":["2093-596X","2093-5978"],"issn-type":[{"value":"2093-596X","type":"print"},{"value":"2093-5978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,31]]},"assertion":[{"value":"2026-05-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-31","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-31","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}