{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T07:34:33Z","timestamp":1771054473696,"version":"3.50.1"},"reference-count":79,"publisher":"Informa UK Limited","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Postgraduate Medicine"],"published-print":{"date-parts":[[2010,7]]},"DOI":"10.3810\/pgm.2010.07.2175","type":"journal-article","created":{"date-parts":[[2010,7,30]],"date-time":"2010-07-30T11:01:59Z","timestamp":1280487719000},"page":"49-65","source":"Crossref","is-referenced-by-count":24,"title":["Use of Selective Serotonin Reuptake Inhibitors during Pregnancy and Risk of Major and Cardiovascular Malformations: An Update"],"prefix":"10.1080","volume":"122","author":[{"given":"Marco","family":"Tuccori","sequence":"first","affiliation":[{"name":"Unit of Pharmacology, University Hospital of Pisa, Pisa, Italy"},{"name":"Tuscan Regional Centre of Pharmacovigilance, Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabrina","family":"Montagnani","sequence":"additional","affiliation":[{"name":"Tuscan Regional Centre of Pharmacovigilance, Pisa, Italy"},{"name":"Interdepartmental Centre for Research in Clinical Pharmacology and Experimental Therapeutics, University of Pisa, Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arianna","family":"Testi","sequence":"additional","affiliation":[{"name":"Tuscan Regional Centre of Pharmacovigilance, Pisa, Italy"},{"name":"Pharmaceutical Unit, Regional Health System, Health District of Pisa, Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisa","family":"Ruggiero","sequence":"additional","affiliation":[{"name":"Tuscan Regional Centre of Pharmacovigilance, Pisa, Italy"},{"name":"Pharmaceutical Unit, University Hospital of Pisa, Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefania","family":"Mantarro","sequence":"additional","affiliation":[{"name":"Interdepartmental Centre for Research in Clinical Pharmacology and Experimental Therapeutics, University of Pisa, Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carla","family":"Scollo","sequence":"additional","affiliation":[{"name":"Interdepartmental Centre for Research in Clinical Pharmacology and Experimental Therapeutics, University of Pisa, Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra","family":"Pergola","sequence":"additional","affiliation":[{"name":"Interdepartmental Centre for Research in Clinical Pharmacology and Experimental Therapeutics, University of Pisa, Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matteo","family":"Fornai","sequence":"additional","affiliation":[{"name":"Division of Pharmacology, Department of Internal Medicine, University of Pisa, Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Antonioli","sequence":"additional","affiliation":[{"name":"Interdepartmental Centre for Research in Clinical Pharmacology and Experimental Therapeutics, University of Pisa, Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rocchina","family":"Colucci","sequence":"additional","affiliation":[{"name":"Division of Pharmacology, Department of Internal Medicine, University of Pisa, Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiberio","family":"Corona","sequence":"additional","affiliation":[{"name":"Tuscan Regional Centre of Pharmacovigilance, Pisa, Italy"},{"name":"Pharmaceutical Unit, Regional Health System, Health District of Pisa, Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Corrado","family":"Blandizzi","sequence":"additional","affiliation":[{"name":"Tuscan Regional Centre of Pharmacovigilance, Pisa, Italy"},{"name":"Interdepartmental Centre for Research in Clinical Pharmacology and Experimental Therapeutics, University of Pisa, Pisa, Italy"},{"name":"Division of Pharmacology, Department of Internal Medicine, University of Pisa, Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2015,3,13]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2009.07.009"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2003.336"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2003.08.004"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.reprotox.2005.11.006"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(89)90170-1"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.323.7307.257"},{"key":"e_1_2_1_8_1","first-page":"37","article-title":"Risks of untreated depression during pregnancy","volume":"50","author":"Bonari L","year":"2004","unstructured":". Bonari L, Bennett H, Einarson A, Koren G. Risks of untreated depression during pregnancy. Can Fam Physician. 2004;50:37\u201339","journal-title":"Can Fam Physician."