{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T18:58:05Z","timestamp":1785610685790,"version":"3.56.0"},"reference-count":0,"publisher":"Scientific Foundation Spiroski (publications)","issue":"18","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Open Access Maced J Med Sci"],"abstract":"<jats:p>BACKGROUND: Actinic keratoses (AKs) are precancerous epidermal lesions induced by chronic exposure to ultraviolet light. Several topical and surgical treatments are available. For field cancerization, photodynamic therapy (PDT) is a very effective noninvasive treatment with excellent outcome and cosmesis. The management of treatment-associated adverse events, however, is crucial to achieve the treatment aims and to ensure patients adherence to PDT.\r\nCASE REPORT: We report on adverse events and their management related to PDT. We conducted literature research on PUBMED (R). Also, we present a case of an uncommon adverse event-PDT-induced rosacea flare-up on scalp and eyes. The patient was treated successfully by submicrobial slow-release doxycycline orally.\r\nConclusions: PDT is an excellent treatment option for multiple AKs such as in bald scalp field cancerization. The management of adverse events during and after PDT is an essential part of a successful treatment plan.<\/jats:p>","DOI":"10.3889\/oamjms.2019.536","type":"journal-article","created":{"date-parts":[[2019,8,20]],"date-time":"2019-08-20T16:44:09Z","timestamp":1566319449000},"page":"2998-3001","source":"Crossref","is-referenced-by-count":8,"title":["Rosacea Flare - Up after Photodynamic Therapy (PDT) for Field Cancerization and a Review on Adverse Events with PDT in General"],"prefix":"10.3889","volume":"7","author":[{"given":"Uwe","family":"Wollina","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alena","family":"Bitel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleksandra","family":"Vojvodic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torello","family":"Lotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"52292","published-online":{"date-parts":[[2019,8,20]]},"container-title":["Open Access Macedonian Journal of Medical Sciences"],"original-title":[],"link":[{"URL":"https:\/\/spiroski.migration.publicknowledgeproject.org\/index.php\/mjms\/article\/download\/oamjms.2019.536\/3935","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/oamjms.eu\/index.php\/mjms\/article\/download\/oamjms.2019.536\/3612","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,19]],"date-time":"2023-04-19T21:32:09Z","timestamp":1681939929000},"score":1,"resource":{"primary":{"URL":"https:\/\/spiroski.migration.publicknowledgeproject.org\/index.php\/mjms\/article\/view\/oamjms.2019.536"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,20]]},"references-count":0,"journal-issue":{"issue":"18","published-online":{"date-parts":[[2019,9,30]]}},"URL":"https:\/\/doi.org\/10.3889\/oamjms.2019.536","relation":{},"ISSN":["1857-9655"],"issn-type":[{"value":"1857-9655","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,20]]}}}