{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T22:58:25Z","timestamp":1788476305476,"version":"build-2803163510"},"reference-count":37,"publisher":"Spandidos Publications","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biomed Rep"],"DOI":"10.3892\/br.2024.1891","type":"journal-article","created":{"date-parts":[[2024,11,15]],"date-time":"2024-11-15T11:16:38Z","timestamp":1731669398000},"source":"Crossref","is-referenced-by-count":10,"title":["Efficacy and safety of remimazolam vs. propofol for general anesthesia with tracheal intubation: Systematic review and meta\u2011analysis"],"prefix":"10.3892","volume":"22","author":[{"given":"Hong","family":"Luo","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, 363 Hospital, Wuhou, Chengdu, Sichuan 610041, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuolei","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Tianfu New District People's Hospital, Shuangliu, Chengdu, Sichuan 610200, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2024,11,15]]},"reference":[{"key":"key20241209123732_b1-BR-22-1-01891","author":"Wojciechowski"},{"key":"key20241209123732_b2-BR-22-1-01891","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1111\/j.1476-5381.2010.00891.x","article-title":"New insights into the molecular mechanisms of general anaesthetics","volume":"161","author":"Chau","year":"2010","journal-title":"Br J Pharmacol"},{"issue":"F1000","key":"key20241209123732_b3-BR-22-1-01891","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.13357.1","article-title":"Recent advances in intravenous anesthesia and anesthetics","volume":"7","author":"Mahmoud","year":"2018","journal-title":"F1000Res"},{"key":"key20241209123732_b4-BR-22-1-01891"},{"key":"key20241209123732_b5-BR-22-1-01891","doi-asserted-by":"publisher","first-page":"1539","DOI":"10.1007\/s40262-018-0672-3","article-title":"Clinical pharmacokinetics and pharmacodynamics of propofol","volume":"57","author":"Sahinovic","year":"2018","journal-title":"Clin Pharmacokinet"},{"issue":"69","key":"key20241209123732_b6-BR-22-1-01891","doi-asserted-by":"publisher","DOI":"10.1186\/s13643-021-01617-5","article-title":"Midazolam for sedation before procedures in adults and children: A systematic review update","volume":"10","author":"Conway","year":"2021","journal-title":"Syst Rev"},{"issue":"154317","key":"key20241209123732_b7-BR-22-1-01891","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2023.154317","article-title":"Etomidate as an induction agent for endotracheal intubation in critically ill patients: A meta-analysis of randomized trials","volume":"77","author":"Kotani","year":"2023","journal-title":"J Critical Care"},{"key":"key20241209123732_b8-BR-22-1-01891","doi-asserted-by":"publisher","first-page":"1040","DOI":"10.4103\/aer.AER_107_17","article-title":"Effects of dexmedetomidine on intraoperative hemodynamics and propofol requirement in patients undergoing laparoscopic cholecystectomy","volume":"11","author":"Khare","year":"2017","journal-title":"Anesth Essays Res"},{"key":"key20241209123732_b9-BR-22-1-01891","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1016\/j.gie.2018.04.2351","article-title":"A phase III study evaluating the efficacy and safety of remimazolam (CNS 7056) compared with placebo and midazolam in patients undergoing colonoscopy","volume":"88","author":"Rex","year":"2018","journal-title":"Gastrointest Endosc"},{"key":"key20241209123732_b10-BR-22-1-01891","doi-asserted-by":"publisher","first-page":"984","DOI":"10.1016\/j.gie.2015.08.062","article-title":"A phase IIb study comparing the safety and efficacy of remimazolam and midazolam in patients undergoing colonoscopy","volume":"83","author":"Pambianco","year":"2016","journal-title":"Gastrointest Endosc"},{"key":"key20241209123732_b11-BR-22-1-01891","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1213\/ANE.0000000000000548","article-title":"A phase IIa, randomized, double-blind study of remimazolam (CNS 7056) versus midazolam for sedation in upper gastrointestinal endoscopy","volume":"120","author":"Borkett","year":"2015","journal-title":"Anesth Analg"},{"key":"key20241209123732_b12-BR-22-1-01891","doi-asserted-by":"publisher","first-page":"388","DOI":"10.4103\/1658-354X.136627","article-title":". Remimazolam: The future of its sedative potential","volume":"8","author":"Goudra","year":"2014","journal-title":"Saudi J