{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T05:24:07Z","timestamp":1737955447439,"version":"3.33.0"},"reference-count":0,"publisher":"Journal of Infection in Developing Countries","issue":"12.1","license":[{"start":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T00:00:00Z","timestamp":1735603200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Infect Dev Ctries"],"abstract":"<jats:p>Introduction: Coronavirus disease 2019 (COVID-19) is associated with long-term symptoms, but the spectrum of these symptoms remains unclear. We aimed to identify the prevalence and factors associated with persistent symptoms in patients at the post-COVID-19 outpatient clinic.\nMethodology: This cross-sectional, observational study included hospitalized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected patients followed-up at a post-COVID-19 clinic between September 2021 and January 2022. Persistent symptoms, defined as lasting &gt; 4 weeks after infection, were analyzed alongside symptom timing (28\u201390, 91\u2013120, and &gt; 120 days) and associated factors using multivariate analysis.\nResults: Among 277 patients, mean (SD) age was 56 (16.6) years, and 58.5% were male. Of these, 80.9% reported at least one persistent symptom. Common symptoms included dyspnea (48.2%), insomnia (42.4%), and myalgia (42.1%). In multivariate analysis, being female [odds ratio (OR) 3.41; 95% confidence interval (CI) 1.5\u20137.76], and oxygen therapy (OR 3.39; 95% CI 1.3\u20138.81) were independently associated factors with persistent symptoms. High-sensitivity C-reactive protein (HsCRP) (&gt; 75 mg\/dL) was an independent risk factor for dyspnea (adjusted OR 2.29; 95% CI 1.28\u20134.12), and fatigue (adjusted OR 2.24; 95% CI 1.25\u20134). Oxygen therapy was an independent risk factor for neurologic symptoms, i.e. insomnia (adjusted OR 2.05; 95% CI 1.15\u20133.65), and brain fog (adjusted OR 2.02; 95% CI 1.14\u20133.58).\nConclusions: There was a high prevalence of persistent COVID-19 symptoms. The most common symptom was dyspnea. Female gender and oxygen supplementation were independent associated factors. Continuous follow-up of these patients is still required.<\/jats:p>","DOI":"10.3855\/jidc.19332","type":"journal-article","created":{"date-parts":[[2025,1,26]],"date-time":"2025-01-26T09:15:26Z","timestamp":1737882926000},"page":"S318-S325","source":"Crossref","is-referenced-by-count":0,"title":["Persistent COVID-19 symptoms and associated factors in a tertiary hospital in Thailand"],"prefix":"10.3855","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9309-1284","authenticated-orcid":false,"given":"Dujrath","family":"Somboonviboon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9779-0343","authenticated-orcid":false,"given":"Pattanapol","family":"Aramareerak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amornchai","family":"Lertamornpong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-8944-2986","authenticated-orcid":false,"given":"Kunchit","family":"Piyavechviratana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0181-5394","authenticated-orcid":false,"given":"Pattarin","family":"Pirompanich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2222","published-online":{"date-parts":[[2024,12,31]]},"container-title":["The Journal of Infection in Developing Countries"],"original-title":[],"link":[{"URL":"https:\/\/www.jidc.org\/index.php\/journal\/article\/download\/19332\/3552","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.jidc.org\/index.php\/journal\/article\/download\/19332\/3552","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,26]],"date-time":"2025-01-26T09:15:26Z","timestamp":1737882926000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jidc.org\/index.php\/journal\/article\/view\/19332"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,31]]},"references-count":0,"journal-issue":{"issue":"12.1","published-online":{"date-parts":[[2024,12,31]]}},"URL":"https:\/\/doi.org\/10.3855\/jidc.19332","relation":{},"ISSN":["1972-2680"],"issn-type":[{"value":"1972-2680","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,31]]}}}