{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T05:22:38Z","timestamp":1787030558236,"version":"build-2736575974"},"reference-count":39,"publisher":"Spandidos Publications","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,4]]},"DOI":"10.3892\/etm.2017.4138","type":"journal-article","created":{"date-parts":[[2017,2,21]],"date-time":"2017-02-21T03:00:46Z","timestamp":1487646046000},"page":"1303-1312","source":"Crossref","is-referenced-by-count":7,"title":["Identification of genes associated with the effect of inflammation on the neurotransmission of vascular smooth muscle cell"],"prefix":"10.3892","volume":"13","author":[{"given":"Shujie","family":"Gan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shenlong","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiwen","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanping","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qin","family":"Qian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhong","family":"Wan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingdong","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2017,2,21]]},"reference":[{"key":"key20180108134016_b1-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1152\/physrev.1995.75.3.487","article-title":"Regulation of differentiation of vascular smooth muscle cells","volume":"75","author":"Owens","year":"1995","journal-title":"Physiol Rev"},{"key":"key20180108134016_b2-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/S0165-6147(00)01596-0","article-title":"Rho-Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cells","volume":"22","author":"Fukata","year":"2001","journal-title":"Trends Pharmacol Sci"},{"key":"key20180108134016_b3-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"2893","DOI":"10.1161\/01.CIR.0000018622.84402.FF","article-title":"Adipocyte-derived plasma protein adiponectin acts as a platelet-derived growth factor-BB-binding protein and regulates growth factor-induced common postreceptor signal in vascular smooth muscle cell","volume":"105","author":"Arita","year":"2002","journal-title":"Circulation"},{"key":"key20180108134016_b4-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.imlet.2008.07.002","article-title":"LPS induces inflammatory responses in human aortic vascular smooth muscle cells via Toll-like receptor 4 expression and nitric oxide production","volume":"120","author":"Heo","year":"2008","journal-title":"Immunol Lett"},{"key":"key20180108134016_b5-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1161\/01.RES.87.3.179","article-title":"Oxidant signaling in vascular cell growth, death, and survival a review of the roles of reactive oxygen species in smooth muscle and endothelial cell mitogenic and apoptotic signaling","volume":"87","author":"Irani","year":"2000","journal-title":"Circ Res"},{"key":"key20180108134016_b6-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1056\/NEJMra0910283","article-title":"Hypoxia and inflammation","volume":"364","author":"Eltzschig","year":"2011","journal-title":"N Engl J Med"},{"key":"key20180108134016_b7-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1023\/A:1025498319598","article-title":"Effect of propranolol on cardiac cytokine expression after myocardial infarction in rats","volume":"251","author":"Deten","year":"2003","journal-title":"Mol Cell Biochem"},{"key":"key20180108134016_b8-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"H211","DOI":"10.1152\/ajpheart.00581.2007","article-title":"Effects of isoproterenol treatment for 7 days on inflammatory mediators in the rat aorta","volume":"295","author":"Davel","year":"2008","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"key20180108134016_b9-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"647","DOI":"10.3892\/etm.2014.1780","article-title":"Effects of propranolol and isoproterenol on infantile hemangioma endothelial cells in vitro","volume":"8","author":"Zhu","year":"2014","journal-title":"Exp Ther Med"},{"key":"key20180108134016_b10-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"2455","DOI":"10.1007\/s00125-009-1509-2","article-title":"Extracellular PBEF\/NAMPT\/visfatin activates pro-inflammatory signalling in human vascular smooth muscle cells through nicotinamide phosphoribosyltransferase activity","volume":"52","author":"Romacho","year":"2009","journal-title":"Diabetologia"},{"key":"key20180108134016_b11-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1172\/JCI200112455","article-title":"The adhesion receptor CD44 promotes atherosclerosis by mediating inflammatory cell recruitment and vascular cell activation","volume":"108","author":"Cuff","year":"2001","journal-title":"J Clin