{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T17:58:04Z","timestamp":1791568684587,"version":"4.3.4"},"reference-count":0,"publisher":"Journal of Infection in Developing Countries","issue":"09","license":[{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100031980","name":"United Nations Industrial Development Organization","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100031980","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Infect Dev Ctries"],"abstract":"<jats:p>Introduction: Implementing continuous active disinfection presents challenges as conventional cleaning methods may not fully mitigate risks. Hence, evaluating innovative technologies becomes imperative. This study assessed a nanoparticle-based surface coating containing titanium dioxide engineered into nano-molecules that is activated by normal light and provides ongoing disinfection.\nMethodology: The research took place in two intensive care units (ICUs): ICU A (coated) and ICU B (control). Data on healthcare-associated infections (HAIs) and environmental factors were collected pre- and post-coating application to gauge its impact. The change in percentage of positive swabs\/HAI cases in ICU A was compared to ICU B and statistically analyzed using a 2-sample test for equality of proportions.\nResults: ICU A witnessed a 26.5% decrease in positive environment swabs post-coating, while ICU B saw a 160.9% increase. This disparity was statistically significant (p = 0.000). Both ICUs experienced decreased ventilator associated pneumonia (VAP) cases, though central line associated-blood steam infection (CLA-BSI) and catheter associated urinary tract infection (CAUTI) cases increased in ICU A post application. Following coating, positive environmental swabs and VAP decreased by 71.8%, and 72.5%, while CLA-BSI and CAUTI increased by 198% and 43.5%.\nConclusions: The evaluation showed that the coating may serve to supplement traditional cleaning and disinfection methods. Further research into the efficacy and cost-effectiveness of such antimicrobial coating is needed for overall improvement in patient care.<\/jats:p>","DOI":"10.3855\/jidc.21290","type":"journal-article","created":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T17:47:28Z","timestamp":1791568048000},"page":"1361-1367","source":"Crossref","is-referenced-by-count":0,"title":["Utility of nano-impregnated surface coating to achieve continuous active disinfection in ICU of a tertiary trauma center"],"prefix":"10.3855","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1637-7043","authenticated-orcid":false,"given":"Sharin","family":"Varma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nirupam","family":"Madaan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Purva","family":"Mathur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aparna","family":"Ningombam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajesh","family":"Malhotra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1178-4643","authenticated-orcid":false,"given":"Ganga","family":"Prasad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2222","published-online":{"date-parts":[[2026,9,30]]},"container-title":["The Journal of Infection in Developing Countries"],"original-title":[],"link":[{"URL":"https:\/\/www.jidc.org\/index.php\/journal\/article\/download\/21290\/3966","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.jidc.org\/index.php\/journal\/article\/download\/21290\/3966","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T17:47:28Z","timestamp":1791568048000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jidc.org\/index.php\/journal\/article\/view\/21290"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,30]]},"references-count":0,"journal-issue":{"issue":"09","published-online":{"date-parts":[[2026,9,30]]}},"URL":"https:\/\/doi.org\/10.3855\/jidc.21290","relation":{},"ISSN":["1972-2680"],"issn-type":[{"value":"1972-2680","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,30]]}}}