Anaesth"},{"issue":"690875","key":"key20241209123732_b13-BR-22-1-01891","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.690875","article-title":"Remimazolam: Non-clinical and clinical profile of a new sedative\/anesthetic agent","volume":"12","author":"Kilpatrick","year":"2021","journal-title":"Front Pharmacol"},{"key":"key20241209123732_b14-BR-22-1-01891","doi-asserted-by":"publisher","first-page":"3957","DOI":"10.2147\/DDDT.S384155","article-title":"Remimazolam: An updated review of a new sedative and anaesthetic","volume":"16","author":"Hu","year":"2022","journal-title":"Drug Des Devel Ther"},{"key":"key20241209123732_b15-BR-22-1-01891","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1007\/s00540-020-02788-6","article-title":"Efficacy and safety of remimazolam versus propofol for general anesthesia: A multicenter, single-blind, randomized, parallel-group, phase IIb\/III trial","volume":"34","author":"Doi","year":"2020","journal-title":"J Anesth"},{"issue":"n71","key":"key20241209123732_b16-BR-22-1-01891","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: An updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"key20241209123732_b17-BR-22-1-01891"},{"key":"key20241209123732_b18-BR-22-1-01891","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1111\/biom.12817","article-title":"Quantifying publication bias in meta-analysis","volume":"74","author":"Lin","year":"2018","journal-title":"Biometrics"},{"key":"key20241209123732_b19-BR-22-1-01891","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1002\/j.2769-2795.2021.tb00081.x","article-title":"Difference between remimazolam toluenesulfonic acid and propofol in waking quality and conscious state after general anesthesia","volume":"7","author":"Li","year":"2021","journal-title":"Ibrain"},{"issue":"311","key":"key20241209123732_b20-BR-22-1-01891","doi-asserted-by":"publisher","DOI":"10.1186\/s12871-023-02249-z","article-title":"Effects of remimazolam combined with sufentanil on hemodynamics during anesthetic induction in elderly patients with mild hypertension undergoing orthopedic surgery of the lower limbs: A randomized controlled trial","volume":"23","author":"Xu","year":"2023","journal-title":"BMC Anesthesiol"},{"issue":"153","key":"key20241209123732_b21-BR-22-1-01891","doi-asserted-by":"publisher","DOI":"10.1186\/s12871-023-02095-z","article-title":"Effect of remimazolam versus propofol for the induction of general anesthesia on cerebral blood flow and oxygen saturation in elderly patients undergoing carotid endarterectomy","volume":"23","author":"Gao","year":"2023","journal-title":"BMC Anesthesiol"},{"issue":"938940","key":"key20241209123732_b22-BR-22-1-01891","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2022.938940","article-title":"The hemodynamic stability of remimazolam compared with propofol in patients undergoing endoscopic submucosal dissection: A randomized trial","volume":"9","author":"Qiu","year":"2022","journal-title":"Front Med"},{"key":"key20241209123732_b23-BR-22-1-01891","doi-asserted-by":"publisher","first-page":"10595","DOI":"10.12998\/wjcc.v9.i34.10595","article-title":"Remimazolam benzenesulfonate anesthesia effectiveness in cardiac surgery patients under general anesthesia","volume":"9","author":"Tang","year":"2021","journal-title":"World J Clin Cases"},{"issue":"219","key":"key20241209123732_b24-BR-22-1-01891","doi-asserted-by":"publisher","DOI":"10.1186\/s12871-023-02188-9","article-title":"Post-induction hypotension with remimazolam versus propofol in patients routinely administered angiotensin axis blockades: A randomized control trial","volume":"23","author":"Song","year":"2023","journal-title":"BMC Anesthesiol"},{"issue":"110955","key":"key20241209123732_b25-BR-22-1-01891","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinane.2022.110955","article-title":"Comparison of remimazolam-based and propofol-based total intravenous anesthesia on postoperative quality of recovery: A randomized non-inferiority trial","volume":"82","author":"Choi","year":"2022","journal-title":"J Clin Anesth"},{"key":"key20241209123732_b26-BR-22-1-01891","doi-asserted-by":"publisher","first-page":"583","DOI":"10.2147\/IJGM.S345390","article-title":"Efficacy and safety of remimazolam tosilate versus propofol for general anesthesia in cirrhotic patients undergoing endoscopic variceal ligation","volume":"15","author":"Shi","year":"2022","journal-title":"Int J Gen