Invest"},{"key":"key20180108134016_b12-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1161\/01.ATV.0000043456.48735.20","article-title":"HMG-CoA reductase inhibitors regulate inflammatory transcription factors in human endothelial and vascular smooth muscle cells","volume":"23","author":"Dichtl","year":"2003","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"key20180108134016_b13-etm-0-0-4138","doi-asserted-by":"crossref","DOI":"10.1002\/0471142727.mb0412s94","article-title":"Construction of normalized RNA-seq libraries for next-generation sequencing using the crab duplex-specific nuclease","volume":"4","author":"Christodoulou","year":"2011","journal-title":"Curr Protoc Mol Biol Chapter"},{"key":"key20180108134016_b14-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1093\/bioinformatics\/btp120","article-title":"TopHat: Discovering splice junctions with RNA-Seq","volume":"25","author":"Trapnell","year":"2009","journal-title":"Bioinformatics"},{"key":"key20180108134016_b15-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/978-1-4939-2291-8_20","article-title":"Exploring the RNA editing potential of RNA-Seq data by ExpEdit","volume":"1269","author":"D'Antonio","year":"2015","journal-title":"Methods Mol Biol"},{"key":"key20180108134016_b16-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1038\/nprot.2012.016","article-title":"Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks","volume":"7","author":"Trapnell","year":"2012","journal-title":"Nat Protoc"},{"key":"key20180108134016_b17-etm-0-0-4138","article-title":"NOISeq: Exploratory analysis and differential expression for RNA-seq data","author":"Tarazona","year":"2012","journal-title":"R package version 200"},{"key":"key20180108134016_b18-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1038\/75556","article-title":"Gene ontology: Tool for the unification of biology. The Gene Ontology Consortium","volume":"25","author":"Ashburner","year":"2000","journal-title":"Nature genetics"},{"key":"key20180108134016_b19-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1186\/1471-2164-6-60","article-title":"PathwayVoyager: Pathway mapping using the Kyoto Encyclopedia of Genes and Genomes (KEGG) database","volume":"6","author":"Altermann","year":"2005","journal-title":"BMC Genomics"},{"key":"key20180108134016_b20-etm-0-0-4138","first-page":"44","article-title":"Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources","volume":"4","author":"da","year":"2008","journal-title":"Nat Protoc"},{"key":"key20180108134016_b21-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"3442","DOI":"10.1093\/nar\/28.18.3442","article-title":"STRING: A web-server to retrieve and display the repeatedly occurring neighbourhood of a gene","volume":"28","author":"Snel","year":"2000","journal-title":"Nucleic Acids Res"},{"key":"key20180108134016_b22-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1093\/bioinformatics\/btq675","article-title":"Cytoscape 2.8: New features for data integration and network visualization","volume":"27","author":"Smoot","year":"2011","journal-title":"Bioinformatics"},{"key":"key20180108134016_b23-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1007\/BF01986693","article-title":"Calcium pyrophosphate-induced pleurisy in rats: A new model of acute inflammation. 1975","volume":"43","author":"Willoughby","year":"1994","journal-title":"Agents Actions"},{"key":"key20180108134016_b24-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1016\/j.parkreldis.2010.09.007","article-title":"Genetic variation of the mitochondrial complex I subunit NDUFV2 and Parkinson's disease","volume":"16","author":"Nishioka","year":"2010","journal-title":"Parkinsonism Relat Disord"},{"key":"key20180108134016_b25-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1002\/ajmg.b.30285","article-title":"Association of mitochondrial complex I subunit gene NDUFV2 at 18p11 with schizophrenia in the Japanese population","volume":"141B","author":"Washizuka","year":"2006","journal-title":"Am J Med Genet B Neuropsychiatr Genet"},{"key":"key20180108134016_b26-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/1423-0127-18-29","article-title":"Mitochondrial targeting of human NADH dehydrogenase (ubiquinone) flavoprotein 2 (NDUFV2) and its association with early-onset hypertrophic cardiomyopathy and encephalopathy","volume":"18","author":"Liu","year":"2011","journal-title":"J Biomed Sci"},{"key":"key20180108134016_b27-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"149","DOI":"10.4236\/nm.2014.54018","article-title":"Over-expressing prohibitin (PHB) in neuronal cultures exacerbates cell death following hydrogen peroxide and L-glutamic acid induced injury","volume":"5","author":"Teoh","year":"2014","journal-title":"Neurosci