{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T14:26:32Z","timestamp":1792419992592,"version":"4.5.0"},"reference-count":76,"publisher":"Spandidos Publications","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biomed Rep"],"DOI":"10.3892\/br.2025.1949","type":"journal-article","created":{"date-parts":[[2025,2,20]],"date-time":"2025-02-20T07:21:52Z","timestamp":1740036112000},"page":"1-11","source":"Crossref","is-referenced-by-count":18,"title":["The link between sex hormones and depression over a woman's lifespan (Review)"],"prefix":"10.3892","volume":"22","author":[{"given":"Iulia-Patricea","family":"Hulub\u0103","sequence":"first","affiliation":[{"name":"Department of Neurosciences, \u2018Iuliu Ha\u021bieganu\u2019 University of Medicine and Pharmacy, Cluj\u2011Napoca 400012, Rom\u00e2nia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bianca","family":"Crecan\u2011Suciu","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, \u2018Iuliu Ha\u021bieganu\u2019 University of Medicine and Pharmacy, Cluj\u2011Napoca 400012, Rom\u00e2nia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramona","family":"P\u0103unescu","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, \u2018Iuliu Ha\u021bieganu\u2019 University of Medicine and Pharmacy, Cluj\u2011Napoca 400012, Rom\u00e2nia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioana","family":"Miclu\u021bia","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, \u2018Iuliu Ha\u021bieganu\u2019 University of Medicine and Pharmacy, Cluj\u2011Napoca 400012, Rom\u00e2nia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2025,2,20]]},"reference":[{"key":"key20250314123456_b1-BR-22-4-01949"},{"key":"key20250314123456_b2-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1016\/s0165-0327(98)00131-1","article-title":"Gender differences in the prevalence of depression: A survey in primary care","volume":"53","author":"Maier","year":"1999","journal-title":"J Affect Disord"},{"key":"key20250314123456_b3-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1017\/s003329179700593x","article-title":"Puberty and depression: The roles of age, pubertal status and pubertal timing","volume":"28","author":"Angold","year":"1998","journal-title":"Psychol Med"},{"key":"key20250314123456_b4-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1034\/j.1600-0447.2003.00204.x","article-title":"Gender differences in unipolar depression: An update of epidemiological findings and possible explanations","volume":"108","author":"Kuehner","year":"2003","journal-title":"Acta Psychiatr Scand"},{"key":"key20250314123456_b5-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"686","DOI":"10.1176\/appi.ajp.2020.19080848","article-title":"Hormonal treatments for major depressive disorder: State of the art","volume":"177","author":"Dwyer","year":"2020","journal-title":"Am J Psychiatry"},{"key":"key20250314123456_b6-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"R13","DOI":"10.1530\/JOE-16-0070","article-title":"Plasma steroid-binding proteins: Primary gatekeepers of steroid hormone action","volume":"230","author":"Hammond","year":"2016","journal-title":"J Endocrinol"},{"key":"key20250314123456_b7-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"534","DOI":"10.1177\/1073858413519865","article-title":"Estrogen receptors, the hippocampus, and memory","volume":"20","author":"Bean","year":"2014","journal-title":"Neuroscientist"},{"key":"key20250314123456_b8-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/s0301-0082(00)00025-3","article-title":"Neuroprotection by estradiol","volume":"63","author":"Garcia-Segura","year":"2001","journal-title":"Prog Neurobiol"},{"key":"key20250314123456_b9-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1023\/a:1007109222673","article-title":"Neuroprotective activities of estrogen: An update","volume":"29","author":"Behl","year":"2000","journal-title":"J Neurocytol"},{"issue":"604","key":"key20250314123456_b10-BR-22-4-01949","doi-asserted-by":"publisher","DOI":"10.3109\/00048674.2011.583218","article-title":"Oestrogen and neuroprotection","volume":"45","author":"Kulkarni","year":"2011","journal-title":"Aust NZJ Psychiatry"},{"key":"key20250314123456_b11-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/j.psyneuen.2014.07.025","article-title":"Emotional and cognitive functional imaging of estrogen and progesterone effects in the female human brain: A systematic review","volume":"50","author":"Toffoletto","year":"2014","journal-title":"Psychoneuroendocrinology"},{"issue":"100856","key":"key20250314123456_b12-BR-22-4-01949","doi-asserted-by":"publisher","DOI":"10.1016\/j.yfrne.2020.100856","article-title":"Progesterone-friend or foe?","volume":"59","author":"Sundstr\u00f6m-Poromaa","year":"2020","journal-title":"Front