{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T19:03:14Z","timestamp":1761418994963},"reference-count":19,"publisher":"Spandidos Publications","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.3892\/etm.2015.2802","type":"journal-article","created":{"date-parts":[[2015,10,15]],"date-time":"2015-10-15T08:18:39Z","timestamp":1444897119000},"page":"2029-2034","source":"Crossref","is-referenced-by-count":11,"title":["Effect of peritoneal lavage with ulinastatin on the expression of NF-\u03baB and TNF-\u03b1 in multiple organs of rats with severe acute pancreatitis"],"prefix":"10.3892","volume":"10","author":[{"given":"CONG","family":"FENG","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"BEI","family":"LI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"LI-LI","family":"WANG","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"LI","family":"CHEN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"XUAN","family":"ZHOU","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"FA-QIN","family":"LV","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"TAN-SHI","family":"LI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2015,10,15]]},"reference":[{"key":"key20180108124646_b1-etm-0-0-2802","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/BF01855643","article-title":"The effect of peritoneal lavage and aprotinin in the treatment of severe acute pancreatitis","volume":"183","author":"Balldin","year":"1983","journal-title":"Res Exp Med (Berl)"},{"key":"key20180108124646_b2-etm-0-0-2802","first-page":"2133","article-title":"Diosmetin ameliorates the severity of cerulein-induced acute pancreatitis in mice by inhibiting the activation of the nuclear factor-\u03baB","volume":"7","author":"Yu","year":"2014","journal-title":"Int J Clin Exp Pathol"},{"key":"key20180108124646_b3-etm-0-0-2802","doi-asserted-by":"crossref","first-page":"11957","DOI":"10.3390\/ijms150711957","article-title":"Catalpol ameliorates sodium taurocholate-induced acute pancreatitis in rats via inhibiting activation of nuclear factor kappa B","volume":"15","author":"Xiao","year":"2014","journal-title":"Int J Mol Sci"},{"key":"key20180108124646_b4-etm-0-0-2802","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1100\/tsw.2007.98","article-title":"TNF-alpha as a therapeutic target in acute pancreatitis - lessons from experimental models","volume":"7","author":"Malleo","year":"2007","journal-title":"ScientificWorldJournal"},{"key":"key20180108124646_b5-etm-0-0-2802","first-page":"83","article-title":"Role of the chemokine fractalkine in a rat model of acute necrotizing pancreatitis and the interventional effect of ulinastatin","volume":"16","author":"Li","year":"2013","journal-title":"Arch Iran Med"},{"key":"key20180108124646_b6-etm-0-0-2802","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1124\/mol.104.005967","article-title":"Urinary trypsin inhibitor protects against systemic inflammation induced by lipopolysaccharide","volume":"67","author":"Inoue","year":"2005","journal-title":"Mol Pharmacol"},{"key":"key20180108124646_b7-etm-0-0-2802","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.3892\/etm.2015.2334","article-title":"Ulinastatin enhances the therapeutic effect of intraperitoneal lavage on severe acute pancreatitis in rats","volume":"9","author":"Feng","year":"2015","journal-title":"Exp Ther Med"},{"key":"key20180108124646_b8-etm-0-0-2802","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1136\/gut.31.8.934","article-title":"Camostate (FOY-305) improves the therapeutic effect of peritoneal lavage on taurocholate induced pancreatitis","volume":"31","author":"Leonhardt","year":"1990","journal-title":"Gut"},{"key":"key20180108124646_b9-etm-0-0-2802","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1159\/000085265","article-title":"Pathophysiology of acute pancreatitis","volume":"5","author":"Bhatia","year":"2005","journal-title":"Pancreatology"},{"key":"key20180108124646_b10-etm-0-0-2802","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1080\/00365521.1973.12096681","article-title":"Experimental