{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T14:20:27Z","timestamp":1775830827860,"version":"3.50.1"},"reference-count":44,"publisher":"Spandidos Publications","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.3892\/etm.2016.3631","type":"journal-article","created":{"date-parts":[[2016,8,30]],"date-time":"2016-08-30T03:40:43Z","timestamp":1472528443000},"page":"2585-2593","source":"Crossref","is-referenced-by-count":4,"title":["Aminoglycoside antibiotics for NIH category II chronic bacterial prostatitis: A single-cohort study with one-year follow-up"],"prefix":"10.3892","volume":"12","author":[{"given":"Vittorio","family":"Magri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emanuele","family":"Montanari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emanuela","family":"Marras","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianpaolo","family":"Perletti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2016,8,30]]},"reference":[{"key":"key20180108132843_b1-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/S0090-4295(02)01637-0","article-title":"Epidemiologic association between prostatitis and prostate cancer","volume":"60","author":"Dennis","year":"2002","journal-title":"Urology"},{"key":"key20180108132843_b2-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1097\/01.ede.0000101022.38330.7c","article-title":"Prostatitis as a risk factor for prostate cancer","volume":"15","author":"Roberts","year":"2004","journal-title":"Epidemiology"},{"key":"key20180108132843_b3-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1038\/pcan.2015.54","article-title":"Racial differences in the relationship between clinical prostatitis, presence of inflammation in benign prostate and subsequent risk of prostate cancer","volume":"19","author":"Rybicki","year":"2016","journal-title":"Prostate Cancer Prostatic Dis"},{"key":"key20180108132843_b4-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1007\/s00345-015-1625-1","article-title":"Prostatitis, other genitourinary infections and prostate cancer: Results from a population-based case-control study","volume":"34","author":"Boehm","year":"2016","journal-title":"World J Urol"},{"key":"key20180108132843_b5-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"e85179","DOI":"10.1371\/journal.pone.0085179","article-title":"The role of prostatitis in prostate cancer: Meta-analysis","volume":"8","author":"Jiang","year":"2013","journal-title":"PLoS One"},{"key":"key20180108132843_b6-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1111\/j.1464-410X.2012.10929.x","article-title":"A case-control study of chronic prostatitis\/chronic pelvic pain syndrome and colorectal cancer","volume":"110","author":"Chung","year":"2012","journal-title":"BJU Int"},{"key":"key20180108132843_b7-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"e8736","DOI":"10.1371\/journal.pone.0008736","article-title":"Prostatitis, sexually transmitted diseases, and prostate cancer: The California Men's Health Study","volume":"5","author":"Cheng","year":"2010","journal-title":"PLoS One"},{"key":"key20180108132843_b8-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1001\/jama.282.3.236","article-title":"NIH consensus definition and classification of prostatitis","volume":"282","author":"Krieger","year":"1999","journal-title":"JAMA"},{"key":"key20180108132843_b9-etm-0-0-3631","first-page":"CD009071","article-title":"Antimicrobial therapy for chronic bacterial prostatitis","volume":"8","author":"Perletti","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"key20180108132843_b10-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/S0009-9236(03)00009-2","article-title":"Effects of three fluoroquinolones on QT interval in healthy adults after single doses","volume":"73","author":"Noel","year":"2003","journal-title":"Clin Pharmacol Ther"},{"key":"key20180108132843_b11-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1517\/14740338.2015.1085968","article-title":"Fluoroquinolone-associated tendon-rupture: A summary of reports in the Food and Drug Administration's adverse event reporting system","volume":"14","author":"Arabyat","year":"2015","journal-title":"Expert Opin Drug Saf"},{"key":"key20180108132843_b12-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"976273","DOI":"10.1155\/2012\/976273","article-title":"Global fluoroquinolone resistance epidemiology and implictions for clinical use","volume":"2012","author":"Dalhoff","year":"2012","journal-title":"Interdiscip Perspect Infect Dis"},{"key":"key20180108132843_b13-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.jhin.2015.05.006","article-title":"Effects of fluoroquinolone restriction (from 2007 to 2012) on resistance in Enterobacteriaceae: Interrupted time-series analysis","volume":"91","author":"Sarma","year":"2015","journal-title":"J Hosp Infect"},{"key":"key20180108132843_b14-etm-0-0-3631","first-page":"371","article-title":"Ciprofloxacin treatment of urinary infections results in increased resistance of urinary E. coli to ciprofloxacin and co-trimoxazole","volume":"58","author":"Borgmann","year":"2009","journal-title":"Pol