{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T14:13:21Z","timestamp":1784038401061,"version":"3.55.0"},"reference-count":0,"publisher":"Journal of Infection in Developing Countries","issue":"08","license":[{"start":{"date-parts":[[2020,8,31]],"date-time":"2020-08-31T00:00:00Z","timestamp":1598832000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Infect Dev Ctries"],"abstract":"<jats:p>Introduction: We analyzed the clinical characteristics of COVID-19 fecal\/perianal swab nucleic acid-positive patients in our hospital and evaluated the effect of SARS-CoV-2 on the gastrointestinal tract.\r\nMethodology: Ninety-seven patients in the Fifth Affiliated Hospital of Sun Yat-sen University from January 17, 2020 to March 2, 2020 with fecal\/perianal swab samples were selected as subjects and the results of real-time fluorescence reverse transcriptase-PCR SARS-CoV-2 nucleic acid detection of fecal\/perianal swabs were used to divide subjects into positive and negative groups.\r\nResults: Fecal\/perianal swabs of 53.61% (52\/97) patients were positive including 31 males (59.62%) and 21 females (40.38%). The negative group had more females than males (P = 0.001). The distribution of case classification based on the most severe condition observed after admission was different between groups: five (5.15%) critical type patients were all from the positive group (P = 0.029). There was no statistical difference in clinical manifestations between the groups. In the positive group, the mean nucleic acid-negative conversion time was 14.13 \u00b1 8.61 days, which was significantly later than the negative group (6.98 \u00b1 5.16 days; P &lt; 0.001). In the positive group, 92% (48\/52) had nucleic acid-negative conversion with a mean nucleic acid-negative conversion time of 22.58 \u00b1 10.30 days. Among them, 41 (78.85%) cases were delayed compared with pharynx\/nasal swab nucleic acid-negative conversion time.\r\nConclusions: The positive rate of fecal\/perianal swab nucleic acid in male patients was higher than that in female patients. Fecal\/perianal swab nucleic acid positive may be an indicator of critical conditions in those with COVID-19.<\/jats:p>","DOI":"10.3855\/jidc.12885","type":"journal-article","created":{"date-parts":[[2020,9,8]],"date-time":"2020-09-08T19:34:28Z","timestamp":1599593668000},"page":"847-852","source":"Crossref","is-referenced-by-count":10,"title":["Comparison of clinical characteristics between fecal\/perianal swab nucleic acid-positive and -negative patients with COVID-19"],"prefix":"10.3855","volume":"14","author":[{"given":"Gong-Qi","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Tao","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao-Hui","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Na","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhong-Si","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin-Yu","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2222","published-online":{"date-parts":[[2020,8,31]]},"container-title":["The Journal of Infection in Developing Countries"],"original-title":[],"link":[{"URL":"https:\/\/jidc.org\/index.php\/journal\/article\/download\/12885\/2323","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jidc.org\/index.php\/journal\/article\/download\/12885\/2323","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,8]],"date-time":"2020-09-08T19:34:28Z","timestamp":1599593668000},"score":1,"resource":{"primary":{"URL":"https:\/\/jidc.org\/index.php\/journal\/article\/view\/12885"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,31]]},"references-count":0,"journal-issue":{"issue":"08","published-online":{"date-parts":[[2020,8,31]]}},"URL":"https:\/\/doi.org\/10.3855\/jidc.12885","relation":{},"ISSN":["1972-2680"],"issn-type":[{"value":"1972-2680","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,31]]}}}