{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T19:07:25Z","timestamp":1788894445221,"version":"build-2803163510"},"reference-count":0,"publisher":"Journal of Infection in Developing Countries","issue":"08","license":[{"start":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Infect Dev Ctries"],"abstract":"<jats:p>Introduction: Rickettsia felis, a Gram-negative obligate intracellular prokaryotic organism, causes human infections with atypical clinical presentations, commonly including fever, fatigue, headache, and maculopapular rash.\nCase presentation: This study presents a rare case of pleural effusion (PE) associated with R. felis infection, confirmed through targeted next-generation sequencing (tNGS). The patient showed significant clinical improvement and resolution of PE following empirical moxifloxacin followed by pathogen-directed therapy with rifampicin and azithromycin, along with supportive measures for circulation and immune function.\nConclusions: This case report aims to enhance early diagnosis and therapeutic strategies for R. felis infections by sharing the diagnostic and management experience.<\/jats:p>","DOI":"10.3855\/jidc.21761","type":"journal-article","created":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T18:34:30Z","timestamp":1788892470000},"page":"1256-1259","source":"Crossref","is-referenced-by-count":0,"title":["Pleural effusion caused by Rickettsia felis infection"],"prefix":"10.3855","volume":"20","author":[{"given":"Hong","family":"Ren","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingying","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanwen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingyun","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaoyang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2222","published-online":{"date-parts":[[2026,8,31]]},"container-title":["The Journal of Infection in Developing Countries"],"original-title":[],"link":[{"URL":"https:\/\/www.jidc.org\/index.php\/journal\/article\/download\/21761\/3954","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.jidc.org\/index.php\/journal\/article\/download\/21761\/3954","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T18:34:31Z","timestamp":1788892471000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jidc.org\/index.php\/journal\/article\/view\/21761"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,31]]},"references-count":0,"journal-issue":{"issue":"08","published-online":{"date-parts":[[2026,8,31]]}},"URL":"https:\/\/doi.org\/10.3855\/jidc.21761","relation":{},"ISSN":["1972-2680"],"issn-type":[{"value":"1972-2680","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,31]]}}}