{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T17:35:57Z","timestamp":1787160957161,"version":"build-2736575974"},"reference-count":34,"publisher":"Spandidos Publications","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,1]]},"DOI":"10.3892\/br.2013.181","type":"journal-article","created":{"date-parts":[[2013,10,7]],"date-time":"2013-10-07T07:32:03Z","timestamp":1381131123000},"page":"105-111","source":"Crossref","is-referenced-by-count":9,"title":["Meta-analysis of associations between MDM2 SNP309 polymorphism and gastric cancer risk"],"prefix":"10.3892","volume":"2","author":[{"given":"WEIFENG","family":"CHEN","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"QIANLAN","family":"WU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HONGBO","family":"REN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2013,10,7]]},"reference":[{"key":"key20180107141845_b1-br-02-01-0105","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1158\/1055-9965.EPI-11-0213","article-title":"ABO genotype and the risk of gastric cancer, atrophic gastritis, and Helicobacter pylori infection","volume":"20","author":"Nakao","year":"2011","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"key20180107141845_b2-br-02-01-0105","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.3945\/ajcn.111.012351","article-title":"Alcohol consumption and gastric cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort","volume":"94","author":"Duell","year":"2011","journal-title":"Am J Clin Nutr"},{"key":"key20180107141845_b3-br-02-01-0105","doi-asserted-by":"crossref","first-page":"1893","DOI":"10.1158\/1055-9965.EPI-10-0437","article-title":"Global patterns of cancer incidence and mortality rates and trends","volume":"19","author":"Jemal","year":"2010","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"key20180107141845_b4-br-02-01-0105","doi-asserted-by":"crossref","first-page":"2152","DOI":"10.1021\/pr060011c","article-title":"Identification and confirmation of increased fibrinopeptide a serum protein levels in gastric cancer sera by magnet bead assisted MALDI-TOF mass spectrometry","volume":"5","author":"Ebert","year":"2006","journal-title":"J Proteome Res"},{"key":"key20180107141845_b5-br-02-01-0105","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1007\/BF01535205","article-title":"Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line","volume":"13","author":"Cahilly-Snyder","year":"1987","journal-title":"Somat Cell Mol Genet"},{"key":"key20180107141845_b6-br-02-01-0105","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1002\/j.1460-2075.1991.tb07676.x","article-title":"Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line","volume":"10","author":"Fakharzadeh","year":"1991","journal-title":"EMBO J"},{"key":"key20180107141845_b7-br-02-01-0105","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1038\/sj.onc.1201432","article-title":"Mdm2: keeping p53 under control","volume":"15","author":"Piette","year":"1997","journal-title":"Oncogene"},{"key":"key20180107141845_b8-br-02-01-0105","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1007\/s10330-012-0986-9","article-title":"Clinical significance of MDM2 as a tumor biomarker","volume":"11","author":"Chen","year":"2012","journal-title":"Chin-Ger J Clin Oncol"},{"key":"key20180107141845_b9-br-02-01-0105","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1002\/bies.950151008","article-title":"The p53-mdm2 autoregulatory feedback loop: a paradigm for the regulation of growth control by p53?","volume":"15","author":"Picksley","year":"1993","journal-title":"Bioessays"},{"key":"key20180107141845_b10-br-02-01-0105","doi-asserted-by":"crossref","first-page":"4123","DOI":"10.1158\/1078-0432.CCR-07-0609","article-title":"MDM2 SNP309 polymorphism as risk factor for susceptibility and poor prognosis in renal cell carcinoma","volume":"13","author":"Hirata","year":"2007","journal-title":"Clin Cancer Res"},{"key":"key20180107141845_b11-br-02-01-0105","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1158\/1055-9965.EPI-07-2872","article-title":"MDM2 