{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T00:18:01Z","timestamp":1770509881032,"version":"3.49.0"},"reference-count":0,"publisher":"Journal of Infection in Developing Countries","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Infect Dev Ctries"],"abstract":"<jats:p>Introduction: Worldwide public health authorities report 500,000 cases of invasive meningococcal disease with 50,000 deaths per year and 10-15% of sequelae in people affected. This study describes the epidemiology, microbiology, and clinical presentation of this disease in the Panamanian pediatric population. Methodology: \u00a0The discharge of patients with a meningococcal invasive disease diagnosis was reviewed in the statistical database and archives of the Hospital del Ni\u00f1o. Results: A total of 32 discharges with a meningococcal disease diagnosis were reported during the study period (1998-2008).\u00a0 Ninety-one percent (n\/N = 29\/32) were confirmed as meningitis. The mean age of patients was 4.1 \u00b1 4.6 years. The incidence in the period of the study was 0.25\/100,000. Infants younger than one year old presented the highest incidence rate and number of cases. Four deaths were reported, three of which occurred in the group of 10-14 years and one in the group of 1-4 years. The overall fatality rate was 12.5%. The serogroup of the causative agent, Neisseria meningitidis, was documented in 30 of the 32 cases, with serogroup B the most frequent (66.7%). Ninety-percent (18\/20) of serogroup B were isolated in the first five years of study. Serogroup C was identified in 8 of the 12 cases during the period 2004-2008.  Conclusions: The present study showed a change in the epidemiological circulation pattern from serogroup B to serogroup C during the study period. Such epidemiological surveillance data is important in the implementation of preventive measures such as vaccination.<\/jats:p>","DOI":"10.3855\/jidc.1518","type":"journal-article","created":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T09:33:42Z","timestamp":1306920822000},"page":"318-323","source":"Crossref","is-referenced-by-count":6,"title":["Epidemiology of meningococcal disease in the Panamanian pediatric population, 1998-2008"],"prefix":"10.3855","volume":"5","author":[{"given":"Javier","family":"Nieto-Guevara","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathia","family":"Luciani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abian","family":"Montesdeoca-Mel\u00edan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mercedes","family":"Mateos-Dur\u00e1n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2222","published-online":{"date-parts":[[2010,11,22]]},"container-title":["The Journal of Infection in Developing Countries"],"original-title":[],"link":[{"URL":"https:\/\/jidc.org\/index.php\/journal\/article\/download\/21628807\/542","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jidc.org\/index.php\/journal\/article\/download\/21628807\/542","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,20]],"date-time":"2019-07-20T04:19:14Z","timestamp":1563596354000},"score":1,"resource":{"primary":{"URL":"https:\/\/jidc.org\/index.php\/journal\/article\/view\/21628807"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11,22]]},"references-count":0,"journal-issue":{"issue":"05","published-online":{"date-parts":[[2011,5,28]]}},"URL":"https:\/\/doi.org\/10.3855\/jidc.1518","relation":{},"ISSN":["1972-2680"],"issn-type":[{"value":"1972-2680","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,11,22]]}}}