{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T20:33:32Z","timestamp":1792701212059,"version":"4.5.0"},"reference-count":28,"publisher":"Spandidos Publications","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,9]]},"DOI":"10.3892\/etm.2016.3552","type":"journal-article","created":{"date-parts":[[2016,7,26]],"date-time":"2016-07-26T10:16:19Z","timestamp":1469528179000},"page":"1939-1945","source":"Crossref","is-referenced-by-count":4,"title":["Similar outcomes for anti-tumor necrosis factor-\u03b1 antibody and immunosuppressant following seton drainage in patients with Crohn's disease-related anal fistula"],"prefix":"10.3892","volume":"12","author":[{"given":"Xutao","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dejun","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zerong","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Lian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaowen","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Zhi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojian","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaosheng","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Lan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2016,7,26]]},"reference":[{"key":"key20180108132339_b1-etm-0-0-3552","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1053\/gast.2002.32362","article-title":"The natural history of fistulizing Crohn's disease in Olmsted County, Minnesota","volume":"122","author":"Schwartz","year":"2002","journal-title":"Gastroenterology"},{"key":"key20180108132339_b2-etm-0-0-3552","first-page":"1503","article-title":"American Gastroenterological Association medical position statement: Perianal Crohn's disease","volume":"125","year":"2003","journal-title":"Gastroenterology"},{"key":"key20180108132339_b3-etm-0-0-3552","doi-asserted-by":"crossref","first-page":"75","DOI":"10.3748\/wjg.v12.i1.75","article-title":"Crohn's disease in Stockholm County during 1990\u20132001: An epidemiological update","volume":"12","author":"Lapidus","year":"2006","journal-title":"World J Gastroenterol"},{"key":"key20180108132339_b4-etm-0-0-3552","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1016\/j.cgh.2006.06.021","article-title":"Are perineal and luminal fistulas associated in Crohn's disease? A population-based study","volume":"4","author":"Tang","year":"2006","journal-title":"Clin Gastroenterol Hepatol"},{"key":"key20180108132339_b5-etm-0-0-3552","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1038\/ajg.2009.579","article-title":"The natural history of adult Crohn's disease in population-based cohorts","volume":"105","author":"Peyrin-Biroulet","year":"2010","journal-title":"Am J Gastroenterol"},{"key":"key20180108132339_b6-etm-0-0-3552","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1016\/j.cgh.2012.12.042","article-title":"Long-term outcome of perianal fistulizing Crohn's disease treated with infliximab","volume":"11","author":"Bouguen","year":"2013","journal-title":"Clin Gastroenterol Hepatol"},{"key":"key20180108132339_b7-etm-0-0-3552","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1007\/s10350-004-7248-z","article-title":"Endorectal advancement flap: Are there predictors of failure?","volume":"45","author":"Mizrahi","year":"2002","journal-title":"Dis Colon Rectum"},{"key":"key20180108132339_b8-etm-0-0-3552","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1007\/s10350-004-7249-y","article-title":"Outcomes of primary repair of anorectal and rectovaginal fistulas using the endorectal advancement flap","volume":"45","author":"Sonoda","year":"2002","journal-title":"Dis Colon Rectum"},{"key":"key20180108132339_b9-etm-0-0-3552","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1007\/s00384-009-0638-x","article-title":"Long-term success rate after surgical treatment of anorectal and rectovaginal fistulas in Crohn's disease","volume":"24","author":"L\u00f6ffler","year":"2009","journal-title":"Int J Colorectal Dis"},{"key":"key20180108132339_b10-etm-0-0-3552","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1007\/s10151-012-0921-7","article-title":"Video-assisted anal fistula treatment (VAAFT) combined with advancement flap repair in Crohn's disease","volume":"17","author":"Schwandner","year":"2013","journal-title":"Tech Coloproctol"},{"key":"key20180108132339_b11-etm-0-0-3552","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1016\/j.dld.2007.07.154","article-title":"The natural history of perianal Crohn's disease","volume":"39","author":"Ingle","year":"2007","journal-title":"Dig Liver Dis"},{"key":"key20180108132339_b12-etm-0-0-3552","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1007\/DCR.0b013e3182099d9e","article-title":"Quality of life in perianal Crohn's disease: What do patients consider important?","volume":"54","author":"Mahadev","year":"2011","journal-title":"Dis Colon Rectum"},{"key":"key20180108132339_b13-etm-0-0-3552","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1007\/s002680010250","article-title":"Effect of fecal diversion alone on perianal Crohn's disease","volume":"24","author":"Yamamoto","year":"2000","journal-title":"World J Surg"},{"key":"key20180108132339_b14-etm-0-0-3552","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1002\/ibd.21048","article-title":"World Gastroenterology Organization Practice Guidelines for the diagnosis and management of IBD in 2010","volume":"16","author":"Bernstein","year":"2010","journal-title":"Inflamm Bowel