SNP309 is associated with endometrial cancer risk","volume":"17","author":"Terry","year":"2008","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"key20180107141845_b12-br-02-01-0105","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/1471-2490-13-5","article-title":"MDM2 SNP309 promoter polymorphism and p53 mutations in urinary bladder carcinoma stage T1","volume":"13","author":"Olsson","year":"2013","journal-title":"BMC Urol"},{"key":"key20180107141845_b13-br-02-01-0105","first-page":"280","article-title":"Polymorphism of MDM2 promoter, regulated by helicobacter pylori lipopolysaccharide, is associated with both an increased susceptibility to gastric carcinoma and poor prognosis in Chinese patients","volume":"26","author":"Zhang","year":"2011","journal-title":"J Gastroenterol Hepatol"},{"key":"key20180107141845_b14-br-02-01-0105","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1111\/j.1523-5378.2009.00712.x","article-title":"Interaction of Helicobacter pylori with genetic variants in the MDM2 promoter, is associated with gastric cancer susceptibility in Chinese patients","volume":"14","author":"Wang","year":"2009","journal-title":"Helicobacter"},{"key":"key20180107141845_b15-br-02-01-0105","first-page":"256","article-title":"No association of MDM2 T309G polymorphism with susceptibility to Korean gastric cancer patients","volume":"55","author":"Cho","year":"2008","journal-title":"Neoplasma"},{"key":"key20180107141845_b16-br-02-01-0105","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1136\/bmj.316.7124.61","article-title":"Bias in location and selection of studies","volume":"316","author":"Egger","year":"1998","journal-title":"BMJ"},{"key":"key20180107141845_b17-br-02-01-0105","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1186\/1471-2407-13-126","article-title":"A functional polymorphism T309G in MDM2 gene promoter, intensified by Helicobacter pylori lipopolysaccharide, is associated with both an increased susceptibility and poor prognosis of gastric carcinoma in Chinese patients","volume":"13","author":"Pan","year":"2013","journal-title":"BMC Cancer"},{"key":"key20180107141845_b18-br-02-01-0105","unstructured":"LiZAssociation of gene polymorphisms with helicobater pylori related gastric cancer in a Chinese population(unpublished masters thesis)2011"},{"key":"key20180107141845_b19-br-02-01-0105","first-page":"3342","article-title":"Relevance of MDM2 polymorphisms with esophageal squamous cell carcinoma, gastric adenocarcinoma and double primary cancers in esophagus and stomach","volume":"39","author":"ERL","year":"2012","journal-title":"Mod Prev Med"},{"key":"key20180107141845_b20-br-02-01-0105","first-page":"1594","article-title":"Relation of MDM2 gene polymorphism and Helicobacter pylori infection to gastric cardiac carcinoma","volume":"24","author":"Er","year":"2009","journal-title":"Clin Focus"},{"key":"key20180107141845_b21-br-02-01-0105","first-page":"628","article-title":"Association of the MDM2 polymorphisms with susceptibility of esophageal squamous cell carcinoma and that of gastric cardiac adenocarcinoma","volume":"27","author":"Cao","year":"2007","journal-title":"Tumor"},{"key":"key20180107141845_b22-br-02-01-0105","doi-asserted-by":"crossref","first-page":"1996","DOI":"10.1093\/carcin\/bgm168","article-title":"Interaction of P53 Arg72Pro and MDM2 T309G polymorphisms and their associations with risk of gastric cardia cancer","volume":"28","author":"Yang","year":"2007","journal-title":"Carcinogenesis"},{"key":"key20180107141845_b23-br-02-01-0105","doi-asserted-by":"crossref","first-page":"4434","DOI":"10.1200\/JCO.2005.04.1459","article-title":"MDM2 promoter polymorphism is associated with both an increased susceptibility to gastric carcinoma and poor prognosis","volume":"24","author":"Ohmiya","year":"2006","journal-title":"J Clin Oncol"},{"key":"key20180107141845_b24-br-02-01-0105","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1002\/ijc.26430","article-title":"Carcinogenesis, prevention and early detection of gastric cancer: Where we are and where