{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T08:53:05Z","timestamp":1777452785788,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Antiviral Therapy"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:p>The authors report the difficulties of preventing mother-to-child transmission in a pregnant HIV-infected woman with a phobia of swallowing pills. After multiple attempts and just as many failures, the authors ended up with cART consisting of small tablets of nevirapine, lamivudine and a continuous intravenous infusion of zidovudine given via an elastomeric pump at home. This case demonstrates the difficulties that HIV physicians can encounter in pregnant women who have difficulties in swallowing tablets. In exceptional circumstances, continuous infusion of zidovudine may be an option, even in an outpatient setting.<\/jats:p>","DOI":"10.3851\/imp3164","type":"journal-article","created":{"date-parts":[[2017,4,3]],"date-time":"2017-04-03T05:49:26Z","timestamp":1491198566000},"page":"727-729","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Zidovudine Continuous Infusion in an HIV-Infected Pregnant Woman with a Phobia of Swallowing Pills"],"prefix":"10.1177","volume":"22","author":[{"given":"Matthijs","family":"Van Luin","sequence":"first","affiliation":[{"name":"Department of Clinical Pharmacy, Rijnstate Hospital, Arnhem, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerjanne","family":"ter Beest","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Rijnstate Hospital, Arnhem, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lia E","family":"Wijnberger","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Rijnstate Hospital, Arnhem, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline MA","family":"Swanink","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Rijnstate Hospital, Arnhem, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David M","family":"Burger","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Radboud University Medical Centre, Nijmegen, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jet H","family":"Gisolf","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Rijnstate Hospital, Arnhem, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,11,1]]},"reference":[{"key":"bibr1-IMP3164","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000000212"},{"key":"bibr2-IMP3164","unstructured":"Dutch HIV Guideline, chapter 7. [Prevention of mother to child transmission]. Dutch. (Updated 1 November 2016. Accessed 13 March 2017). Available from http:\/\/richtlijnhiv.nvhb.nl\/index.php\/Hoofdstuk_7._Preventie_van_moeder-kind_overdracht:_zwangerschap,_bevalling_en_neonatale_periode."},{"key":"bibr3-IMP3164","unstructured":"Panel on Treatment of HIV-Infected Pregnant Women and Prevention of Perinatal Transmission. Recommendations for Use of Antiretroviral Drugs in Pregnant HIV-1-Infected Women for Maternal Health and Interventions to Reduce Perinatal HIV Transmission in the United States. (Updated October 2016. Accessed 13 March 2017). Available from http:\/\/aidsinfo.nih.gov\/contentfiles\/lvguidelines\/PerinatalGL.pdf."},{"key":"bibr4-IMP3164","volume-title":"Handbook on Injectable Drugs","author":"Trissel L.A.","year":"2011","edition":"16"},{"key":"bibr5-IMP3164","unstructured":"Dutch Society for Pediatric Medicine. Updated national HIV exposition protocol for neonates. (Updated 18 December 2014. Accessed 13 March 2017). Available from http:\/\/www.nvk.nl\/tabid\/1558\/articleType\/ArticleView\/articleId\/905\/default.aspx#tab15."},{"key":"bibr6-IMP3164","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-199304000-00001"},{"key":"bibr7-IMP3164","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-110-4-279"},{"key":"bibr8-IMP3164","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198810063191401"},{"key":"bibr9-IMP3164","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchromb.2004.11.019"},{"key":"bibr10-IMP3164","unstructured":"Retrovir (zidovudine). Package insert 2016. ViiV Healthcare UK Limited, Middlesex, UK. (Accessed 13 March 2017.) Available from http:\/\/www.mhra.gov.uk\/home\/groups\/spcpil\/documents\/spcpil\/con1495172742664.pdf."}],"container-title":["Antiviral Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3851\/IMP3164","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3851\/IMP3164","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T12:52:20Z","timestamp":1777380740000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.3851\/IMP3164"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,1]]},"references-count":10,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["10.3851\/IMP3164"],"URL":"https:\/\/doi.org\/10.3851\/imp3164","relation":{},"ISSN":["1359-6535","2040-2058"],"issn-type":[{"value":"1359-6535","type":"print"},{"value":"2040-2058","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11,1]]}}}