{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T17:59:34Z","timestamp":1791568774992,"version":"4.3.4"},"reference-count":0,"publisher":"Journal of Infection in Developing Countries","issue":"09","license":[{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Infect Dev Ctries"],"abstract":"<jats:p>Introduction: There is limited information on non-typhoidal Salmonella (NTS) infections among children in China. The aim of this study was to explore the clinical features, strain serotypes, and drug resistance patterns of NTS infection in children.\nMethodology: A retrospective study of children with NTS admitted to three tertiary hospitals between January 2015 and December 2024 was conducted. The clinical features and drug resistance were compared among the patients.\nResults: Out of a total of 131 patients, 94 cases (71.76%) visited the hospital between June and September, and 82 cases (62.60%) were aged 6 months to 2 years. The main clinical manifestations were fever and diarrhea, with 94 cases (71.76%) presenting high fever (&gt; 39 \u2103) and 129 cases (98.50%) experiencing diarrhea. Stool consistency was predominantly loose paste or watery. Regarding serotypes, Salmonella Typhimurium was the most common (96 cases, 73.28%), while Salmonella Dublin ranked second (12 cases, 9.16%). The study revealed an increasing resistance rate to ceftriaxone. High resistance rates (&gt; 80%) were observed for ampicillin, cefazolin, and gentamicin; whereas high sensitivity (&gt; 90%) was noted for ceftazidime, piperacillin-tazobactam, and carbapenems. The rate of sensitivity to ceftazidime was linearly correlated with age (p = 0.03).\nConclusions: NTS predominantly occurred in summer and autumn among children aged 6 months to 2 years. The clinical features were primarily fever and diarrhea. Given the rising resistance to ceftriaxone, ceftazidime may be prioritized for empirical treatment.<\/jats:p>","DOI":"10.3855\/jidc.22215","type":"journal-article","created":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T17:47:22Z","timestamp":1791568042000},"page":"1308-1314","source":"Crossref","is-referenced-by-count":0,"title":["Clinical features and drug resistance analysis of non-typhoidal Salmonella infection in children"],"prefix":"10.3855","volume":"20","author":[{"given":"Guolin","family":"Rao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changqiang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuemei","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongcai","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziyang","family":"Kuang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liqun","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2222","published-online":{"date-parts":[[2026,9,30]]},"container-title":["The Journal of Infection in Developing Countries"],"original-title":[],"link":[{"URL":"https:\/\/www.jidc.org\/index.php\/journal\/article\/download\/22215\/3960","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.jidc.org\/index.php\/journal\/article\/download\/22215\/3960","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T17:47:22Z","timestamp":1791568042000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jidc.org\/index.php\/journal\/article\/view\/22215"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,30]]},"references-count":0,"journal-issue":{"issue":"09","published-online":{"date-parts":[[2026,9,30]]}},"URL":"https:\/\/doi.org\/10.3855\/jidc.22215","relation":{},"ISSN":["1972-2680"],"issn-type":[{"value":"1972-2680","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,30]]}}}