J Microbiol"},{"key":"key20180108132843_b15-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/nrurol.2011.22","article-title":"The etiology and management of acute prostatitis","volume":"8","author":"Brede","year":"2011","journal-title":"Nat Rev Urol"},{"key":"key20180108132843_b16-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/1471-2334-8-12","article-title":"Acute bacterial prostatitis: Heterogeneity in diagnostic criteria and management. Retrospective multicentric analysis of 37 patients diagnosed with acute prostatitis","volume":"8","author":"Etienne","year":"2008","journal-title":"BMC Infect Dis"},{"key":"key20180108132843_b17-etm-0-0-3631","first-page":"49","article-title":"Treatment of chronic bacterial prostatitis","volume":"3","author":"Hanus","year":"1984","journal-title":"Clin Pharm"},{"key":"key20180108132843_b18-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1016\/S0140-6736(07)61602-X","article-title":"STROBE Initiative: The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: Guidelines for reporting observational studies","volume":"370","author":"von Elm","year":"2007","journal-title":"Lancet"},{"key":"key20180108132843_b19-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1038\/aja.2011.36","article-title":"Fluoroquinolone-macrolide combination therapy for chronic bacterial prostatitis: Retrospective analysis of pathogen eradication rates, inflammatory findings and sexual dysfunction","volume":"13","author":"Magri","year":"2011","journal-title":"Asian J Androl"},{"key":"key20180108132843_b20-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1177\/014107688107400106","article-title":"Prostatitis","volume":"74","author":"Stamey","year":"1981","journal-title":"J R Soc Med"},{"key":"key20180108132843_b21-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1038\/aja.2009.5","article-title":"Semen analysis in chronic bacterial prostatitis: Diagnostic and therapeutic implications","volume":"11","author":"Magri","year":"2009","journal-title":"Asian J Androl"},{"key":"key20180108132843_b22-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/j.eururo.2004.12.025","article-title":"The Italian version of the National Institutes of Health Chronic Prostatitis Symptom Index","volume":"47","author":"Giubilei","year":"2005","journal-title":"Eur Urol"},{"key":"key20180108132843_b23-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1159\/000302716","article-title":"Treatment of chronic prostatitis\/chronic pelvic pain syndrome category IIIA with Serenoa repens plus selenium and lycopene (Profluss) versus S. repens alone: An Italian randomized multicenter-controlled study","volume":"84","author":"Morgia","year":"2010","journal-title":"Urol Int"},{"key":"key20180108132843_b24-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/S0924-8579(02)00067-5","article-title":"European Lomefloxacin Prostatitis Study Group: Lomefloxacin versus ciprofloxacin in the treatment of chronic bacterial prostatitis","volume":"20","author":"Naber","year":"2002","journal-title":"Int J Antimicrob Agents"},{"key":"key20180108132843_b25-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1002\/(SICI)1096-8628(19981012)79:5<388::AID-AJMG11>3.0.CO;2-N","article-title":"Hearing loss due to the mitochondrial A1555G mutation in Italian families","volume":"79","author":"Casano","year":"1998","journal-title":"Am J Med Genet"},{"key":"key20180108132843_b26-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1007\/s100380050184","article-title":"Rapid identification of an A1555G mutation in human mitochondrial DNA implicated in aminoglycoside-induced ototoxicity","volume":"44","author":"Scrimshaw","year":"1999","journal-title":"J Hum Genet"},{"key":"key20180108132843_b27-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"175","DOI":"10.3758\/BF03193146","article-title":"G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences","volume":"39","author":"Faul","year":"2007","journal-title":"Behav Res Methods"},{"key":"key20180108132843_b28-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/S0022-5347(05)00233-8","article-title":"Chronic Prostatitis Collaborative Research Network: A prospective study of symptoms and quality of life in men with chronic prostatitis\/chronic pelvic pain syndrome: The National Institutes of Health Chronic Prostatitis Cohort study","volume":"175","author":"Propert","year":"2006","journal-title":"J Urol"},{"key":"key20180108132843_b29-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/j.eururo.2012.10.042","article-title":"National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) symptom evaluation in multinational cohorts of patients with chronic prostatitis\/chronic pelvic pain syndrome","volume":"63","author":"Wagenlehner","year":"2013","journal-title":"Eur Urol"},{"key":"key20180108132843_b30-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"2504","DOI":"10.12659\/MSM.890902","article-title":"Opening tight junctions may be key to opening the blood-prostate barrier","volume":"20","author":"Shang","year":"2014","journal-title":"Med Sci