Neuroendocrinol"},{"key":"key20250314123456_b13-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1007\/s00213-001-0959-0","article-title":"Ovarian steroid regulation of monoamine oxidase-A and -B mRNAs in the macaque dorsal raphe and hypothalamic nuclei","volume":"160","author":"Gundlah","year":"2002","journal-title":"Psychopharmacology (Berl)"},{"key":"key20250314123456_b14-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/j.mce.2004.07.017","article-title":"Intracellular signaling involved in estrogen regulation of serotonin reuptake","volume":"226","author":"Koldzic-Zivanovic","year":"2004","journal-title":"Mol Cell Endocrinol"},{"key":"key20250314123456_b15-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"797","DOI":"10.2165\/00023210-200115100-00005","article-title":"Role of estrogen in the aetiology and treatment of mood disorders","volume":"15","author":"Halbreich","year":"2001","journal-title":"CNS Drugs"},{"key":"key20250314123456_b16-BR-22-4-01949"},{"key":"key20250314123456_b17-BR-22-4-01949"},{"key":"key20250314123456_b18-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1016\/j.bbr.2012.06.034","article-title":"A rodent model of premenstrual dysphoria: Progesterone withdrawal induces depression-like behavior that is differentially sensitive to classes of antidepressants","volume":"234","author":"Li","year":"2012","journal-title":"Behav Brain Res"},{"key":"key20250314123456_b19-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1016\/j.biopsycho.2005.02.007","article-title":"Histories of depression, allopregnanolone responses to stress, and premenstrual symptoms in women","volume":"71","author":"Klatzkin","year":"2006","journal-title":"Biol Psychol"},{"issue":"CD006586","key":"key20250314123456_b20-BR-22-4-01949","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD006586.pub4","article-title":"Oral contraceptives containing drospirenone for premenstrual syndrome","volume":"15","author":"Lopez","year":"2012","journal-title":"Cochrane Database Syst Rev"},{"key":"key20250314123456_b21-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"296","DOI":"10.3109\/13625187.2015.1016154","article-title":"Comparative analysis of the effects of nomegestrol acetate\/17 \u03b2-estradiol and drospirenone\/ethinylestradiol on premenstrual and menstrual symptoms and dysmenorrhea","volume":"20","author":"Witjes","year":"2015","journal-title":"Eur J Contracept Reprod Health Care"},{"key":"key20250314123456_b22-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"e44","DOI":"10.1097\/AOG.0000000000001106","article-title":"Committee opinion No. 642: Increasing access to contraceptive implants and intrauterine devices to reduce unintended pregnancy","volume":"126","year":"2015","journal-title":"Obstet Gynecol"},{"key":"key20250314123456_b23-BR-22-4-01949","author":"Hatcher"},{"key":"key20250314123456_b24-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"S13","DOI":"10.1080\/13625180801959931","article-title":"The effects of Implanon on menstrual bleeding patterns","volume":"13 (Suppl 1)","author":"Mansour","year":"2008","journal-title":"Eur J Contracept Reprod Health Care"},{"key":"key20250314123456_b25-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.contraception.2017.10.003","article-title":"Contraceptive method use in the United States: Trends and characteristics between. 2008, 2012 and 2014","volume":"97","author":"Kavanaugh","year":"2018","journal-title":"Contraception"},{"key":"key20250314123456_b26-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1176\/appi.ajp.2020.20020154","article-title":"Contraception for women with psychiatric disorders","volume":"178","author":"McCloskey","year":"2021","journal-title":"Am J Psychiatry"},{"key":"key20250314123456_b27-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1016\/j.contraception.2011.01.021","article-title":"Contraceptive failure in the United States","volume":"83","author":"Trussell","year":"2011","journal-title":"Contraception"},{"key":"key20250314123456_b28-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1097\/AOG.0b013e3181cb50b5","article-title":"ACOG practice bulletin No. 110: Noncontraceptive uses of hormonal contraceptives","volume":"115","year":"2010","journal-title":"Obstet Gynecol"},{"key":"key20250314123456_b29-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"75","DOI":"10.18773\/austprescr.2022.025","article-title":"Hormonal contraception and mood disorders","volume":"45","author":"Mu","year":"2022","journal-title":"Aust Prescr"},{"key":"key20250314123456_b30-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/j.tics.2016.11.005","article-title":"How oral contraceptives impact social-emotional behavior and brain functions","volume":"21","author":"Montoya","year":"2017","journal-title":"Trends Cogn Sci"},{"issue":"799470","key":"key20250314123456_b31-BR-22-4-01949","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2022.799470","article-title":"Stable