{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T06:03:16Z","timestamp":1791007396747,"version":"4.1.0"},"reference-count":16,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T00:00:00Z","timestamp":1417392000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Antivir Chem Chemother"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:sec><jats:title>Background:<\/jats:title><jats:p> A novel reassortant avian-origin influenza A (H7N9) virus was isolated from respiratory specimens obtained from three patients and was identified as H7N9 in China. Antiviral agents are required to treat patients with avian influenza H7N9 virus infection. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p> In this study, we assessed the antiviral potential of oseltamivir, peramivir, favipiravir (T-705), amantadine and rimantadine against novel reassortant avian-origin influenza H7N9 virus in vitro. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p> All three avian influenza H7N9 virus strains were sensitive to oseltamivir, peramivir and favipiravir (T-705), but resistant to amantadine and rimantadine. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p> Our data show a pattern of antiviral sensitivity for this novel H7N9 strain of influenza that suggests the compounds oseltamivir, peramivir and favipiravir should be useful for therapy. <\/jats:p><\/jats:sec>","DOI":"10.3851\/imp2672","type":"journal-article","created":{"date-parts":[[2013,8,15]],"date-time":"2013-08-15T16:26:51Z","timestamp":1376584011000},"page":"237-240","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":22,"title":["Inhibition of Novel Reassortant Avian Influenza H7N9 Virus Infection <i>in vitro<\/i> with Three Antiviral Drugs, Oseltamivir, Peramivir and Favipiravir"],"prefix":"10.1177","volume":"23","author":[{"given":"Rui-Yuan","family":"Cao","sequence":"first","affiliation":[{"name":"National Engineering Research Center for Strategic Drugs, Beijing Institute of Pharmacology and Toxicology, Beijing, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun-Hai","family":"Xiao","sequence":"additional","affiliation":[{"name":"National Engineering Research Center for Strategic Drugs, Beijing Institute of Pharmacology and Toxicology, Beijing, PR 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