Monit"},{"key":"key20180108132843_b31-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1111\/j.1442-2042.1998.tb00597.x","article-title":"Diffusion of piperacillin, cefotiam, minocycline, amikacin and ofloxacin into the prostate","volume":"5","author":"Goto","year":"1998","journal-title":"Int J Urol"},{"issue":"Suppl 3","key":"key20180108132843_b32-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"S160","DOI":"10.1007\/BF01643689","article-title":"The treatment of chronic bacterial prostatitis","volume":"19","author":"Pfau","year":"1991","journal-title":"Infection"},{"key":"key20180108132843_b33-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1111\/j.1464-410X.1976.tb10212.x","article-title":"Chronic bacterial prostatitis: New therapeutic aspects","volume":"48","author":"Pfau","year":"1976","journal-title":"Br J Urol"},{"key":"key20180108132843_b34-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/S0090-4295(03)00565-X","article-title":"Levofloxacin versus ciprofloxacin in the treatment of chronic bacterial prostatitis: A randomized double-blind multicenter study","volume":"62","author":"Bundrick","year":"2003","journal-title":"Urology"},{"key":"key20180108132843_b35-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.ijantimicag.2006.09.027","article-title":"Efficacy of repeated cycles of combination therapy for the eradication of infecting organisms in chronic bacterial prostatitis","volume":"29","author":"Magri","year":"2007","journal-title":"Int J Antimicrob Agents"},{"key":"key20180108132843_b36-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0196-0709(97)90078-8","article-title":"Mitochondrial gene mutation is a significant predisposing factor in aminoglycoside ototoxicity","volume":"18","author":"Fischel-Ghodsian","year":"1997","journal-title":"Am J Otolaryngol"},{"key":"key20180108132843_b37-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1056\/NEJMc0806396","article-title":"Prevalence of mitochondrial 1555A\u2013\u2013>G mutation in European children","volume":"360","author":"Bitner-Glindzicz","year":"2009","journal-title":"N Engl J Med"},{"key":"key20180108132843_b38-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1056\/NEJMc0806397","article-title":"Prevalence of mitochondrial 1555A>G mutation in adults of European descent","volume":"360","author":"Vandebona","year":"2009","journal-title":"N Engl J Med"},{"key":"key20180108132843_b39-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/j.ijporl.2011.01.013","article-title":"Prevalence of A1555G mitochondrial mutation in Chinese newborns and the correlation with neonatal hearing screening","volume":"75","author":"Chen","year":"2011","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"key20180108132843_b40-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1086\/381133","article-title":"Maternally inherited aminoglycoside-induced and nonsyndromic deafness is associated with the novel C1494T mutation in the mitochondrial 12S rRNA gene in a large Chinese family","volume":"74","author":"Zhao","year":"2004","journal-title":"Am J Hum Genet"},{"key":"key20180108132843_b41-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1080\/00016480310015740","article-title":"A novel mitochondrial mutation, 1556C\u2013\u2013>T, in a Japanese patient with streptomycin-induced tinnitus","volume":"124","author":"Tanimoto","year":"2004","journal-title":"Acta Otolaryngol"},{"key":"key20180108132843_b42-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"1856","DOI":"10.1056\/NEJMc053428","article-title":"Aspirin to prevent gentamicin-induced hearing loss","volume":"354","author":"Sha","year":"2006","journal-title":"N Engl J Med"},{"key":"key20180108132843_b43-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1159\/000074526","article-title":"Penetration of antimicrobial agents into the prostate","volume":"49","author":"Charalabopoulos","year":"2003","journal-title":"Chemotherapy"},{"key":"key20180108132843_b44-etm-0-0-3631","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/j.jiac.2015.04.015","article-title":"Penetration of piperacillin-tazobactam into human prostate tissue and dosing considerations for prostatitis based on site-specific pharmacokinetics and pharmacodynamics","volume":"21","author":"Kobayashi","year":"2015","journal-title":"J Infect Chemother"}],"container-title":["Experimental and Therapeutic Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/spandidos-publications.com\/10.3892\/etm.2016.3631\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,12]],"date-time":"2019-09-12T21:58:46Z","timestamp":1568325526000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spandidos-publications.com\/10.3892\/etm.2016.3631"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,30]]},"references-count":44,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2016,8,30]]},"published-print":{"date-parts":[[2016,10]]}},"alternative-id":["10.3892\/etm.2016.3631"],"URL":"https:\/\/doi.org\/10.3892\/etm.2016.3631","relation":{},"ISSN":["1792-0981","1792-1015"],"issn-type":[{"value":"1792-0981","type":"print"},{"value":"1792-1015","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,30]]}}}