Med"},{"issue":"1265860","key":"key20241209123732_b27-BR-22-1-01891","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2023.1265860","article-title":"Safety and efficacy of remimazolam for general anesthesia in elderly patients undergoing laparoscopic cholecystectomy: A randomized controlled trial","volume":"10","author":"So","year":"2023","journal-title":"Front Med (Lausanne)"},{"issue":"e34358","key":"key20241209123732_b28-BR-22-1-01891","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000034358","article-title":"Comparison of remimazolam and propofol induction on hemodynamic response in hypertensive patients","volume":"102","author":"Choi","year":"2023","journal-title":"Medicine (Baltimore)"},{"key":"key20241209123732_b29-BR-22-1-01891","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.23736\/S0375-9393.21.15517-8","article-title":"Safety and efficacy of remimazolam compared with propofol in induction of general anesthesia","volume":"87","author":"Dai","year":"2021","journal-title":"Minerva Anestesiol"},{"key":"key20241209123732_b30-BR-22-1-01891","doi-asserted-by":"publisher","first-page":"1996","DOI":"10.1053\/j.jvca.2023.06.027","article-title":"Propofol versus remimazolam on cognitive function, hemodynamics, and oxygenation during one-lung ventilation in older patients undergoing pulmonary lobectomy: A randomized controlled trial","volume":"37","author":"Kuang","year":"2023","journal-title":"J Cardiothorac Vasc Anesth"},{"issue":"e00851","key":"key20241209123732_b31-BR-22-1-01891","doi-asserted-by":"publisher","DOI":"10.1002\/prp2.851","article-title":"Effect of remimazolam induction on hemodynamics in patients undergoing valve replacement surgery: A randomized, double-blind, controlled trial","volume":"9","author":"Liu","year":"2021","journal-title":"Pharmacol Res Perspect"},{"key":"key20241209123732_b32-BR-22-1-01891","doi-asserted-by":"publisher","first-page":"1199","DOI":"10.2147\/DDDT.S359496","article-title":"Quality of recovery after general anesthesia with remimazolam in patients' undergoing urologic surgery: A randomized controlled trial comparing remimazolam with propofol","volume":"16","author":"Mao","year":"2022","journal-title":"Drug Des Devel Ther"},{"key":"key20241209123732_b33-BR-22-1-01891","doi-asserted-by":"publisher","first-page":"1","DOI":"10.17085\/apm.21115","article-title":"Remimazolam: Pharmacological characteristics and clinical applications in anesthesiology","volume":"17","author":"Kim","year":"2022","journal-title":"Anesth Pain Med"},{"issue":"71","key":"key20241209123732_b34-BR-22-1-01891","doi-asserted-by":"publisher","DOI":"10.1186\/s40981-021-00474-4","article-title":"Anesthetic management of super-elderly patients with remimazolam: A report of two cases","volume":"7","author":"Nakayama","year":"2021","journal-title":"JA Clin Rep"},{"issue":"5536442","key":"key20241209123732_b35-BR-22-1-01891","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/5536442","article-title":"Remimazolam anesthesia for mitraclip implantation in a patient with advanced heart failure","volume":"2021","author":"Satoh","year":"2021","journal-title":"Case Rep Anesthesiol"},{"issue":"135406","key":"key20241209123732_b36-BR-22-1-01891","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2020.135406","article-title":"Induced mRNA expression of matrix metalloproteinases Mmp-3, Mmp-12, and Mmp-13 in the infarct cerebral cortex of photothrombosis model mice","volume":"739","author":"Hohjoh","year":"2020","journal-title":"Neurosci Lett"},{"issue":"7316","key":"key20241209123732_b37-BR-22-1-01891","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12237316","article-title":"Comparison of remimazolam-flumazenil versus propofol for recovery from general anesthesia: A systematic review and meta-analysis","volume":"12","author":"Wu","year":"2020","journal-title":"J Clin Med"}],"container-title":["Biomedical Reports"],"original-title":[],"deposited":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T10:37:37Z","timestamp":1733740657000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/br.2024.1891"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,15]]},"references-count":37,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,11,15]]}},"URL":"https:\/\/doi.org\/10.3892\/br.2024.1891","relation":{},"ISSN":["2049-9434","2049-9442"],"issn-type":[{"value":"2049-9434","type":"print"},{"value":"2049-9442","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,15]]},"article-number":"13"}}