Med"},{"key":"key20180108134016_b28-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"113","DOI":"10.2220\/biomedres.31.113","article-title":"Prohibitin protects against hypoxia-induced H9c2 cardiomyocyte cell death","volume":"31","author":"Muraguchi","year":"2010","journal-title":"Biomed Res"},{"key":"key20180108134016_b29-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1002\/hep.22998","article-title":"Proteomics analysis of mitochondrial proteins reveals overexpression of a mitochondrial protein chaperon, prohibitin, in cells expressing hepatitis C virus core protein","volume":"50","author":"Tsutsumi","year":"2009","journal-title":"Hepatology"},{"key":"key20180108134016_b30-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1186\/1465-9921-11-104","article-title":"Expression and activation of the oxytocin receptor in airway smooth muscle cells: Regulation by TNFalpha and IL-13","volume":"11","author":"Amrani","year":"2010","journal-title":"Respir Res"},{"key":"key20180108134016_b31-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1038\/356526a0","article-title":"Structure and expression of a human oxytocin receptor","volume":"356","author":"Kimura","year":"1992","journal-title":"Nature"},{"key":"key20180108134016_b32-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1016\/S0006-3223(03)00465-7","article-title":"Social support and oxytocin interact to suppress cortisol and subjective responses to psychosocial stress","volume":"54","author":"Heinrichs","year":"2003","journal-title":"Biological Psychiatry"},{"key":"key20180108134016_b33-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.psyneuen.2010.07.003","article-title":"Oxytocin receptor gene polymorphism (rs2254298) interacts with familial risk for psychopathology to predict symptoms of depression and anxiety in adolescent girls","volume":"36","author":"Thompson","year":"2011","journal-title":"Psychoneuroendocrinology"},{"key":"key20180108134016_b34-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"e0127910","DOI":"10.1371\/journal.pone.0127910","article-title":"CRMP1 inhibits proliferation of medulloblastoma and is regulated by HMGA1","volume":"10","author":"Li","year":"2015","journal-title":"PLoS One"},{"key":"key20180108134016_b35-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1007\/s12035-014-9049-2","article-title":"CRMP1 interacted with Spy1 during the collapse of growth cones induced by Sema3A and acted on regeneration after sciatic nerve crush","volume":"53","author":"Yao","year":"2016","journal-title":"Mol Neurobiol"},{"key":"key20180108134016_b36-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.neuint.2009.03.005","article-title":"Upregulation of Dpysl2 and Spna2 gene expression in the rat brain after ischemic stroke","volume":"55","author":"Indraswari","year":"2009","journal-title":"Neurochem Int"},{"key":"key20180108134016_b37-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.ydbio.2012.07.032","article-title":"Dpysl2 (CRMP2) and Dpysl3 (CRMP4) phosphorylation by Cdk5 and DYRK2 is required for proper positioning of Rohon-Beard neurons and neural crest cells during neurulation in zebrafish","volume":"370","author":"Tanaka","year":"2012","journal-title":"Dev Biol"},{"key":"key20180108134016_b38-etm-0-0-4138","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.neuroscience.2012.04.052","article-title":"Involvement of the Akt\/GSK-3\u03b2\/CRMP-2 pathway in axonal injury after hypoxic-ischemic brain damage in neonatal rat","volume":"216","author":"Xiong","year":"2012","journal-title":"Neuroscience"},{"key":"key20180108134016_b39-etm-0-0-4138","first-page":"007","article-title":"CRMP-2 is involved in hypoxic preconditioning-induced neuroprotection against cerebral ischemic injuries of mice","volume":"11","author":"Zhang","year":"2009","journal-title":"Chin J Basic Clin Med"}],"container-title":["Experimental and Therapeutic Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/spandidos-publications.com\/10.3892\/etm.2017.4138\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,1,8]],"date-time":"2018-01-08T18:45:40Z","timestamp":1515437140000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spandidos-publications.com\/10.3892\/etm.2017.4138"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2,21]]},"references-count":39,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2017,2,21]]},"published-print":{"date-parts":[[2017,4]]}},"alternative-id":["10.3892\/etm.2017.4138"],"URL":"https:\/\/doi.org\/10.3892\/etm.2017.4138","relation":{},"ISSN":["1792-0981","1792-1015"],"issn-type":[{"value":"1792-0981","type":"print"},{"value":"1792-1015","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,2,21]]}}}