{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T19:07:28Z","timestamp":1788894448314,"version":"build-2803163510"},"reference-count":0,"publisher":"Journal of Infection in Developing Countries","issue":"08","license":[{"start":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100020655","name":"European Health and Digital Executive Agency","doi-asserted-by":"publisher","award":["101045989"],"award-info":[{"award-number":["101045989"]}],"id":[{"id":"10.13039\/100020655","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Infect Dev Ctries"],"abstract":"<jats:p>Introduction: Mpox has shown increasing incidence and geographic spread since its first identification in the Democratic Republic of the\\001 Congo (DRC) in 1970.\nMethodology: We analyzed weekly mpox surveillance data reported from 2002-2022 in the DRC. Temporal trends were assessed using time-series decomposition to separate secular trends, seasonal patterns, and residual variation. Change-point analysis identified distinct transmission phases. Spatial trends were analyzed through thematic mapping of incidence rates across Health Zones.\\001\nResults: Between 2002 and 2022, a total of 55,072 suspected mpox cases and 1,297 deaths were reported, corresponding to an overall case fatality rate (CFR) of 2.4% and a mean CFR of 2.15% (95% CI: 1.8\u20132.5). Incidence increased progressively, with marked rises after 2010 and further intensification after 2015. Recurrent seasonal peaks were observed at the beginning of the year (February) and during mid-year (May\u2013July). Change-point analysis identified four distinct transmission phases, during which annualized incidence increased from 0.78 to 2.67 cases per 100,000 population, alongside a steady geographic expansion from 56 to 159 health zones. By the most recent phase (2018\u20132022), approximately 30% of health zones nationwide had reported mpox cases. While CFRs declined during the intermediate phases, they increased again in recent years, reaching 2.63% in Phase IV.\nConclusions: Mpox remains persistently endemic in the DRC, with progressive geographic expansion. These findings underscore the need for sustained surveillance, strengthened community engagement, and targeted prevention strategies embedded within a broader One Health framework to address zoonotic and ecological drivers of transmission.<\/jats:p>","DOI":"10.3855\/jidc.21745","type":"journal-article","created":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T18:34:31Z","timestamp":1788892471000},"page":"1225-1234","source":"Crossref","is-referenced-by-count":0,"title":["Temporal, seasonal, and spatial patterns of Mpox in the DRC, 2002\u20132022: longitudinal surveillance study"],"prefix":"10.3855","volume":"20","author":[{"given":"Dominique","family":"Muteba Bapebabo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tr\u00e9sor","family":"Zola Matuvanga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5646-1784","authenticated-orcid":false,"given":"Thierry","family":"Kalonji Mukendi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8544-7685","authenticated-orcid":false,"given":"Charlotte","family":"Jackson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron","family":"Aruna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-4602-0133","authenticated-orcid":false,"given":"Joachim","family":"Kalubi Kabi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9007-1376","authenticated-orcid":false,"given":"Vivi","family":"Maketa Tevuzula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oriol","family":"Mitja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Mulangu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Judd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Gianquito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Mitashi Mulopo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hypolite","family":"Muhindo-Mavoko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2222","published-online":{"date-parts":[[2026,8,31]]},"container-title":["The Journal of Infection in Developing Countries"],"original-title":[],"link":[{"URL":"https:\/\/www.jidc.org\/index.php\/journal\/article\/download\/21745\/3949","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.jidc.org\/index.php\/journal\/article\/download\/21745\/3949","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T18:34:32Z","timestamp":1788892472000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jidc.org\/index.php\/journal\/article\/view\/21745"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,31]]},"references-count":0,"journal-issue":{"issue":"08","published-online":{"date-parts":[[2026,8,31]]}},"URL":"https:\/\/doi.org\/10.3855\/jidc.21745","relation":{},"ISSN":["1972-2680"],"issn-type":[{"value":"1972-2680","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,31]]}}}