we should go","volume":"15","author":"Gonz\u00e1lez","year":"2012","journal-title":"Int J Cancer"},{"key":"key20180107141845_b25-br-02-01-0105","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1136\/jmg.2006.043539","article-title":"MDM2 SNP309 accelerates colorectal tumour formation in women","volume":"43","author":"Bond","year":"2006","journal-title":"J Med Genet"},{"key":"key20180107141845_b26-br-02-01-0105","doi-asserted-by":"crossref","first-page":"2841","DOI":"10.7314\/APJCP.2012.13.6.2841","article-title":"Association between MDM2 promoter SNP309 T\/G polymorphism and liver cancer risk - a meta-analysis","volume":"13","author":"Ma","year":"2012","journal-title":"Asian Pac J Cancer Prev"},{"key":"key20180107141845_b27-br-02-01-0105","doi-asserted-by":"crossref","first-page":"e55019","DOI":"10.1371\/journal.pone.0055019","article-title":"The MDM2 309T>G polymorphism and ovarian cancer risk: a meta-analysis of 1534 cases and 2211 controls","volume":"8","author":"Ma","year":"2013","journal-title":"PLoS One"},{"key":"key20180107141845_b28-br-02-01-0105","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1159\/000343639","article-title":"The MDM2 309 T\/G polymorphism is associated with head and neck cancer risk especially in nasopharyngeal cancer: a meta-analysis","volume":"35","author":"Zhang","year":"2012","journal-title":"Onkologie"},{"key":"key20180107141845_b29-br-02-01-0105","doi-asserted-by":"crossref","first-page":"e41546","DOI":"10.1371\/journal.pone.0041546","article-title":"Association of MDM2 SNP309 variation with lung cancer risk: evidence from 7196 cases and 8456 controls","volume":"7","author":"Zhuo","year":"2012","journal-title":"PLoS One"},{"key":"key20180107141845_b30-br-02-01-0105","first-page":"1899","article-title":"MDM2 309T>G polymorphism and risk of squamous cell carcinomas of head and neck: a meta-analysis","volume":"12","author":"Liu","year":"2011","journal-title":"Asian Pac J Cancer Prev"},{"key":"key20180107141845_b31-br-02-01-0105","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/s10549-009-0467-1","article-title":"Differential effects of MDM2 SNP309 polymorphism on breast cancer risk along with race: a meta-analysis","volume":"120","author":"Economopoulos","year":"2010","journal-title":"Breast Cancer Res Treat"},{"key":"key20180107141845_b32-br-02-01-0105","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1017\/S002966510800712X","article-title":"The Second World Cancer Research Fund\/American Institute for Cancer","volume":"67","author":"Wiseman","year":"2008","journal-title":"Proc Nutr Soc"},{"key":"key20180107141845_b33-br-02-01-0105","doi-asserted-by":"crossref","first-page":"569","DOI":"10.3892\/etm.2012.640","article-title":"MDM2 SNP309 polymorphism is associated with lung cancer risk in women: a meta-analysis using METAGEN","volume":"4","author":"He","year":"2012","journal-title":"Exp Ther Med"},{"key":"key20180107141845_b34-br-02-01-0105","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1111\/j.1440-1746.2005.03880.x","article-title":"Eradication of Helicobacter pylori reduced the immunohistochemical detection of p53 and MDM2 in gastric mucosa","volume":"20","author":"Kodama","year":"2005","journal-title":"J Gastroenterol Hepatol"}],"container-title":["Biomedical Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/spandidos-publications.com\/10.3892\/br.2013.181\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,29]],"date-time":"2019-07-29T18:36:50Z","timestamp":1564425410000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spandidos-publications.com\/10.3892\/br.2013.181"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10,7]]},"references-count":34,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2013,10,7]]},"published-print":{"date-parts":[[2014,1]]}},"alternative-id":["10.3892\/br.2013.181"],"URL":"https:\/\/doi.org\/10.3892\/br.2013.181","relation":{},"ISSN":["2049-9434","2049-9442"],"issn-type":[{"value":"2049-9434","type":"print"},{"value":"2049-9442","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10,7]]}}}