{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T03:44:11Z","timestamp":1792035851601,"version":"4.4.0"},"reference-count":6,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Antivir Chem Chemother"],"published-print":{"date-parts":[[2011,11]]},"abstract":"<jats:p> The 24th ICAR meeting was held in Sofia, Bulgaria, 8\u201311 May 2011. This report summarizes the presentations by the ICAR award winners, Earl Kern and Brian Gowen; the keynote address by Albert (ADME) Osterhaus; the Plenary lectures by Raina Fichorova, Ralf Bartenschlager and Esteban Domingo; the invited speakers for the symposia; and a few of those by contributors. <\/jats:p><jats:p> This report aims to reflect the diversity of topics across different disciplines (chemistry to biology) discussed at ICAR: old viruses (smallpox), emerging viruses (SARS, new strains of influenza and flaviviruses), problematic viruses (HIV and HCV), sporadic viruses (arenaviruses), neglected viruses (enteroviruses), new research targets (for HCV) and new approaches (lethal mutagenesis). There were timely reports on promising compounds against adenoviruses, cytomegalovirus, HCV and HIV in clinical trials. This conference illuminated the constantly evolving field of antiviral chemotherapy by providing a forum to present and discuss new antiviral compounds, new uses for old compounds and exciting clinical results. This ICAR was a fitting testament to the \u2018father of antiviral chemotherapy\u2019, Bill Prusoff, who died aged 90 in April 2011. <\/jats:p>","DOI":"10.3851\/imp1885","type":"journal-article","created":{"date-parts":[[2011,8,12]],"date-time":"2011-08-12T13:05:39Z","timestamp":1313154339000},"page":"75-85","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Scientific Report: Highlights of 24th ICAR, 8\u201311 May 2011, Sofia, Bulgaria"],"prefix":"10.1177","volume":"22","author":[{"given":"Anthony Vere","family":"Hodge","sequence":"first","affiliation":[{"name":"Vere Hodge Antivirals Ltd, Old Denshott, Reigate, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2011,1,1]]},"reference":[{"key":"bibr1-IMP1885","doi-asserted-by":"crossref","unstructured":"Simeonova L, Gegova G, Mukova L,  Susceptibility to neuraminidase inhibitors and M2 blockers of some seasonal influenza strains isolated in Bulgaria 2004\u20132007. 24th International Conference on Antiviral Research. 8\u201311 May 2011, Sofia, Bulgaria. Abstract 83.","DOI":"10.1016\/j.antiviral.2011.03.069"},{"key":"bibr2-IMP1885","unstructured":"Richter M, Nietzsche S, Bogner E, Wutzler P, Schmidtke M. A viable human influenza A virus lacking neuramidase (NA) activity: isolation and characterisation. 24th International Conference on Antiviral Research. 8\u201311 May 2011, Sofia, Bulgaria. Abstract 106."},{"key":"bibr3-IMP1885","unstructured":"Vujo\u0161evi\u0107 D, Vuksanovic V, Poljak M, Joksimovic N. Human papillomavirus genotype distribution in women in Montenegro. 24th International Conference on Antiviral Research. 8\u201311 May 2011, Sofia, Bulgaria. Abstract 146."},{"key":"bibr4-IMP1885","doi-asserted-by":"crossref","unstructured":"Montero A, Viswanathan P, Yon C, Korba B. Nitazoxanide is an indirect inhibitor of HCV replication through modulation of cellular kinase CK1 alpha to enhance HCV NS5A hyperphosphorylation. 24th International Conference on Antiviral Research. 8\u201311 May 2011, Sofia, Bulgaria. Abstract 129.","DOI":"10.1016\/j.antiviral.2011.03.115"},{"key":"bibr5-IMP1885","unstructured":"Milani de Mayo de Mari M, Mastrangelo E, Bolognesi M,  inventors. CNR-INFM [IT], UNIV AIX Marseille II [FR]; Univ Leuven Kath [BE], assignee. Avermectins and milbemycins for the treatment of flavivirus infections. European patent EP 2327410. 2009 October 28."},{"key":"bibr6-IMP1885","unstructured":"Mastrangelo E, Pezzullo M, Bolognesi M,  Targeting the flavivirus helicase. 24th International Conference on Antiviral Research. 8\u201311 May 2011, Sofia, Bulgaria. Abstract 169."}],"container-title":["Antiviral Chemistry and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3851\/IMP1885","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.3851\/IMP1885","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3851\/IMP1885","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,4]],"date-time":"2024-09-04T13:32:12Z","timestamp":1725456732000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.3851\/IMP1885"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1,1]]},"references-count":6,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,11]]}},"alternative-id":["10.3851\/IMP1885"],"URL":"https:\/\/doi.org\/10.3851\/imp1885","relation":{},"ISSN":["0956-3202","2040-2066"],"issn-type":[{"value":"0956-3202","type":"print"},{"value":"2040-2066","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,1,1]]}}}