anxiety and depression trajectories in late adolescence for oral contraceptive users","volume":"13","author":"Doornweerd","year":"2022","journal-title":"Front Psychiatry"},{"key":"key20250314123456_b32-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1111\/jcpp.13115","article-title":"Oral contraceptive use in adolescence predicts lasting vulnerability to depression in adulthood","volume":"61","author":"Anderl","year":"2020","journal-title":"J Child Psychol Psychiatry"},{"key":"key20250314123456_b33-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"1154","DOI":"10.1001\/jamapsychiatry.2016.2387","article-title":"Association of hormonal contraception with depression","volume":"73","author":"Skovlund","year":"2016","journal-title":"JAMA Psychiatry"},{"key":"key20250314123456_b34-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1111\/jcpp.13476","article-title":"Association between adolescent oral contraceptive use and future major depressive disorder: A prospective cohort study","volume":"63","author":"Anderl","year":"2022","journal-title":"J Child Psychol Psychiatry"},{"key":"key20250314123456_b35-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1080\/13625187.2017.1422239","article-title":"Ongoing or previous mental disorders predispose to adverse mood reporting during combined oral contraceptive use","volume":"23","author":"Bengtsdotter","year":"2018","journal-title":"Eur J Contracept Reprod Health Care"},{"issue":"e39","key":"key20250314123456_b36-BR-22-4-01949","doi-asserted-by":"publisher","DOI":"10.1017\/S2045796023000525","article-title":"Population-based cohort study of oral contraceptive use and risk of depression","volume":"32","author":"Johansson","year":"2023","journal-title":"Epidemiol Psychiatr Sci"},{"key":"key20250314123456_b37-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1016\/j.jad.2023.10.041","article-title":"Association of oral contraceptive pill use and depression among US women","volume":"344","author":"Gawronska","year":"2024","journal-title":"J Affect Disord"},{"issue":"104544","key":"key20250314123456_b38-BR-22-4-01949","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2019.104544","article-title":"Use of an estradiol-based combined oral contraceptives has no influence on attentional bias or depressive symptoms in healthy women","volume":"113","author":"Scheuringer","year":"2020","journal-title":"Psychoneuroendocrinology"},{"key":"key20250314123456_b39-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"1371","DOI":"10.1016\/j.fertnstert.2005.10.031","article-title":"Decreased neuroactive steroids induced by combined oral contraceptive pills are not associated with mood changes","volume":"85","author":"Rapkin","year":"2006","journal-title":"Fertil Steril"},{"issue":"105390","key":"key20250314123456_b40-BR-22-4-01949","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2021.105390","article-title":"Oral contraceptives, depressive and insomnia symptoms in adult women with and without depression","volume":"133","author":"Morssinkhof","year":"2021","journal-title":"Psychoneuroendocrinology"},{"key":"key20250314123456_b41-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"1710","DOI":"10.1017\/S0033291720003475","article-title":"Oral contraceptive use and risk of suicidal behavior among young women","volume":"52","author":"Edwards","year":"2022","journal-title":"Psychol Med"},{"key":"key20250314123456_b42-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1176\/appi.ajp.2017.17060616","article-title":"Association of hormonal contraception with suicide attempts and suicides","volume":"175","author":"Skovlund","year":"2018","journal-title":"Am J Psychiatry"},{"key":"key20250314123456_b43-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"830","DOI":"10.1089\/jwh.2011.3466","article-title":"Depression and treatment among U.S. pregnant and nonpregnant women of reproductive age, 2005-2009","volume":"21","author":"Ko","year":"2012","journal-title":"J Womens Health (Larchmt)"},{"key":"key20250314123456_b44-BR-22-4-01949","first-page":"e15","article-title":"Depression during pregnancy: Rates, risks and consequences-motherisk update 2008","volume":"16","author":"Marcus","year":"2009","journal-title":"Can J Clin Pharmacol"},{"key":"key20250314123456_b45-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1001\/archpsyc.65.7.805","article-title":"Psychiatric disorders in pregnant and postpartum women in the United States","volume":"65","author":"Vesga-L\u00f3pez","year":"2008","journal-title":"Arch Gen Psychiatry"},{"key":"key20250314123456_b46-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"1071","DOI":"10.1097\/01.AOG.0000183597.31630.db","article-title":"Perinatal depression: A systematic review of prevalence and incidence","volume":"106","author":"Gavin","year":"2005","journal-title":"Obstet