{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T14:07:47Z","timestamp":1761919667227},"reference-count":30,"publisher":"Spandidos Publications","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013]]},"DOI":"10.3892\/br.2013.59","type":"journal-article","created":{"date-parts":[[2013,1,21]],"date-time":"2013-01-21T02:58:42Z","timestamp":1358737122000},"page":"320-324","source":"Crossref","is-referenced-by-count":3,"title":["Polymorphisms of STAT4 and the risk of inflammatory bowel disease: A case-control study in Chinese Han population"],"prefix":"10.3892","volume":"1","author":[{"given":"HOUBAO","family":"ZHU","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JIANBING","family":"LIU","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"HONGXIN","family":"ZHANG","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ZHENGTING","family":"WANG","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JIE","family":"LIU","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SHUNYUAN","family":"LU","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"WANGYANG","family":"XU","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JIE","family":"ZHONG","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ZHUGANG","family":"WANG","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2013,1,21]]},"reference":[{"key":"key20180107142444_b1-br-01-02-0320","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1016\/S0140-6736(07)60750-8","article-title":"Inflammatory bowel disease: cause and immunobiology","volume":"369","author":"Baumgart","year":"2007","journal-title":"Lancet"},{"key":"key20180107142444_b2-br-01-02-0320","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.1016\/S0140-6736(07)60751-X","article-title":"Inflammatory bowel disease: clinical aspects and established and evolving therapies","volume":"369","author":"Baumgart","year":"2007","journal-title":"Lancet"},{"key":"key20180107142444_b3-br-01-02-0320","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1056\/NEJMra020831","article-title":"Inflammatory bowel disease","volume":"347","author":"Podolsky","year":"2002","journal-title":"N Engl J Med"},{"key":"key20180107142444_b4-br-01-02-0320","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1038\/nature06005","article-title":"Unravelling the pathogenesis of inflammatory bowel disease","volume":"448","author":"Xavier","year":"2007","journal-title":"Nature"},{"key":"key20180107142444_b5-br-01-02-0320","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1038\/nri2340","article-title":"The genetics and immunopathogenesis of inflammatory bowel disease","volume":"8","author":"Cho","year":"2008","journal-title":"Nat Rev Immunol"},{"key":"key20180107142444_b6-br-01-02-0320","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1146\/annurev-genom-082908-150013","article-title":"The genetics of Crohn\u2019s disease","volume":"10","author":"Van Limbergen","year":"2009","journal-title":"Annu Rev Genomics Hum Genet"},{"key":"key20180107142444_b7-br-01-02-0320","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1126\/science.1135245","article-title":"A genome-wide association study identifies IL23R as an inflammatory bowel disease gene","volume":"314","author":"Duerr","year":"2006","journal-title":"Science"},{"key":"key20180107142444_b8-br-01-02-0320","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1111\/j.1572-0241.2007.01694.x","article-title":"The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn\u2019s disease in the German population","volume":"103","author":"Glas","year":"2008","journal-title":"Am J Gastroenterol"},{"key":"key20180107142444_b9-br-01-02-0320","doi-asserted-by":"crossref","first-page":"e819","DOI":"10.1371\/journal.pone.0000819","article-title":"rs1004819 is the main disease-associated IL23R variant in German Crohn\u2019s disease patients: combined analysis of IL23R, CARD15, and OCTN1\/2 variants","volume":"2","author":"Glas","year":"2007","journal-title":"PLoS One"},{"key":"key20180107142444_b10-br-01-02-0320","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/ng1954","article-title":"A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1","volume":"39","author":"Hampe","year":"2007","journal-title":"Nat Genet"},{"key":"key20180107142444_b11-br-01-02-0320","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1038\/35079107","article-title":"Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn\u2019s disease","volume":"411","author":"Hugot","year":"2001","journal-title":"Nature"},{"key":"key20180107142444_b12-br-01-02-0320","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1038\/35079114","article-title":"A frameshift mutation in NOD2 associated with susceptibility to Crohn\u2019s disease","volume":"411","author":"Ogura","year":"2001","journal-title":"Nature"},{"key":"key20180107142444_b13-br-01-02-0320","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1038\/ng2061","article-title":"Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn\u2019s disease susceptibility","volume":"39","author":"Parkes","year":"2007","journal-title":"Nat Genet"},{"key":"key20180107142444_b14-br-01-02-0320","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1038\/ng2032","article-title":"Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis","volume":"39","author":"Rioux","year":"2007","journal-title":"Nat Genet"},{"key":"key20180107142444_b15-br-01-02-0320","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/S0955-0674(00)00199-X","article-title":"The Stat family in cytokine signaling","volume":"13","author":"Ihle","year":"2001","journal-title":"Curr