{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T10:08:39Z","timestamp":1769508519191,"version":"3.49.0"},"reference-count":19,"publisher":"Spandidos Publications","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,9]]},"DOI":"10.3892\/etm.2015.2595","type":"journal-article","created":{"date-parts":[[2015,6,24]],"date-time":"2015-06-24T05:35:40Z","timestamp":1435124140000},"page":"1189-1193","source":"Crossref","is-referenced-by-count":17,"title":["Differences in 23S ribosomal RNA mutations between wild-type and mutant macrolide-resistant Chlamydia trachomatis isolates"],"prefix":"10.3892","volume":"10","author":[{"given":"YONG","family":"JIANG","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"HUI","family":"ZHU","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"LI-NA","family":"YANG","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"YUAN-JUN","family":"LIU","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SHU-PING","family":"HOU","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MAN-LI","family":"QI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"QUAN-ZHONG","family":"LIU","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2015,6,24]]},"reference":[{"key":"key20180108123904_b1-etm-0-0-2595","first-page":"1","article-title":"Sexually transmitted diseases treatment guidelines, 2006","volume":"55","author":"Workowski","year":"2006","journal-title":"MMWR Recomm Rep"},{"key":"key20180108123904_b2-etm-0-0-2595","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1128\/IAI.72.4.1843-1855.2004","article-title":"Chlamydial persistence: Beyond the biphasic paradigm","volume":"72","author":"Hogan","year":"2004","journal-title":"Infect Immun"},{"key":"key20180108123904_b3-etm-0-0-2595","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.micres.2005.04.004","article-title":"Chlamydia trachomatis persistence: An update","volume":"161","author":"Mpiga","year":"2006","journal-title":"Microbiol Res"},{"key":"key20180108123904_b4-etm-0-0-2595","doi-asserted-by":"crossref","first-page":"2281","DOI":"10.1517\/14656566.6.13.2281","article-title":"Therapeutic approaches to Chlamydia infections","volume":"6","author":"Senn","year":"2005","journal-title":"Expert Opin Pharmacother"},{"key":"key20180108123904_b5-etm-0-0-2595","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1086\/315372","article-title":"Multiple drug-resistant Chlamydia trachomatis associated with clinical treatment failure","volume":"181","author":"Somani","year":"2000","journal-title":"J Infect Dis"},{"key":"key20180108123904_b6-etm-0-0-2595","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1136\/sti.2005.019158","article-title":"The case for further treatment studies of uncomplicated genital Chlamydia trachomatis infection","volume":"82","author":"Horner","year":"2006","journal-title":"Sex Transm Infect"},{"key":"key20180108123904_b7-etm-0-0-2595","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0732-8893(01)00221-8","article-title":"In vitro susceptibility of recent clinical isolates of Chlamydia trachomatis to macrolides and tetracyclines","volume":"39","author":"Samra","year":"2001","journal-title":"Diagn Microbiol Infect Dis"},{"key":"key20180108123904_b8-etm-0-0-2595","doi-asserted-by":"crossref","first-page":"6571","DOI":"10.1093\/nar\/10.21.6571","article-title":"Identification of two erythromycin resistance mutations in the mitochondrial gene coding for the large ribosomal RNA in yeast","volume":"10","author":"Sor","year":"1982","journal-title":"Nucleic Acids Res"},{"key":"key20180108123904_b9-etm-0-0-2595","doi-asserted-by":"crossref","first-page":"4653","DOI":"10.1093\/nar\/12.11.4653","article-title":"Antibiotic resistance mutations in 16S and 23S ribosomal RNA genes of Escherichia coli","volume":"12","author":"Sigmund","year":"1984","journal-title":"Nucleic Acids Res"},{"key":"key20180108123904_b10-etm-0-0-2595","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1093\/infdis\/174.2.354","article-title":"Molecular mechanisms of