pancreatitis in the dog. Demonstration of trypsin in ascitic fluid, lymph and plasma","volume":"8","author":"Ohlsson","year":"1973","journal-title":"Scand J Gastroenterol"},{"key":"key20180108124646_b11-etm-0-0-2802","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1097\/MAJ.0b013e31827aa2bc","article-title":"The effect of somatostatin, ulinastatin and Salvia miltiorrhiza on severe acute pancreatitis treatment","volume":"346","author":"Wang","year":"2013","journal-title":"Am J Med Sci"},{"key":"key20180108124646_b12-etm-0-0-2802","doi-asserted-by":"crossref","first-page":"114","DOI":"10.2478\/pjs-2013-0020","article-title":"Morphological changes of the pancreas in course of acute pancreatitis during treatment with Ulinastatin","volume":"85","author":"Wallner","year":"2013","journal-title":"Pol Przegl Chir"},{"key":"key20180108124646_b13-etm-0-0-2802","first-page":"1229","article-title":"Continuous arterial infusion of protease inhibitor with supplementary therapy for the patients with severe acute pancreatitis - clinical effect of arterial injection of ulinastatin","volume":"95","author":"Matsukawa","year":"1998","journal-title":"Nihon Shokakibyo Gakkai Zasshi"},{"key":"key20180108124646_b14-etm-0-0-2802","doi-asserted-by":"crossref","first-page":"282645","DOI":"10.1155\/2013\/282645","article-title":"The role of IL-6, 8 and 10, sTNFr, CRP and pancreatic elastase in the prediction of systemic complications in patients with acute pancreatitis","volume":"2013","author":"Fisic","year":"2013","journal-title":"Gastroenterol Res Pract"},{"key":"key20180108124646_b15-etm-0-0-2802","doi-asserted-by":"crossref","first-page":"6273","DOI":"10.3748\/wjg.14.6273","article-title":"Prediction of severe acute pancreatitis: Current knowledge and novel insights","volume":"14","author":"Papachristou","year":"2008","journal-title":"World J Gastroenterol"},{"key":"key20180108124646_b16-etm-0-0-2802","doi-asserted-by":"crossref","first-page":"548","DOI":"10.3748\/wjg.v13.i4.548","article-title":"Influence of dexamethasone on inflammatory mediators and NF-kappaB expression in multiple organs of rats with severe acute pancreatitis","volume":"13","author":"Zhang","year":"2007","journal-title":"World J Gastroenterol"},{"key":"key20180108124646_b17-etm-0-0-2802","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1159\/000086138","article-title":"Pathophysiology of acute experimental pancreatitis: lessons from genetically engineered animal models and new molecular approaches","volume":"71","author":"Sch\u00e4fer","year":"2005","journal-title":"Digestion"},{"key":"key20180108124646_b18-etm-0-0-2802","first-page":"174","article-title":"Heat shock factor-1 and nuclear factor-kappaB are systemically activated in human acute pancreatitis","volume":"7","author":"O'Reilly","year":"2006","journal-title":"JOP"},{"key":"key20180108124646_b19-etm-0-0-2802","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1159\/000066090","article-title":"Acute experimental pancreatitis and NF-kappaB\/Rel activation","volume":"2","author":"Alg\u00fcl","year":"2002","journal-title":"Pancreatology"}],"container-title":["Experimental and Therapeutic Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/spandidos-publications.com\/10.3892\/etm.2015.2802\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,23]],"date-time":"2022-05-23T07:08:14Z","timestamp":1653289694000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spandidos-publications.com\/10.3892\/etm.2015.2802"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10,15]]},"references-count":19,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2015,10,15]]},"published-print":{"date-parts":[[2015,12]]}},"alternative-id":["10.3892\/etm.2015.2802"],"URL":"https:\/\/doi.org\/10.3892\/etm.2015.2802","relation":{},"ISSN":["1792-0981","1792-1015"],"issn-type":[{"value":"1792-0981","type":"print"},{"value":"1792-1015","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,10,15]]}}}