{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T15:03:44Z","timestamp":1787670224715,"version":"build-2736575974"},"reference-count":38,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2010,5,1]],"date-time":"2010-05-01T00:00:00Z","timestamp":1272672000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Antiviral Therapy"],"published-print":{"date-parts":[[2010,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Body mass index (BMI), waist circumference (WC) and neck circumference (NC) are important screening tools for sleep disordered breathing (SDB); however, the utility of anthropometry for this purpose has not been evaluated among HIV-positive patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>HIV-negative men ( n=60), HIV-positive men receiving highly active antiretroviral therapy (HIV- positive\/ HAART; n=58) and HIV-positive men not receiving HAART (HIV-positive\/no HAART; n=41) from the Multicenter AIDS Cohort Study underwent a nocturnal sleep study and anthropomorphic assessment. Moderate-severe SDB was defined as an apnea\/hypopnea event rate \u226515 episodes\/h. Receiver operating characteristic (ROC) curves were used to compare the ability of different anthropometric measurements to predict SDB within each group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Moderate-severe SDB was found in 48% of men (HIV-negative [57%], HIV-positive\/HAART [41%] and HIV-positive\/no HAART [44%]). The performance of BMI, WC and NC to predict SDB was excellent among the HIV-negative men (ROC areas under the curve [AUCs] 0.83, 0.88 and 0.88, respectively) and fair among the HIV-positive\/HAART group (AUC 0.71, 0.77 and 0.77, respectively). By contrast, these measurements had no predictive value in the HIV-positive\/no HAART group (AUC 0.43, 0.41 and 0.45, respectively). Moreover, in the HIV-positive\/no HAART group, moderate-severe SDB was independently associated with serum C- reactive protein \u22653.0 mg\/l (odds ratio 6.9; P=0.04) and HIV RNA&gt;10,000 copies\/ml (odds ratio 7.1; P=0.05).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>BMI, WC and NC had a better predictive value for moderate-severe SDB in HIV-positive men compared with HIV-negative men, and had no value among HIV-positive\/no HAART men. Among this latter group, systemic inflammation might contribute to the pathogenesis of SDB.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3851\/imp1572","type":"journal-article","created":{"date-parts":[[2010,6,22]],"date-time":"2010-06-22T10:07:40Z","timestamp":1277201260000},"page":"651-659","source":"Crossref","is-referenced-by-count":22,"title":["Anthropometry in the prediction of sleep disordered breathing in HIV-positive and HIV-negative men"],"prefix":"10.1177","volume":"15","author":[{"given":"Todd T","family":"Brown","sequence":"first","affiliation":[{"name":"Division of Endocrinology and Metabolism, Johns Hopkins School of Medicine, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susheel P","family":"Patil","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa P","family":"Jacobson","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph B","family":"Margolick","sequence":"additional","affiliation":[{"name":"Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison M","family":"Laffan","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca J","family":"Godfrey","sequence":"additional","affiliation":[{"name":"Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacquett R","family":"Johnson","sequence":"additional","affiliation":[{"name":"Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisette M","family":"Johnson-Hill","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra M","family":"Reynolds","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan R","family":"Schwartz","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip L","family":"Smith","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2010,5,1]]},"reference":[{"key":"bibr1-IMP1572","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199304293281704"},{"key":"bibr2-IMP1572","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.165.5.2104087"},{"key":"bibr3-IMP1572","doi-asserted-by":"publisher","DOI":"10.1378\/chest.07-0040"},{"key":"bibr4-IMP1572","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000172204.82314.c3"},{"key":"bibr5-IMP1572","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-006-0241-5"},{"key":"bibr6-IMP1572","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1183\/09031936.93.03050509","volume":"3","author":"Davies R.J.","year":"1990","journal-title":"Eur Respir J"},{"key":"bibr7-IMP1572","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/18.3.158"},{"key":"bibr8-IMP1572","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0b013e318186521a"},{"key":"bibr9-IMP1572","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0b013e31815b0792"},{"key":"bibr10-IMP1572","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)11443-X"},{"key":"bibr11-IMP1572","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/126.2.310"},{"key":"bibr12-IMP1572","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-137-5_Part_2-200209031-00001"},{"key":"bibr13-IMP1572","doi-asserted-by":"publisher","DOI":"10.1086\/381684"},{"key":"bibr14-IMP1572","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/137.4.895"},{"key":"bibr15-IMP1572","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/22.5.667"},{"key":"bibr16-IMP1572","unstructured":"Westat, Inc. 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