Opin Cell Biol"},{"key":"key20180107142444_b16-br-01-02-0320","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1056\/NEJMoa073003","article-title":"STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus","volume":"357","author":"Remmers","year":"2007","journal-title":"N Engl J Med"},{"key":"key20180107142444_b17-br-01-02-0320","doi-asserted-by":"crossref","first-page":"2598","DOI":"10.1002\/art.23792","article-title":"Association of the STAT4 gene with increased susceptibility for some immune-mediated diseases","volume":"58","author":"Martinez","year":"2008","journal-title":"Arthritis Rheum"},{"key":"key20180107142444_b18-br-01-02-0320","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/j.humimm.2010.02.005","article-title":"STAT4 gene influences genetic predisposition to ulcerative colitis but not Crohn\u2019s disease in the Spanish population: a replication study","volume":"71","author":"Diaz-Gallo","year":"2010","journal-title":"Hum Immunol"},{"key":"key20180107142444_b19-br-01-02-0320","doi-asserted-by":"crossref","first-page":"e10373","DOI":"10.1371\/journal.pone.0010373","article-title":"Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn\u2019s disease and early disease onset","volume":"5","author":"Glas","year":"2010","journal-title":"PLoS One"},{"key":"key20180107142444_b20-br-01-02-0320","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1136\/gut.2005.082909","article-title":"The Montreal classification of inflammatory bowel disease: controversies, consensus, and implications","volume":"55","author":"Satsangi","year":"2006","journal-title":"Gut"},{"issue":"Suppl A","key":"key20180107142444_b21-br-01-02-0320","doi-asserted-by":"crossref","first-page":"S5","DOI":"10.1155\/2005\/269076","article-title":"Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of Gastroenterology","volume":"19","author":"Silverberg","year":"2005","journal-title":"Can J Gastroenterol"},{"key":"key20180107142444_b22-br-01-02-0320","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1038\/cr.2009.33","article-title":"A partition-ligation-combination-subdivision EM algorithm for haplotype inference with multiallelic markers: update of the SHEsis (http:\/\/analysis.bio-x.cn)","volume":"19","author":"Li","year":"2009","journal-title":"Cell Res"},{"key":"key20180107142444_b23-br-01-02-0320","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1038\/sj.cr.7290272","article-title":"SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci","volume":"15","author":"Shi","year":"2005","journal-title":"Cell Res"},{"key":"key20180107142444_b24-br-01-02-0320","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1007\/s11882-008-0077-8","article-title":"STAT4: genetics, mechanisms, and implications for autoimmunity","volume":"8","author":"Korman","year":"2008","journal-title":"Curr Allergy Asthma Rep"},{"key":"key20180107142444_b25-br-01-02-0320","doi-asserted-by":"crossref","first-page":"1974","DOI":"10.1002\/art.23549","article-title":"Association of STAT4 with rheumatoid arthritis: a replication study in three European populations","volume":"58","author":"Orozco","year":"2008","journal-title":"Arthritis Rheum"},{"key":"key20180107142444_b26-br-01-02-0320","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1016\/j.humimm.2009.05.008","article-title":"STAT4 gene polymorphism is associated with psoriasis in the genetically homogeneous population of Crete, Greece","volume":"70","author":"Zervou","year":"2009","journal-title":"Hum Immunol"},{"key":"key20180107142444_b27-br-01-02-0320","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.lfs.2010.02.016","article-title":"Association of signal transducer and activator of transcription 4 genetic variants with extra-intestinal manifestations in inflammatory bowel disease","volume":"86","author":"Moon","year":"2010","journal-title":"Life Sci"},{"key":"key20180107142444_b28-br-01-02-0320","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1136\/ard.2009.112284","article-title":"Variation in STAT4 is associated with systemic lupus erythematosus in a Finnish family cohort","volume":"69","author":"Hellquist","year":"2010","journal-title":"Ann Rheum Dis"},{"key":"key20180107142444_b29-br-01-02-0320","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1007\/s00296-010-1767-9","article-title":"A single-nucleotide polymorphism of the STAT4 gene is associated with systemic lupus erythematosus (SLE) in female Chinese population","volume":"32","author":"Luan","year":"2012","journal-title":"Rheumatol Int"},{"key":"key20180107142444_b30-br-01-02-0320","doi-asserted-by":"crossref","first-page":"2868","DOI":"10.1093\/hmg\/ddn184","article-title":"A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5","volume":"17","author":"Sigurdsson","year":"2008","journal-title":"Hum Mol Genet"}],"container-title":["Biomedical Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/spandidos-publications.com\/10.3892\/br.2013.59\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,1,7]],"date-time":"2018-01-07T09:44:05Z","timestamp":1515318245000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spandidos-publications.com\/10.3892\/br.2013.59"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":30,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2013,1,21]]},"published-print":{"date-parts":[[2013]]}},"alternative-id":["10.3892\/br.2013.59"],"URL":"https:\/\/doi.org\/10.3892\/br.2013.59","relation":{},"ISSN":["2049-9434","2049-9442"],"issn-type":[{"value":"2049-9434","type":"print"},{"value":"2049-9442","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}