Dis"},{"key":"key20180108132339_b15-etm-0-0-3552","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1016\/j.gastro.2003.08.025","article-title":"American Gastroenterological Association Clinical Practice Committee: AGA technical review on perianal Crohn's disease","volume":"125","author":"Sandborn","year":"2003","journal-title":"Gastroenterology"},{"key":"key20180108132339_b16-etm-0-0-3552","first-page":"818","article-title":"The consensus on diagnosis and management of inflammatory bowel disease (Guangzhou, 2012)","volume":"2012","year":"2012","journal-title":"Zhonghua Nei Ke Za Zhi"},{"key":"key20180108132339_b17-etm-0-0-3552","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1136\/gutjnl-2013-306709","article-title":"World Gastroenterology Organization, International Organisation for Inflammatory Bowel Diseases IOIBD and European Society of Coloproctology and Robarts Clinical Trials: A global consensus on the classification, diagnosis and multidisciplinary treatment of perianal fistulising Crohn's disease","volume":"63","author":"Gecse","year":"2014","journal-title":"Gut"},{"key":"key20180108132339_b18-etm-0-0-3552","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1111\/j.1463-1318.2009.02164.x","article-title":"A meta-analysis of randomized controlled trials comparing antibacterial therapy with placebo in Crohn's disease","volume":"13","author":"Huang","year":"2011","journal-title":"Colorectal Dis"},{"key":"key20180108132339_b19-etm-0-0-3552","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1002\/ibd.20608","article-title":"Ciprofloxacin or metronidazole for the treatment of perianal fistulas in patients with Crohn's disease: A randomized, double-blind, placebo-controlled pilot study","volume":"15","author":"Thia","year":"2009","journal-title":"Inflamm Bowel Dis"},{"key":"key20180108132339_b20-etm-0-0-3552","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1136\/gutjnl-2013-304488","article-title":"Adalimumab combined with ciprofloxacin is superior to adalimumab monotherapy in perianal fistula closure in Crohn's disease: A randomised, double-blind, placebo controlled trial (ADAFI)","volume":"63","author":"Dewint","year":"2014","journal-title":"Gut"},{"key":"key20180108132339_b21-etm-0-0-3552","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1056\/NEJM199905063401804","article-title":"Infliximab for the treatment of fistulas in patients with Crohn's disease","volume":"340","author":"Present","year":"1999","journal-title":"N Engl J Med"},{"key":"key20180108132339_b22-etm-0-0-3552","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1056\/NEJMoa030815","article-title":"Infliximab maintenance therapy for fistulizing Crohn's disease","volume":"350","author":"Sands","year":"2004","journal-title":"N Engl J Med"},{"key":"key20180108132339_b23-etm-0-0-3552","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1016\/S0002-9270(02)04275-2","article-title":"Combining infliximab with 6-mercaptopurine\/azathioprine for fistula therapy in Crohn's disease","volume":"97","author":"Ochsenk\u00fchn","year":"2002","journal-title":"Am J Gastroenterol"},{"key":"key20180108132339_b24-etm-0-0-3552","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1053\/j.gastro.2005.11.030","article-title":"Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: the CLASSIC-I trial","volume":"130","author":"Hanauer","year":"2006","journal-title":"Gastroenterology"},{"key":"key20180108132339_b25-etm-0-0-3552","doi-asserted-by":"crossref","first-page":"829","DOI":"10.7326\/0003-4819-146-12-200706190-00159","article-title":"Adalimumab induction therapy for Crohn disease previously treated with infliximab: a randomized trial","volume":"146","author":"Sandborn","year":"2007","journal-title":"Ann Intern Med"},{"key":"key20180108132339_b26-etm-0-0-3552","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1111\/j.1463-1318.2012.02944.x","article-title":"Biological immunomodulators improve the healing rate in surgically treated perianal Crohn's fistulas","volume":"14","author":"El-Gazzaz","year":"2012","journal-title":"Colorectal Dis"},{"key":"key20180108132339_b27-etm-0-0-3552","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.5754\/hge09586","article-title":"Results of seton drainage and infliximab infusion for complex anal Crohn's disease","volume":"58","author":"Hotokezaka","year":"2011","journal-title":"Hepatogastroenterology"},{"key":"key20180108132339_b28-etm-0-0-3552","doi-asserted-by":"crossref","first-page":"2067","DOI":"10.1007\/s10350-007-9006-5","article-title":"Long-term quality of life in patients with Crohn's disease and perianal fistulas: Influence of fecal diversion","volume":"50","author":"Kasparek","year":"2007","journal-title":"Dis Colon Rectum"}],"container-title":["Experimental and Therapeutic Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/spandidos-publications.com\/10.3892\/etm.2016.3552\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,1,8]],"date-time":"2018-01-08T23:19:51Z","timestamp":1515453591000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spandidos-publications.com\/10.3892\/etm.2016.3552"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7,26]]},"references-count":28,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2016,7,26]]},"published-print":{"date-parts":[[2016,9]]}},"alternative-id":["10.3892\/etm.2016.3552"],"URL":"https:\/\/doi.org\/10.3892\/etm.2016.3552","relation":{},"ISSN":["1792-0981","1792-1015"],"issn-type":[{"value":"1792-0981","type":"print"},{"value":"1792-1015","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7,26]]}}}