{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T12:45:08Z","timestamp":1792586708044,"version":"4.5.0"},"reference-count":0,"publisher":"The Journal of Food and Drug Analysis (JFDA), Food and Drug Administration, Taiwan (TFDA)","issue":"1","license":[{"start":{"date-parts":[[2025,3,27]],"date-time":"2025-03-27T00:00:00Z","timestamp":1743033600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Food and Drug Analysis"],"abstract":"<jats:p>This study investigated the preventive effects of a 40% ethanol extract of Hsian-tsao (40EEHT) on obesity in high-fat diet (HFD)-induced obese rats. Male Wistar rats were administered 0, 100, 200, or 500 mg\/kg of 40EEHT, resulting in reduced body weight, total body fat, and hepatic tissue weight after 8 weeks. 40EEHT also decreased adipocyte size, improved lipid profiles, alleviated oxidative stress, and enhanced hepatic antioxidant enzyme activities. Additionally, it regulated fatty acid metabolism by reducing lipogenesis and increasing lipolysis and \u03b2-oxidation, suggesting its potential as an anti-obesity dietary supplement.<\/jats:p>","DOI":"10.38212\/2224-6614.3527","type":"journal-article","created":{"date-parts":[[2025,3,30]],"date-time":"2025-03-30T10:03:56Z","timestamp":1743329036000},"page":"48-60","source":"Crossref","is-referenced-by-count":3,"title":["Protective role of Hsian-tsao ethanol extract against body fat, serum lipid profiles, and hepatic lipid profiles in high-fat diet-fed rats"],"prefix":"10.38212","volume":"33","author":[{"given":"Ching-Chang","family":"Cho","sequence":"first","affiliation":[{"name":"Department of Nutrition, Chung Shan Medical University, Taichung, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gow-Chin","family":"Yen","sequence":"additional","affiliation":[{"name":"Department of Food Science and Biotechnology, National Chung Hsing University, Taichung, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hsin-Yi","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Nutrition, Chung Shan Medical University, Taichung, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Tse","family":"Tsai","sequence":"additional","affiliation":[{"name":"Department of Nutrition, Chung Shan Medical University, Taichung, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-Tang","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Health Sciences, Chinese Culture University, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chin-Lin","family":"Hsu","sequence":"additional","affiliation":[{"name":"Department of Nutrition, Chung Shan Medical University, Taichung, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"25385","published-online":{"date-parts":[[2025,3,27]]},"container-title":["Journal of Food and Drug Analysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jfda-online.com\/cgi\/viewcontent.cgi?article=3527&amp;context=journal","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T12:15:38Z","timestamp":1792584938000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jfda-online.com\/journal\/vol33\/iss1\/5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,27]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,3,27]]}},"URL":"https:\/\/doi.org\/10.38212\/2224-6614.3527","relation":{},"ISSN":["2224-6614"],"issn-type":[{"value":"2224-6614","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,27]]}}}