{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T20:26:55Z","timestamp":1790022415201,"version":"4.0.1"},"reference-count":0,"publisher":"Journal of Infection in Developing Countries","issue":"07","license":[{"start":{"date-parts":[[2025,7,28]],"date-time":"2025-07-28T00:00:00Z","timestamp":1753660800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Infect Dev Ctries"],"abstract":"<jats:p>Introduction: This study aimed to examine the differences between coronavirus disease 2019 (COVID-19) and non-COVID-19 patients with intensive care unit (ICU)-associated bloodstream infections (BSIs), in terms of epidemiological, clinical, microbiological, and outcome data.\nMethodology: All patients who were followed up in the ICU of a university hospital between 18 March 2020 and 18 April 2022, and who had developed ICU-acquired BSI, based on the study criteria, were selected and divided into 2 groups: COVID-19 and non-COVID-19. Descriptive statistics were used to analyze differences between the groups. Logistic regression analysis was applied to determine mortality risk factors in BSI patients.\nResults: 234 patients were treated for ICU-acquired BSI, 127 COVID-19 and 107 non-COVID-19. Respiratory sources were significantly more common in COVID-19 patients compared to non-COVID-19 patients (43.3% vs. 26%, p = &lt; 0.01). Among the causative pathogens, Acinetobacter baumannii (24.4% vs. 5.6%, p \u2264 0.01) and Gram-negative multidrug-resistant (MDR) bacteria (81.7% vs. 61.7%, p = 0.020) were detected more frequently in COVID-19 patients than in non-COVID-19 patients. The duration of antibiotic use in the hospital before BSI was longer in COVID-19 patients than in non-COVID-19 patients, and this was also associated with BSI in which Gram-negative MDR bacteria were active (p = &lt; 0.01). Survival times after BSI were shorter in COVID-19 patients than in non-COVID-19 patients (p = 0.032).\nConclusions: We demonstrated that MDR microorganisms were prevalent in COVID-19 patients with ICU-acquired BSI, and this was partly due to antibiotic use in the hospital prior to BSI.<\/jats:p>","DOI":"10.3855\/jidc.20929","type":"journal-article","created":{"date-parts":[[2025,7,28]],"date-time":"2025-07-28T16:48:21Z","timestamp":1753721301000},"page":"1015-1023","source":"Crossref","is-referenced-by-count":2,"title":["Differences between COVID-19 and non-COVID-19 patients\u2019 bloodstream infections: a single-center retrospective study"],"prefix":"10.3855","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8036-3802","authenticated-orcid":false,"given":"\u00c7a\u011fla","family":"Keskin Sar\u0131ta\u015f","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Halit","family":"\u00d6zs\u00fct","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0679-0990","authenticated-orcid":false,"given":"Aysun","family":"Benli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seniha","family":"Ba\u015faran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2222","published-online":{"date-parts":[[2025,7,28]]},"container-title":["The Journal of Infection in Developing Countries"],"original-title":[],"link":[{"URL":"https:\/\/www.jidc.org\/index.php\/journal\/article\/download\/20929\/3690","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.jidc.org\/index.php\/journal\/article\/download\/20929\/3690","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,28]],"date-time":"2025-07-28T16:48:21Z","timestamp":1753721301000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jidc.org\/index.php\/journal\/article\/view\/20929"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,28]]},"references-count":0,"journal-issue":{"issue":"07","published-online":{"date-parts":[[2025,7,28]]}},"URL":"https:\/\/doi.org\/10.3855\/jidc.20929","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-4688303\/v1","asserted-by":"object"}]},"ISSN":["1972-2680"],"issn-type":[{"value":"1972-2680","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,28]]}}}