},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/070674370404901006"},{"key":"e_1_2_1_10_1","volume-title":"Mood and Anxiety Disorders During Pregnancy and Post Partum","author":"Cohen LS","year":"2005","unstructured":". Cohen LS, Nonacs R, eds. Mood and Anxiety Disorders During Pregnancy and Post Partum. Arlington, VA: American Psychiatric Publishing Inc; 2005"},{"issue":"10","key":"e_1_2_1_11_1","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1017\/S0033291705005350","article-title":"Psychosocial impairment in offspring of depressed parents","volume":"35","author":"Lewinsohn PM","year":"2005","unstructured":". Lewinsohn PM, Olino TM, Klein DN. Psychosocial impairment in offspring of depressed parents. Psychol Med. 2005;35(10):1493\u20131503","journal-title":"Psychol Med."},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.163.6.1001"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1192\/02-488"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ogx.0000155967.72418.6b"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.4088\/PCC.v03n0609"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0327(01)00418-9"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1192\/03-2"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2004.10.003"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00228-004-0775-7"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2003.10.024"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00228-006-0177-0"},{"key":"e_1_2_1_22_1","unstructured":". GlaxoSmithKline. Clinical Study Register. http:\/\/www.gsk-clinicalstudyregister.com\/files\/pdf\/3493.pdf. Accessed May 31 2010"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.295.14.1631"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.2006.163.6.954"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.279.8.609"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.158.10.1728"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.159.12.2055"},{"key":"e_1_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.reprotox.2006.03.019"},{"key":"e_1_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ede.0000239581.76793.ae"},{"key":"e_1_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2007.01518.x"},{"key":"e_1_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1177\/070674370905400405"},{"key":"e_1_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20615"},{"key":"e_1_2_1_33_1","doi-asserted-by":"publisher","DOI":"10.4065\/84.1.23"},{"key":"e_1_2_1_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/0890-6238(96)00057-3"},{"key":"e_1_2_1_35_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199701233360404"},{"key":"e_1_2_1_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(97)00070-7"},{"key":"e_1_2_1_37_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v67n0817"},{"key":"e_1_2_1_38_1","doi-asserted-by":"publisher","DOI":"10.1097\/jcp.0b013e31815ac4d2"},{"key":"e_1_2_1_39_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000187302.61812.53"},{"key":"e_1_2_1_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdrb.20099"},{"key":"e_1_2_1_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2007.05.003"},{"key":"e_1_2_1_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20327"},{"key":"e_1_2_1_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/pds.1463"},{"key":"e_1_2_1_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/pds.1462"},{"key":"e_1_2_1_45_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa067407"},{"key":"e_1_2_1_46_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa066584"},{"key":"e_1_2_1_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1701-2163(16)32918-8"},{"key":"e_1_2_1_48_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdrb.20144"},{"key":"e_1_2_1_49_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2007.07060879"},{"issue":"5","key":"e_1_2_1_50_1","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1111\/j.1365-2125.2008.03261.x","article-title":"Paroxetine and fluoxetine in pregnancy: a prospective, multicentre, controlled, observational study","volume":"66","author":"Diav-Citrin O","year":"2008","unstructured":". Diav-Citrin O, Shechtman S, Weinbaum D,. Paroxetine and fluoxetine in pregnancy: a prospective, multicentre, controlled, observational study. Br J Clin Pharmacol. 2008;66(5):695\u2013705","journal-title":"Br J Clin Pharmacol."},{"key":"e_1_2_1_51_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.107.042523"},{"key":"e_1_2_1_52_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b3569"},{"key":"e_1_2_1_53_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20641"},{"key":"e_1_2_1_54_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20627"},{"key":"e_1_2_1_55_1","unstructured":". Reis M K\u00e4ll\u00e9n B. Delivery outcome after maternal use of antidepressant drugs in pregnancy: an update using Swedish data [published online ahead of print January 5 2010]. Psychol Med."