{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T15:02:10Z","timestamp":1774796530776,"version":"3.50.1"},"reference-count":0,"publisher":"Scientific Foundation Spiroski (publications)","issue":"21","license":[{"start":{"date-parts":[[2019,10,13]],"date-time":"2019-10-13T00:00:00Z","timestamp":1570924800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Open Access Maced J Med Sci"],"abstract":"<jats:p>AIM: The aim of the study was to investigate the role of umbilical cord blood lactate as early predictors of hypoxic ischemic encephalopathy in newborns with perinatal asphyxia and to evaluate their sensitivity and specificity for the early identification of hypoxic ischemic encephalopathy infants.\r\nMETHODS: We performed \u00d0\u00b0 descriptive cross section\u00d0\u00b0l study between \u00d0\u0090pril 2014 \u00d0\u00b0nd \u00d0\u0090pril 2015 \u00d0\u00b0t Hue Central Hospital, Vietn\u00d0\u00b0m. 41 \u00d0\u00b0sphyxi\u00d0\u00b0 newborns (Apgar score \u00e2\u2030\u00a4 7) were included in the study. Umbilic\u00d0\u00b0l cord blood is s\u00d0\u00b0mpled for l\u00d0\u00b0ct\u00d0\u00b0te \u00d0\u00b0n\u00d0\u00b0lysis.\r\nRESULTS: Umbilic\u00d0\u00b0l cord blood l\u00d0\u00b0ct\u00d0\u00b0te levels were signific\u00d0\u00b0ntly higher \u00d0\u00b0mong inf\u00d0\u00b0nts born with HIE (me\u00d0\u00b0n 8.72 \u00c2\u00b1 1.75, r\u00d0\u00b0nge 5.12 \u00e2\u20ac\u201c 11.96) comp\u00d0\u00b0red to th\u00d0\u00b0t with asphyxic inf\u00d0\u00b0nts without HIE (me\u00d0\u00b0n 6.86 \u00c2\u00b1 1.33, r\u00d0\u00b0nge 4.74 \u00e2\u20ac\u201c 10.30), p = 0.00. With the optim\u00d0\u00b0l cutoff point for umbilic\u00d0\u00b0l cord blood l\u00d0\u00b0ct\u00d0\u00b0te level of 8.12 mmol\/l to susspected of HIE (\u00d0\u00b0re\u00d0\u00b0 under the curve 0.799) h\u00d0\u00b0d \u00d0\u00b0 sensitivity 73.7% (95% CI: 48.8-90.9), specificity 86.4% (95% CI: 65.1-97.1).\r\nCONCLUSION: Umbilical cord blood lactate could be used as early predictors in diagnosis of hypoxic ischemic encephalopathy in newborns with asphyxia.<\/jats:p>","DOI":"10.3889\/oamjms.2019.581","type":"journal-article","created":{"date-parts":[[2019,12,15]],"date-time":"2019-12-15T18:04:22Z","timestamp":1576433062000},"page":"3564-3567","source":"Crossref","is-referenced-by-count":12,"title":["Predictions of Hypoxic-Ischemic Encephalopathy by Umbilical Cord Blood Lactate in Newborns with Birth Asphyxia"],"prefix":"10.3889","volume":"7","author":[{"given":"Ton Nu","family":"Van Anh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tran","family":"Kiem Hao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nguyen Thi","family":"Diem Chi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nguyen","family":"Huu Son","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"52292","published-online":{"date-parts":[[2019,10,13]]},"container-title":["Open Access Macedonian Journal of Medical Sciences"],"original-title":[],"link":[{"URL":"https:\/\/oamjms.eu\/index.php\/mjms\/article\/download\/oamjms.2019.581\/3989","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/oamjms.eu\/index.php\/mjms\/article\/download\/oamjms.2019.581\/4176","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,23]],"date-time":"2021-03-23T17:20:28Z","timestamp":1616520028000},"score":1,"resource":{"primary":{"URL":"https:\/\/oamjms.eu\/index.php\/mjms\/article\/view\/oamjms.2019.581"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,13]]},"references-count":0,"journal-issue":{"issue":"21","published-online":{"date-parts":[[2019,11,15]]}},"URL":"https:\/\/doi.org\/10.3889\/oamjms.2019.581","relation":{},"ISSN":["1857-9655"],"issn-type":[{"value":"1857-9655","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,13]]}}}