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[Clinical observation on the therapeutic effect of the treatment of liver qi stagnation syndrome subthreshold depression with the acupuncture principle of \u201cTiao Qi Jie Yu\u201d] [master\u2019s thesis]. [Shanghai]: Shanghai University of Chinese Medicine; 2020. p. 65. Chinese."},{"key":"ref41","unstructured":"Huang SH. [Clinical study of the effect of Lingnan Traditional Tianjiu prescription No.4 intervention Subthreshold depression indifferent country] [master\u2019s thesis]. [Guangzhou]: Guangzhou University of Chinese Medicine; 2022. p. 71. 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