},{"key":"e_1_2_1_56_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1993.03500170076037"},{"key":"e_1_2_1_57_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199610033351402"},{"key":"e_1_2_1_58_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291799001270"},{"key":"e_1_2_1_59_1","doi-asserted-by":"publisher","DOI":"10.1002\/pds.1084"},{"key":"e_1_2_1_60_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002280050664"},{"key":"e_1_2_1_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2005.05.012"},{"key":"e_1_2_1_62_1","first-page":"i12","article-title":"Congenital malformations after antidepressant medication associated with paroxetine in early pregnancy?","volume":"21","author":"Schloemp S","year":"2006","unstructured":". Schloemp S, Paulus WE, Sterzik K, Stoz F. Congenital malformations after antidepressant medication associated with paroxetine in early pregnancy? Hum Reprod. 2006;21(suppl 1):i12","journal-title":"Hum Reprod."},{"key":"e_1_2_1_63_1","doi-asserted-by":"publisher","DOI":"10.1067\/mpd.2003.139"},{"key":"e_1_2_1_64_1","doi-asserted-by":"publisher","DOI":"10.2165\/00002018-200629100-00121"},{"key":"e_1_2_1_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1701-2163(16)30155-4"},{"key":"e_1_2_1_66_1","first-page":"42","article-title":"Neonatal outcomes associated with maternal antidepressant use in a population cohort of Nova Scotian pregnancies between 1993 and 2004","volume":"12","author":"Nash CM","year":"2007","unstructured":". Nash CM, O'Connell CM, Howlett AA. Neonatal outcomes associated with maternal antidepressant use in a population cohort of Nova Scotian pregnancies between 1993 and 2004. Pediatr Child Health. 2007;12(SA):42","journal-title":"Pediatr Child Health."},{"issue":"2","key":"e_1_2_1_67_1","first-page":"117","article-title":"Follow-up of 151 pregnant women exposed to antidepressant treatment (MAOI excluded) during organogenesis [in French]","volume":"49","author":"Brunel P","year":"1994","unstructured":". Brunel P, Vial T, Roche I, Bertolotti E, Evreux JC. Follow-up of 151 pregnant women exposed to antidepressant treatment (MAOI excluded) during organogenesis [in French]. Therapie. 1994;49(2):117\u2013122","journal-title":"Therapie."},{"key":"e_1_2_1_68_1","doi-asserted-by":"publisher","DOI":"10.1177\/070674370304800207"},{"key":"e_1_2_1_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.09.027"},{"key":"e_1_2_1_70_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.63.8.898"},{"key":"e_1_2_1_71_1","doi-asserted-by":"publisher","DOI":"10.3109\/00048670903559593"},{"key":"e_1_2_1_72_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.09com05478"},{"key":"e_1_2_1_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eurpsy.2007.11.001"},{"key":"e_1_2_1_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.reprotox.2009.04.005"},{"key":"e_1_2_1_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijdevneu.2003.10.002"},{"key":"e_1_2_1_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2008.10.008"},{"key":"e_1_2_1_77_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0028-1103296"},{"key":"e_1_2_1_78_1","first-page":"9","article-title":"Antidepressants","volume":"58","author":"Frazer A","year":"1997","unstructured":". Frazer A. Antidepressants. J Clin Psychiatry. 1997;58(suppl 6):9\u201325","journal-title":"J Clin Psychiatry."},{"key":"e_1_2_1_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3565(24)37161-7"},{"key":"e_1_2_1_80_1","first-page":"67","volume-title":"Schizophrenia and Mood Disorders: The New Drug Therapies in Clinical Practice","author":"Leonard BE","year":"2000","unstructured":". Leonard BE, Richelson E. Synaptic effects of antidepressants. In: Schizophrenia and Mood Disorders: The New Drug Therapies in Clinical Practice. Buckley PF, Waddington JL, eds. Boston: Butterworth-Heinemann; 2000:67\u201384"}],"container-title":["Postgraduate Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.3810\/pgm.2010.07.2175","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T09:30:01Z","timestamp":1756719001000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.3810\/pgm.2010.07.2175"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,7]]},"references-count":79,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2010,7]]}},"alternative-id":["10.3810\/pgm.2010.07.2175"],"URL":"https:\/\/doi.org\/10.3810\/pgm.2010.07.2175","relation":{},"ISSN":["0032-5481","1941-9260"],"issn-type":[{"value":"0032-5481","type":"print"},{"value":"1941-9260","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,7]]}}}