{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T13:56:39Z","timestamp":1773410199851,"version":"3.50.1"},"reference-count":0,"publisher":"Journal of Infection in Developing Countries","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Infect Dev Ctries"],"abstract":"<jats:p>Introduction: Mexico\u00a0 was\u00a0 the\u00a0 first\u00a0 country\u00a0 to\u00a0 initiate\u00a0 massive\u00a0 vaccination\u00a0 with\u00a0\u00a0 heptavalent\u00a0 pneumococcal\u00a0 conjugate\u00a0 vaccine\u00a0 (PCV-7)\u00a0 in\u00a0 children.\u00a0 There\u00a0 is\u00a0 no\u00a0 information\u00a0 regarding\u00a0 pneumococcal\u00a0 invasive\u00a0 disease\u00a0 (PID)\u00a0 in\u00a0 children\u00a0 before\u00a0 and\u00a0 after\u00a0 implementation\u00a0 of\u00a0 PCV-7\u00a0 in\u00a0 Mexico\u00a0 or elsewhere\u00a0 in\u00a0 Latin America. Methodology: During\u00a0 October\u00a0 2005 to September\u00a0 2010, active\u00a0 surveillance\u00a0 for\u00a0 pediatric\u00a0 PID\u00a0 was\u00a0 initiated\u00a0 at\u00a0 Tijuana\u00a0 General\u00a0 Hospital. Only culture-confirmed cases from sterile\u00a0 fluids\u00a0 were\u00a0 included in the study.\u00a0 Serotype identification was also performed.\u00a0 Results: Twenty-eight pediatric PID cases were confirmed. Streptococcus pneumoniae was the main\u00a0 cause\u00a0 of\u00a0 pleural\u00a0 empyema\u00a0 (n = 13). It was also the\u00a0 second most common cause\u00a0 of\u00a0 confirmed\u00a0 bacterial\u00a0 meningitis\u00a0 (n = 10),\u00a0 followed\u00a0 by\u00a0 Neisseria\u00a0 meningitidis (n = ?),\u00a0 and\u00a0 the\u00a0 only\u00a0 cause\u00a0 of\u00a0 otomastoiditis\u00a0 with\u00a0 bacterial\u00a0 isolation\u00a0 (n = 5).\u00a0 Vaccine-associated\u00a0 serotypes\u00a0 decreased\u00a0 from\u00a0 54%\u00a0 before\u00a0 PCV-7\u00a0 introduction\u00a0 to\u00a0 the\u00a0 vaccination\u00a0 schedule,\u00a0 to\u00a0 only\u00a0 5.6%\u00a0 after\u00a0 PCV-7\u00a0 implementation. Serotypes\u00a0 19A\u00a0 and\u00a0 7F\u00a0 (47%\u00a0 and\u00a0 33%\u00a0 respectively)\u00a0 were\u00a0 predominant\u00a0 following\u00a0 PCV-7\u00a0 vaccination. Conclusions: Serotype\u00a0 substitution\u00a0 in\u00a0 PID\u00a0 is\u00a0 present\u00a0 in the\u00a0 northern\u00a0 border\u00a0 of\u00a0 Mexico\u00a0 following\u00a0 PCV-7\u00a0 vaccination\u00a0 in\u00a0 children.<\/jats:p>","DOI":"10.3855\/jidc.1954","type":"journal-article","created":{"date-parts":[[2012,6,17]],"date-time":"2012-06-17T21:17:31Z","timestamp":1339967851000},"page":"516-520","source":"Crossref","is-referenced-by-count":9,"title":["Pneumococcal disease: emergence of serotypes 19A and 7F following conjugate pneumococcal vaccination in a Mexican hospital"],"prefix":"10.3855","volume":"6","author":[{"given":"Enrique","family":"Chacon-Cruz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yazbeck","family":"Velazco-Mendez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel","family":"Navarro-Alvarez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosa Maria","family":"Rivas-Landeros","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Luisa","family":"Volker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graciano","family":"Lopez-Espinoza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2222","published-online":{"date-parts":[[2011,12,1]]},"container-title":["The Journal of Infection in Developing Countries"],"original-title":[],"link":[{"URL":"https:\/\/jidc.org\/index.php\/journal\/article\/download\/22706195\/741","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jidc.org\/index.php\/journal\/article\/download\/22706195\/741","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,15]],"date-time":"2019-07-15T04:23:52Z","timestamp":1563164632000},"score":1,"resource":{"primary":{"URL":"https:\/\/jidc.org\/index.php\/journal\/article\/view\/22706195"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,12,1]]},"references-count":0,"journal-issue":{"issue":"06","published-online":{"date-parts":[[2012,6,15]]}},"URL":"https:\/\/doi.org\/10.3855\/jidc.1954","relation":{},"ISSN":["1972-2680"],"issn-type":[{"value":"1972-2680","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,12,1]]}}}