Gynecol"},{"key":"key20250314123456_b47-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1002\/da.22597","article-title":"The risk factors for postpartum depression: A population-based study","volume":"34","author":"Silverman","year":"2017","journal-title":"Depress Anxiety"},{"key":"key20250314123456_b48-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1017\/S1092852914000480","article-title":"The role of reproductive hormones in postpartum depression","volume":"20","author":"Schiller","year":"2015","journal-title":"CNS Spectr"},{"key":"key20250314123456_b49-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/s0166-4328(01)00170-x","article-title":"Estradiol alleviates depressive-like symptoms in a novel animal model of post-partum depression","volume":"122","author":"Galea","year":"2001","journal-title":"Behav Brain Res"},{"key":"key20250314123456_b50-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1016\/j.physbeh.2004.08.033","article-title":"Ovarian hormone withdrawal-induced \u2018depression\u2019 in female rats","volume":"83","author":"Stoffel","year":"2004","journal-title":"Physiol Behav"},{"key":"key20250314123456_b51-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1016\/j.biopsych.2008.03.029","article-title":"A postpartum model in rat: Behavioral and gene expression changes induced by ovarian steroid deprivation","volume":"64","author":"Suda","year":"2008","journal-title":"Biol Psychiatry"},{"key":"key20250314123456_b52-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1177\/1534582305277152","article-title":"Effect of estrogen-serotonin interactions on mood and cognition","volume":"4","author":"Amin","year":"2005","journal-title":"Behav Cogn Neurosci Rev"},{"key":"key20250314123456_b53-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/j.physbeh.2013.06.009","article-title":"Estradiol modulates anhedonia and behavioral despair in rats and negative affect in a subgroup of women at high risk for postpartum depression","volume":"119","author":"Schiller","year":"2013","journal-title":"Physiol Behav"},{"key":"key20250314123456_b54-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"924","DOI":"10.1176\/appi.ajp.157.6.924","article-title":"Effects of gonadal steroids in women with a history of postpartum depression","volume":"157","author":"Bloch","year":"2000","journal-title":"Am J Psychiatry"},{"key":"key20250314123456_b55-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1016\/j.jad.2022.06.078","article-title":"Effects of gonadal steroids on reward circuitry function and anhedonia in women with a history of postpartum depression","volume":"314","author":"Schiller","year":"2022","journal-title":"J Affect Disord"},{"key":"key20250314123456_b56-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"2309","DOI":"10.1017\/S0033291713003231","article-title":"Early predictive biomarkers for postpartum depression point to a role for estrogen receptor signaling","volume":"44","author":"Mehta","year":"2014","journal-title":"Psychol Med"},{"key":"key20250314123456_b57-BR-22-4-01949","author":"M\u00f6hler"},{"key":"key20250314123456_b58-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1016\/j.ogc.2020.05.001","article-title":"Postpartum depression: Identification and treatment in the clinic setting","volume":"47","author":"Kroska","year":"2020","journal-title":"Obstet Gynecol Clin North Am"},{"key":"key20250314123456_b59-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1007\/s00737-019-00991-3","article-title":"Transdermal estradiol for postpartum depression: Results from a pilot randomized, double-blind, placebo-controlled study","volume":"23","author":"Li","year":"2020","journal-title":"Arch Womens Ment Health"},{"key":"key20250314123456_b60-BR-22-4-01949","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1016\/S0015-0282(01)02909-0","article-title":"Executive summary: Stages of reproductive aging workshop (STRAW)","volume":"76","author":"Soules","year":"2001","journal-title":"Fertil Steril"},{"key":"key20250314123456_b61-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"S3","DOI":"10.1089\/152460900318795","article-title":"The aging ovary","volume":"9 (Suppl 1)","author":"Shifren","year":"2000","journal-title":"J Womens Health Gend Based Med"},{"key":"key20250314123456_b62-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"85","DOI":"10.2165\/00002512-200320020-00001","article-title":"Effect of reproductive hormones and selective estrogen receptor modulators on mood during menopause","volume":"20","author":"Soares","year":"2003","journal-title":"Drugs Aging"},{"key":"key20250314123456_b63-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1192\/bjp.bp.111.091751","article-title":"Oestrogen receptor polymorphisms and late-life depression","volume":"199","author":"Ryan","year":"2011","journal-title":"Br