clarithromycin resistance in Mycobacterium avium: Observation of multiple 23S rDNA mutations in a clonal population","volume":"174","author":"Meier","year":"1996","journal-title":"J Infect Dis"},{"key":"key20180108123904_b11-etm-0-0-2595","doi-asserted-by":"crossref","first-page":"2234","DOI":"10.1128\/JCM.40.6.2234-2237.2002","article-title":"Direct detection of Helicobacter pylori mutations associated with macrolide resistance in gastric biopsy material taken from human immunodeficiency virus-infected subjects","volume":"40","author":"Scarpellini","year":"2002","journal-title":"J Clin Microbiol"},{"key":"key20180108123904_b12-etm-0-0-2595","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1128\/AAC.45.1.1-12.2001","article-title":"Macrolide resistance conferred by base substitutions in 23S rRNA","volume":"45","author":"Vester","year":"2001","journal-title":"Antimicrob Agents Chemother"},{"key":"key20180108123904_b13-etm-0-0-2595","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1128\/AAC.48.4.1347-1349.2004","article-title":"Mutations in a 23S rRNA gene of Chlamydia trachomatis associated with resistance to macrolides","volume":"48","author":"Misyurina","year":"2004","journal-title":"Antimicrob Agents Chemother"},{"key":"key20180108123904_b14-etm-0-0-2595","doi-asserted-by":"crossref","first-page":"4267","DOI":"10.1128\/AAC.00962-07","article-title":"Frequency of development and associated physiological cost of azithromycin resistance in Chlamydia psittaci 6BC and C. trachomatis L2","volume":"51","author":"Binet","year":"2007","journal-title":"Antimicrob Agents Chemother"},{"key":"key20180108123904_b15-etm-0-0-2595","first-page":"282","article-title":"In vitro effects of various antibiotics alone and in combination with other antibiotics against Chlamydia trachomatis","volume":"38","author":"Shang","year":"2005","journal-title":"Chin J Dermatol"},{"key":"key20180108123904_b16-etm-0-0-2595","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1128\/AAC.36.2.291","article-title":"In vitro evaluation of activities of azithromycin, erythromycin, and tetracycline against Chlamydia trachomatis and Chlamydia pneumoniae","volume":"36","author":"Welsh","year":"1992","journal-title":"Antimicrob Agents Chemother"},{"key":"key20180108123904_b17-etm-0-0-2595","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1128\/AAC.47.2.636-642.2003","article-title":"Methodologies and cell lines used for antimicrobial susceptibility testing of Chlamydia spp","volume":"47","author":"Suchland","year":"2003","journal-title":"Antimicrob Agents Chemother"},{"key":"key20180108123904_b18-etm-0-0-2595","volume-title":"Performance Standards for Antimicrobial Susceptibility Testing; Nineteenth Informational Sulement (M100-S19)","author":"Clinical and Laboratory Standards Institute (CLSI)","year":"2009"},{"key":"key20180108123904_b19-etm-0-0-2595","doi-asserted-by":"crossref","first-page":"S105","DOI":"10.1007\/BF01793574","article-title":"In vitro stepwise selection of resistance to quinolones, beta-lactams and amikacin in nosocomial gram-negative bacilli","volume":"22","author":"Mich\u00e9a-Hamzehpour","year":"1994","journal-title":"Infection"}],"container-title":["Experimental and Therapeutic Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/spandidos-publications.com\/10.3892\/etm.2015.2595\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,1,8]],"date-time":"2018-01-08T16:53:55Z","timestamp":1515430435000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spandidos-publications.com\/10.3892\/etm.2015.2595"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6,24]]},"references-count":19,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2015,6,24]]},"published-print":{"date-parts":[[2015,9]]}},"alternative-id":["10.3892\/etm.2015.2595"],"URL":"https:\/\/doi.org\/10.3892\/etm.2015.2595","relation":{},"ISSN":["1792-0981","1792-1015"],"issn-type":[{"value":"1792-0981","type":"print"},{"value":"1792-1015","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,6,24]]}}}