J Psychiatry"},{"key":"key20250314123456_b64-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1001\/archpsyc.61.1.62","article-title":"Hormones and menopausal status as predictors of depression in women in transition to menopause","volume":"61","author":"Freeman","year":"2004","journal-title":"Arch Gen Psychiatry"},{"key":"key20250314123456_b65-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"1879","DOI":"10.1017\/S003329171100016X","article-title":"Major depression during and after the menopausal transition: Study of women's health across the nation (SWAN)","volume":"41","author":"Bromberger","year":"2011","journal-title":"Psychol Med"},{"key":"key20250314123456_b66-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"1653","DOI":"10.1017\/S0033291714002773","article-title":"Risk factors for major depression during midlife among a community sample of women with and without prior major depression: Are they the same or different?","volume":"45","author":"Bromberger","year":"2015","journal-title":"Psychol Med"},{"key":"key20250314123456_b67-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1001\/archpsyc.63.4.375","article-title":"Associations of hormones and menopausal status with depressed mood in women with no history of depression","volume":"63","author":"Freeman","year":"2006","journal-title":"Arch Gen Psychiatry"},{"key":"key20250314123456_b68-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"823","DOI":"10.1097\/gme.0b013e3181db9f8b","article-title":"Associations of depression with the transition to menopause","volume":"17","author":"Freeman","year":"2010","journal-title":"Menopause"},{"key":"key20250314123456_b69-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1001\/jamapsychiatry.2013.2819","article-title":"Longitudinal pattern of depressive symptoms around natural menopause","volume":"71","author":"Freeman","year":"2014","journal-title":"JAMA Psychiatry"},{"key":"key20250314123456_b70-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1111\/j.1749-6632.2009.04982.x","article-title":"Sex hormones and mood in perimenopause","volume":"1179","author":"Schmidt","year":"2009","journal-title":"Ann N Y Acad Sci"},{"key":"key20250314123456_b71-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1016\/j.jad.2024.04.041","article-title":"The risk of depression in the menopausal stages: A systematic review and meta-analysis","volume":"357","author":"Badawy","year":"2024","journal-title":"J Affect Disord"},{"key":"key20250314123456_b72-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1001\/archpsyc.60.1.29","article-title":"Depression and its influence on reproductive endocrine and menstrual cycle markers associated with perimenopause: The harvard study of moods and cycles","volume":"60","author":"Harlow","year":"2003","journal-title":"Arch Gen Psychiatry"},{"key":"key20250314123456_b73-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1016\/j.biopsych.2003.08.011","article-title":"Lack of efficacy of estradiol for depression in postmenopausal women: A randomized, controlled trial","volume":"55","author":"Morrison","year":"2004","journal-title":"Biol Psychiatry"},{"key":"key20250314123456_b74-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1001\/jamapsychiatry.2017.3998","article-title":"Efficacy of transdermal estradiol and micronized progesterone in the prevention of depressive symptoms in the menopause transition: A randomized clinical trial","volume":"75","author":"Gordon","year":"2018","journal-title":"JAMA Psychiatry"},{"key":"key20250314123456_b75-BR-22-4-01949","doi-asserted-by":"publisher","first-page":"1318","DOI":"10.1097\/GME.0000000000001398","article-title":"Effects of perimenopausal transdermal estradiol on self-reported sleep, independent of its effect on vasomotor symptom bother and depressive symptoms","volume":"26","author":"Geiger","year":"2019","journal-title":"Menopause"},{"issue":"e2239491","key":"key20250314123456_b76-BR-22-4-01949","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2022.39491","article-title":"Association of hormone therapy with depression during menopause in a cohort of Danish women","volume":"5","author":"Wium-Andersen","year":"2022","journal-title":"JAMA Netw Open"}],"container-title":["Biomedical Reports"],"original-title":[],"deposited":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T10:35:03Z","timestamp":1741948503000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/br.2025.1949"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,20]]},"references-count":76,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,2,20]]}},"URL":"https:\/\/doi.org\/10.3892\/br.2025.1949","relation":{},"ISSN":["2049-9434","2049-9442"],"issn-type":[{"value":"2049-9434","type":"print"},{"value":"2049-9442","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,20]]}}}